| 2016-01-30 | CordobavLeganesLaLiga 2 · Spain | 2–3 | LaLiga 2 · Spain |
| 2016-01-30 | AFC WimbledonvYeovilLeague Two · England | 2–3 | League Two · England |
| 2016-01-30 | CrotonevPerugiaSerie B · Italy | 1–2 | Serie B · Italy |
| 2016-01-30 | NijmegenvAZ AlkmaarEredivisie · Netherlands | 0–3 | Eredivisie · Netherlands |
| 2016-01-30 | RangersvFalkirkChampionship · Scotland | 1–0 | Championship · Scotland |
| 2016-01-30 | AccringtonvBristol RvsLeague Two · England | 1–0 | League Two · England |
| 2016-01-30 | TernanavModenaSerie B · Italy | 2–1 | Serie B · Italy |
| 2016-01-30 | Le HavrevLensLigue 2 · France | 2–0 | Ligue 2 · France |
| 2016-01-30 | VeracruzvClub TijuanaLiga MX · Mexico | 2–2 | Liga MX · Mexico |
| 2016-01-30 | HuddersfieldvCardiffChampionship · England | 2–3 | Championship · England |
| 2016-01-30 | AldershotvKidderminsterNational League · England | 1–0 | National League · England |
| 2016-01-30 | EastleighvWrexhamNational League · England | 1–1 | National League · England |
| 2016-01-30 | OviedovAlavesLaLiga 2 · Spain | 1–1 | LaLiga 2 · Spain |
| 2016-01-30 | KilmarnockvHamiltonPremiership · Scotland | 0–1 | Premiership · Scotland |
| 2016-01-30 | AtalantavSassuoloSerie A · Italy | 1–1 | Serie A · Italy |
| 2016-01-30 | VitessevExcelsiorEredivisie · Netherlands | 0–0 | Eredivisie · Netherlands |
| 2016-01-30 | GetafevAth BilbaoLaLiga · Spain | 0–1 | LaLiga · Spain |
| 2016-01-30 | HuescavAlbaceteLaLiga 2 · Spain | 3–1 | LaLiga 2 · Spain |
| 2016-01-30 | WesterlovWaregemPro League · Belgium | 1–2 | Pro League · Belgium |
| 2016-01-30 | EstorilvPortoPrimeira Liga · Portugal | 1–3 | Primeira Liga · Portugal |
| 2016-01-30 | PAOKvAtromitosSuper League Greece · Greece | 1–1 | Super League Greece · Greece |
| 2016-01-30 | SociedadvBetisLaLiga · Spain | 2–1 | LaLiga · Spain |
| 2016-01-30 | Angersv MonacoLigue 1 · France | 3–0 | Ligue 1 · France |
| 2016-01-30 | ZwollevGroningenEredivisie · Netherlands | 1–3 | Eredivisie · Netherlands |
| 2016-01-30 | PanthrakikosvPanioniosSuper League Greece · Greece | 0–1 | Super League Greece · Greece |
| 2016-01-30 | Leyton OrientvCambridgeLeague Two · England | 1–3 | League Two · England |
| 2016-01-30 | RochdalevBurtonLeague One · England | 2–1 | League One · England |
| 2016-01-30 | Ajaccio GFCOvMontpellierLigue 1 · France | 0–4 | Ligue 1 · France |
| 2016-01-30 | TroyesvNantesLigue 1 · France | 0–1 | Ligue 1 · France |
| 2016-01-30 | East StirlingvArbroathLeague Two · Scotland | 0–3 | League Two · Scotland |
| 2016-01-30 | LlagosteravLugoLaLiga 2 · Spain | 0–0 | LaLiga 2 · Spain |
| 2016-01-30 | LutonvNotts CountyLeague Two · England | 0–2 | League Two · England |
| 2016-01-30 | MorecambevNewport CountyLeague Two · England | 1–2 | League Two · England |
| 2016-01-30 | AugsburgvEin FrankfurtBundesliga · Germany | 0–0 | Bundesliga · Germany |
| 2016-01-30 | PescaravBariSerie B · Italy | 3–1 | Serie B · Italy |
| 2016-01-30 | WiganvPort ValeLeague One · England | 3–0 | League One · England |
| 2016-01-30 | Forest GreenvMacclesfieldNational League · England | 2–1 | National League · England |
| 2016-01-30 | EibarvMalagaLaLiga · Spain | 1–2 | LaLiga · Spain |
| 2016-01-30 | Virtus LancianovTrapaniSerie B · Italy | 0–3 | Serie B · Italy |
| 2016-01-30 | CharleroivMechelenPro League · Belgium | 3–2 | Pro League · Belgium |
| 2016-01-30 | Sp LisbonvAcademicaPrimeira Liga · Portugal | 3–2 | Primeira Liga · Portugal |
| 2016-01-30 | St MirrenvAlloaChampionship · Scotland | 3–1 | Championship · Scotland |
| 2016-01-30 | BresciavLivornoSerie B · Italy | 1–3 | Serie B · Italy |
| 2016-01-30 | Annan AthleticvElginLeague Two · Scotland | 4–2 | League Two · Scotland |
| 2016-01-30 | DundeevMotherwellPremiership · Scotland | 2–2 | Premiership · Scotland |
| 2016-01-30 | LincolnvGuiseleyNational League · England | 1–0 | National League · England |
| 2016-01-30 | LorientvReimsLigue 1 · France | 2–0 | Ligue 1 · France |
| 2016-01-30 | BradfordvFleetwood TownLeague One · England | 2–1 | League One · England |
| 2016-01-30 | LeverkusenvHannoverBundesliga · Germany | 3–0 | Bundesliga · Germany |
| 2016-01-30 | Santos LagunavQueretaroLiga MX · Mexico | 2–0 | Liga MX · Mexico |