| 2016-01-24 | ElchevPonferradinaLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2016-01-24 | Guadalajara ChivasvTigres UANLLiga MX · Mexico | 2–2 | Liga MX · Mexico |
| 2016-01-24 | La CorunavValenciaLa Liga · Spain | 1–1 | La Liga · Spain |
| 2016-01-24 | Waasland-BeverenvClub BruggePro League · Belgium | 1–2 | Pro League · Belgium |
| 2016-01-24 | PortovMaritimoPrimeira Liga · Portugal | 1–0 | Primeira Liga · Portugal |
| 2016-01-24 | ZaragozavMirandesLa Liga 2 · Spain | 1–2 | La Liga 2 · Spain |
| 2016-01-24 | SampdoriavNapoliSerie A · Italy | 2–4 | Serie A · Italy |
| 2016-01-24 | PerugiavPescaraSerie B · Italy | 0–4 | Serie B · Italy |
| 2016-01-24 | HamiltonvHeartsPremiership · Scotland | 0–0 | Premiership · Scotland |
| 2016-01-24 | UtrechtvZwolleEredivisie · Netherlands | 1–0 | Eredivisie · Netherlands |
| 2016-01-24 | AnderlechtvCharleroiPro League · Belgium | 2–1 | Pro League · Belgium |
| 2016-01-24 | BetisvReal MadridLa Liga · Spain | 1–1 | La Liga · Spain |
| 2016-01-24 | Schalke 04vWerder BremenBundesliga · Germany | 1–3 | Bundesliga · Germany |
| 2016-01-24 | AlbacetevGimnasticLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2016-01-24 | ValladolidvCordobaLa Liga 2 · Spain | 2–0 | La Liga 2 · Spain |
| 2016-01-24 | LevadeiakosvPanathinaikosSuper League · Greece | 0–2 | Super League · Greece |
| 2016-01-24 | OsasunavLlagosteraLa Liga 2 · Spain | 3–0 | La Liga 2 · Spain |
| 2016-01-24 | BelenensesvGuimaraesPrimeira Liga · Portugal | 3–3 | Primeira Liga · Portugal |
| 2016-01-24 | GaziantepsporvBursasporSüper Lig · Turkey | 2–3 | Süper Lig · Turkey |
| 2016-01-24 | JuventusvRomaSerie A · Italy | 1–0 | Serie A · Italy |
| 2016-01-24 | StandardvGentPro League · Belgium | 0–3 | Pro League · Belgium |
| 2016-01-24 | EvertonvSwanseaPremier League · England | 1–2 | Premier League · England |
| 2016-01-24 | SassuolovBolognaSerie A · Italy | 0–2 | Serie A · Italy |
| 2016-01-24 | Den HaagvCambuurEredivisie · Netherlands | 2–1 | Eredivisie · Netherlands |
| 2016-01-24 | GenclerbirligivAntalyasporSüper Lig · Turkey | 1–0 | Süper Lig · Turkey |
| 2016-01-24 | Sp BragavRio AvePrimeira Liga · Portugal | 5–1 | Primeira Liga · Portugal |
| 2016-01-24 | ChiapasvVeracruzLiga MX · Mexico | 1–1 | Liga MX · Mexico |
| 2016-01-24 | AtromitosvGianninaSuper League · Greece | 0–2 | Super League · Greece |
| 2016-01-24 | LyonvMarseilleLigue 1 · France | 1–1 | Ligue 1 · France |
| 2016-01-24 | FenerbahcevRizesporSüper Lig · Turkey | 2–1 | Süper Lig · Turkey |
| 2016-01-24 | AEKvPAOKSuper League · Greece | 1–0 | Super League · Greece |
| 2016-01-24 | AZ AlkmaarvFeyenoordEredivisie · Netherlands | 4–2 | Eredivisie · Netherlands |
| 2016-01-24 | Club LeonvCruz AzulLiga MX · Mexico | 3–2 | Liga MX · Mexico |
| 2016-01-24 | MonarcasvTolucaLiga MX · Mexico | 1–1 | Liga MX · Mexico |
| 2016-01-24 | LaziovChievoSerie A · Italy | 4–1 | Serie A · Italy |
| 2016-01-24 | IntervCarpiSerie A · Italy | 1–1 | Serie A · Italy |
| 2016-01-24 | Ath MadridvSevillaLa Liga · Spain | 0–0 | La Liga · Spain |
| 2016-01-24 | TenerifevNumanciaLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2016-01-24 | UNAM PumasvPueblaLiga MX · Mexico | 0–1 | Liga MX · Mexico |
| 2016-01-24 | VeriavPanetolikosSuper League · Greece | 0–1 | Super League · Greece |
| 2016-01-24 |  MonacovToulouseLigue 1 · France | 4–0 | Ligue 1 · France |
| 2016-01-23 | MansfieldvLutonLeague Two · England | 0–2 | League Two · England |
| 2016-01-23 | EspanolvVillarrealLa Liga · Spain | 2–2 | La Liga · Spain |
| 2016-01-23 | HannovervDarmstadtBundesliga · Germany | 1–2 | Bundesliga · Germany |
| 2016-01-23 | WaregemvOud-Heverlee LeuvenPro League · Belgium | 2–2 | Pro League · Belgium |
| 2016-01-23 | MontrosevClydeLeague Two · Scotland | 2–1 | League Two · Scotland |
| 2016-01-23 | AlavesvHuescaLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2016-01-23 | SunderlandvBournemouthPremier League · England | 1–1 | Premier League · England |
| 2016-01-23 | Mouscron-PeruwelzvLokerenPro League · Belgium | 1–1 | Pro League · Belgium |
| 2016-01-23 | QPRvWolvesChampionship · England | 1–1 | Championship · England |