| 2021-02-02 | PalmeirasvBotafogo RJSerie A · Brazil | 1–1 | Serie A · Brazil |
| 2021-02-02 | Man UnitedvSouthamptonPremier League · England | 9–0 | Premier League · England |
| 2021-02-02 | Crawley TownvLeyton OrientLeague Two · England | 0–0 | League Two · England |
| 2021-02-02 | DunkerquevRodezLigue 2 · France | 0–0 | Ligue 2 · France |
| 2021-02-02 | RizesporvKasimpasaSüper Lig · Turkey | 1–1 | Süper Lig · Turkey |
| 2021-02-02 | Paris FCvNiortLigue 2 · France | 3–3 | Ligue 2 · France |
| 2021-02-02 | HataysporvFenerbahceSüper Lig · Turkey | 1–2 | Süper Lig · Turkey |
| 2021-02-02 | Boreham WoodvWeymouthNational League · England | 1–0 | National League · England |
| 2021-02-02 | CharltonvPortsmouthLeague One · England | 1–3 | League One · England |
| 2021-02-02 | Le HavrevNancyLigue 2 · France | 1–1 | Ligue 2 · France |
| 2021-02-02 | EastleighvWrexhamNational League · England | 1–1 | National League · England |
| 2021-02-02 | Gil VicentevPacos FerreiraPrimeira Liga · Portugal | 1–2 | Primeira Liga · Portugal |
| 2021-02-02 | AberdeenvLivingstonPremiership · Scotland | 0–2 | Premiership · Scotland |
| 2021-02-02 | AuxerrevToulouseLigue 2 · France | 3–1 | Ligue 2 · France |
| 2021-02-02 | Sheffield UnitedvWest BromPremier League · England | 2–1 | Premier League · England |
| 2021-02-02 | StockportvSuttonNational League · England | 0–2 | National League · England |
| 2021-02-02 | SwindonvWiganLeague One · England | 1–0 | League One · England |
| 2021-02-02 | PisavFrosinoneSerie B · Italy | 0–0 | Serie B · Italy |
| 2021-02-02 | WolvesvArsenalPremier League · England | 2–1 | Premier League · England |
| 2021-02-02 | NewcastlevCrystal PalacePremier League · England | 1–2 | Premier League · England |
| 2021-02-02 | ChateaurouxvChamblyLigue 2 · France | 4–0 | Ligue 2 · France |
| 2021-02-02 | BournemouthvSheffield WedsChampionship · England | 1–2 | Championship · England |
| 2021-02-02 | TorquayvAltrinchamNational League · England | 1–2 | National League · England |
| 2021-02-02 | Randers FCvHorsensSuperliga · Denmark | 3–0 | Superliga · Denmark |
| 2021-02-02 | CaenvValenciennesLigue 2 · France | 1–1 | Ligue 2 · France |
| 2021-02-02 | GalatasarayvBuyuksehyrSüper Lig · Turkey | 3–0 | Süper Lig · Turkey |
| 2021-02-02 | AccringtonvBristol RvsLeague One · England | 6–1 | League One · England |
| 2021-02-02 | AldershotvBarnetNational League · England | 2–1 | National League · England |
| 2021-02-02 | CoventryvNott'm ForestChampionship · England | 1–2 | Championship · England |
| 2021-02-02 | VejlevAarhusSuperliga · Denmark | 0–0 | Superliga · Denmark |
| 2021-02-02 | StevenagevExeterLeague Two · England | 0–1 | League Two · England |
| 2021-02-02 | Pau FCvAmiensLigue 2 · France | 2–0 | Ligue 2 · France |
| 2021-02-02 | MillwallvNorwichChampionship · England | 0–0 | Championship · England |
| 2021-02-02 | CarlislevForest GreenLeague Two · England | 1–2 | League Two · England |
| 2021-02-02 | Club LeonvAtl. San LuisLiga MX · Mexico | 3–1 | Liga MX · Mexico |
| 2021-02-02 | BlackpoolvNorthamptonLeague One · England | 2–0 | League One · England |
| 2021-02-02 | SochauxvAjaccioLigue 2 · France | 0–2 | Ligue 2 · France |
| 2021-02-02 | ClermontvTroyesLigue 2 · France | 2–1 | Ligue 2 · France |
| 2021-02-02 | GrenoblevGuingampLigue 2 · France | 2–1 | Ligue 2 · France |
| 2021-02-02 | St MirrenvHibernianPremiership · Scotland | 1–2 | Premiership · Scotland |
| 2021-02-01 | WatfordvQPRChampionship · England | 1–2 | Championship · England |
| 2021-02-01 | LeganesvLugoLa Liga 2 · Spain | 3–2 | La Liga 2 · Spain |
| 2021-02-01 | Sp LisbonvBenficaPrimeira Liga · Portugal | 1–0 | Primeira Liga · Portugal |
| 2021-02-01 | BetisvOsasunaLa Liga · Spain | 1–0 | La Liga · Spain |
| 2021-02-01 | MoreirensevSp BragaPrimeira Liga · Portugal | 0–4 | Primeira Liga · Portugal |
| 2021-02-01 | Sport RecifevFlamengo RJSerie A · Brazil | 0–3 | Serie A · Brazil |
| 2021-02-01 | Stal MielecvSlask WroclawEkstraklasa · Poland | 0–0 | Ekstraklasa · Poland |
| 2021-02-01 | Santos LagunavClub AmericaLiga MX · Mexico | 1–1 | Liga MX · Mexico |
| 2021-02-01 | Santa ClaravBelenensesPrimeira Liga · Portugal | 2–0 | Primeira Liga · Portugal |
| 2021-02-01 | RegginavSalernitanaSerie B · Italy | 0–0 | Serie B · Italy |