| 2018-01-22 | EibarvMalagaLa Liga · Spain | 1–1 | La Liga · Spain |
| 2018-01-22 | JuventusvGenoaSerie A · Italy | 1–0 | Serie A · Italy |
| 2018-01-21 | GenkvAnderlechtPro League · Belgium | 0–1 | Pro League · Belgium |
| 2018-01-21 | Willem IIvGroningenEredivisie · Netherlands | 1–1 | Eredivisie · Netherlands |
| 2018-01-21 | BresciavAvellinoSerie B · Italy | 2–3 | Serie B · Italy |
| 2018-01-21 |  MonacovMetzLigue 1 · France | 3–1 | Ligue 1 · France |
| 2018-01-21 | OsasunavLeonesaLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2018-01-21 | AvesvPacos FerreiraPrimeira Liga · Portugal | 0–2 | Primeira Liga · Portugal |
| 2018-01-21 | IntervRomaSerie A · Italy | 1–1 | Serie A · Italy |
| 2018-01-21 | GentvLokerenPro League · Belgium | 3–0 | Pro League · Belgium |
| 2018-01-21 | Real MadridvLa CorunaLa Liga · Spain | 7–1 | La Liga · Spain |
| 2018-01-21 | LamiavAsteras TripolisSuper League · Greece | 1–0 | Super League · Greece |
| 2018-01-21 | TenerifevBarcelona BLa Liga 2 · Spain | 1–3 | La Liga 2 · Spain |
| 2018-01-21 | UNAM PumasvClub AmericaLiga MX · Mexico | 0–0 | Liga MX · Mexico |
| 2018-01-21 | UdinesevSpalSerie A · Italy | 1–1 | Serie A · Italy |
| 2018-01-21 | GianninavAtromitosSuper League · Greece | 2–2 | Super League · Greece |
| 2018-01-21 | GuimaraesvEstorilPrimeira Liga · Portugal | 3–1 | Primeira Liga · Portugal |
| 2018-01-21 | AtalantavNapoliSerie A · Italy | 0–1 | Serie A · Italy |
| 2018-01-21 | SouthamptonvTottenhamPremier League · England | 1–1 | Premier League · England |
| 2018-01-21 | BursasporvBuyuksehyrSüper Lig · Turkey | 0–3 | Süper Lig · Turkey |
| 2018-01-21 | NumanciavVallecanoLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2018-01-21 | AjaxvFeyenoordEredivisie · Netherlands | 2–0 | Eredivisie · Netherlands |
| 2018-01-21 | Schalke 04vHannoverBundesliga · Germany | 1–1 | Bundesliga · Germany |
| 2018-01-21 | VeronavCrotoneSerie A · Italy | 0–3 | Serie A · Italy |
| 2018-01-21 | LaziovChievoSerie A · Italy | 5–1 | Serie A · Italy |
| 2018-01-21 | AlcorconvCadizLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2018-01-21 | CagliarivMilanSerie A · Italy | 1–2 | Serie A · Italy |
| 2018-01-21 | KonyasporvTrabzonsporSüper Lig · Turkey | 2–2 | Süper Lig · Turkey |
| 2018-01-21 | Sparta RotterdamvExcelsiorEredivisie · Netherlands | 2–3 | Eredivisie · Netherlands |
| 2018-01-21 | PAOKvApollonSuper League · Greece | 3–0 | Super League · Greece |
| 2018-01-21 | FeirensevMoreirensePrimeira Liga · Portugal | 1–0 | Primeira Liga · Portugal |
| 2018-01-21 | GimnasticvReus DeportiuLa Liga 2 · Spain | 1–2 | La Liga 2 · Spain |
| 2018-01-21 | AlavesvLeganesLa Liga · Spain | 2–2 | La Liga · Spain |
| 2018-01-21 | LyonvParis SGLigue 1 · France | 2–1 | Ligue 1 · France |
| 2018-01-21 | SivassporvAkhisar BelediyesporSüper Lig · Turkey | 1–1 | Süper Lig · Turkey |
| 2018-01-21 | HeraclesvPSV EindhovenEredivisie · Netherlands | 1–2 | Eredivisie · Netherlands |
| 2018-01-21 | AntalyasporvBesiktasSüper Lig · Turkey | 1–2 | Süper Lig · Turkey |
| 2018-01-21 | PachucavLobos BUAPLiga MX · Mexico | 3–1 | Liga MX · Mexico |
| 2018-01-21 | SociedadvCeltaLa Liga · Spain | 1–2 | La Liga · Spain |
| 2018-01-21 | Bayern MunichvWerder BremenBundesliga · Germany | 4–2 | Bundesliga · Germany |
| 2018-01-21 | NicevSt EtienneLigue 1 · France | 1–0 | Ligue 1 · France |
| 2018-01-21 | BetisvBarcelonaLa Liga · Spain | 0–5 | La Liga · Spain |
| 2018-01-21 | AntwerpvClub BruggePro League · Belgium | 2–2 | Pro League · Belgium |
| 2018-01-21 | SampdoriavFiorentinaSerie A · Italy | 3–1 | Serie A · Italy |
| 2018-01-21 | SassuolovTorinoSerie A · Italy | 1–1 | Serie A · Italy |
| 2018-01-21 | NecaxavGuadalajara ChivasLiga MX · Mexico | 1–3 | Liga MX · Mexico |
| 2018-01-21 | MonterreyvClub TijuanaLiga MX · Mexico | 0–0 | Liga MX · Mexico |
| 2018-01-21 | Rio AvevBoavistaPrimeira Liga · Portugal | 2–0 | Primeira Liga · Portugal |
| 2018-01-21 | PanetolikosvPanioniosSuper League · Greece | 1–1 | Super League · Greece |
| 2018-01-21 | BolognavBeneventoSerie A · Italy | 3–0 | Serie A · Italy |