| 2022-01-15 | Oud-Heverlee LeuvenvMechelenPro League · Belgium | 5–0 | Pro League · Belgium |
| 2022-01-15 | Werder BremenvFortuna Dusseldorf2. Bundesliga · Germany | 3–0 | 2. Bundesliga · Germany |
| 2022-01-15 | AntalyasporvFenerbahceSüper Lig · Turkey | 1–1 | Süper Lig · Turkey |
| 2022-01-15 | StuttgartvRB LeipzigBundesliga · Germany | 0–2 | Bundesliga · Germany |
| 2022-01-15 | PeterborovCoventryChampionship · England | 1–4 | Championship · England |
| 2022-01-15 | NewcastlevWatfordPremier League · England | 1–1 | Premier League · England |
| 2022-01-15 | St PaulivErzgebirge Aue2. Bundesliga · Germany | 2–2 | 2. Bundesliga · Germany |
| 2022-01-15 | AyrvMortonChampionship · Scotland | 0–2 | Championship · Scotland |
| 2022-01-15 | TranmerevRochdaleLeague Two · England | 2–0 | League Two · England |
| 2022-01-15 | RodezvDijonLigue 2 · France | 0–2 | Ligue 2 · France |
| 2022-01-15 | StranraervStirlingLeague Two · Scotland | 3–3 | League Two · Scotland |
| 2022-01-15 | RegginavBresciaSerie B · Italy | 0–2 | Serie B · Italy |
| 2022-01-15 | Fleetwood TownvRotherhamLeague One · England | 1–0 | League One · England |
| 2022-01-15 | PisavFrosinoneSerie B · Italy | 1–3 | Serie B · Italy |
| 2022-01-15 | Inverness CvQueen of SthChampionship · Scotland | 2–2 | Championship · Scotland |
| 2022-01-15 | Club BruggevSt TruidenPro League · Belgium | 2–0 | Pro League · Belgium |
| 2022-01-15 | PeterheadvClydeLeague One · Scotland | 1–1 | League One · Scotland |
| 2022-01-15 |  South Koreav IcelandFriendly | 5–1 | Friendly |
| 2022-01-15 | PortsmouthvMilton Keynes DonsLeague One · England | 1–2 | League One · England |
| 2022-01-15 | Bristol RvsvHartlepoolLeague Two · England | 2–0 | League Two · England |
| 2022-01-15 | DoncastervWiganLeague One · England | 1–2 | League One · England |
| 2022-01-15 | SampdoriavTorinoSerie A · Italy | 1–2 | Serie A · Italy |
| 2022-01-15 | PAOKvOFI CreteSuper League · Greece | 3–0 | Super League · Greece |
| 2022-01-15 | ApollonvArisSuper League · Greece | 0–0 | Super League · Greece |
| 2022-01-15 | Port ValevSwindonLeague Two · England | 1–3 | League Two · England |
| 2022-01-15 | QPRvWest BromChampionship · England | 1–0 | Championship · England |
| 2022-01-15 | PrestonvBirminghamChampionship · England | 1–1 | Championship · England |
| 2022-01-15 | Aston VillavMan UnitedPremier League · England | 2–2 | Premier League · England |
| 2022-01-15 | LamiavIonikosSuper League · Greece | 2–1 | Super League · Greece |
| 2022-01-15 | NancyvBastiaLigue 2 · France | 2–1 | Ligue 2 · France |
| 2022-01-15 | AlloavQueens ParkLeague One · Scotland | 1–1 | League One · Scotland |
| 2022-01-15 | AccringtonvSunderlandLeague One · England | 1–1 | League One · England |
| 2022-01-15 | ExetervScunthorpeLeague Two · England | 2–0 | League Two · England |
| 2022-01-15 | BoavistavGil VicentePrimeira Liga · Portugal | 1–1 | Primeira Liga · Portugal |
| 2022-01-15 | Man CityvChelseaPremier League · England | 1–0 | Premier League · England |
| 2022-01-15 | BoltonvIpswichLeague One · England | 2–0 | League One · England |
| 2022-01-15 | AFC WimbledonvMorecambeLeague One · England | 0–0 | League One · England |
| 2022-01-15 | CarlislevCrawley TownLeague Two · England | 1–1 | League Two · England |
| 2022-01-15 | WolvesvSouthamptonPremier League · England | 3–1 | Premier League · England |
| 2022-01-15 | FeyenoordvVitesseEredivisie · Netherlands | 0–1 | Eredivisie · Netherlands |
| 2022-01-15 | BradfordvSalfordLeague Two · England | 2–1 | League Two · England |
| 2022-01-15 | Annan AthleticvForfarLeague Two · Scotland | 2–2 | League Two · Scotland |
| 2022-01-15 | Sp BragavMaritimoPrimeira Liga · Portugal | 0–1 | Primeira Liga · Portugal |
| 2022-01-15 | CardiffvBlackburnChampionship · England | 0–1 | Championship · England |
| 2022-01-15 | StenhousemuirvCowdenbeathLeague Two · Scotland | 0–2 | League Two · Scotland |
| 2022-01-15 | DunfermlinevHamiltonChampionship · Scotland | 1–0 | Championship · Scotland |
| 2022-01-15 | DerbyvSheffield UnitedChampionship · England | 2–0 | Championship · England |
| 2022-01-15 | JuventusvUdineseSerie A · Italy | 2–0 | Serie A · Italy |
| 2022-01-15 | Paris SGvBrestLigue 1 · France | 2–0 | Ligue 1 · France |
| 2022-01-15 | SochauxvCaenLigue 2 · France | 3–2 | Ligue 2 · France |