| 2021-02-20 | AmiensvSochauxLigue 2 · France | 0–1 | Ligue 2 · France |
| 2021-02-20 | PeterborovAFC WimbledonLeague One · England | 3–0 | League One · England |
| 2021-02-20 | M'gladbachvMainzBundesliga · Germany | 1–2 | Bundesliga · Germany |
| 2021-02-20 | HibernianvHamiltonPremiership · Scotland | 2–0 | Premiership · Scotland |
| 2021-02-20 | CoventryvBrentfordChampionship · England | 2–0 | Championship · England |
| 2021-02-20 | DunfermlinevAlloaChampionship · Scotland | 2–1 | Championship · Scotland |
| 2021-02-20 | Sao PaulovPalmeirasSerie A · Brazil | 1–1 | Serie A · Brazil |
| 2021-02-20 | Bristol CityvBarnsleyChampionship · England | 0–1 | Championship · England |
| 2021-02-20 | ValenciennesvTroyesLigue 2 · France | 2–2 | Ligue 2 · France |
| 2021-02-20 | BromleyvMaidenheadNational League · England | 2–2 | National League · England |
| 2021-02-20 | PortsmouthvBlackpoolLeague One · England | 0–1 | League One · England |
| 2021-02-20 | StevenagevWalsallLeague Two · England | 1–1 | League Two · England |
| 2021-02-20 | NecaxavMonterreyLiga MX · Mexico | 1–1 | Liga MX · Mexico |
| 2021-02-20 | Yeni MalatyasporvKonyasporSüper Lig · Turkey | 2–3 | Süper Lig · Turkey |
| 2021-02-20 | AlbacetevSp GijonLa Liga 2 · Spain | 0–1 | La Liga 2 · Spain |
| 2021-02-20 | CoritibavCearaSerie A · Brazil | 0–2 | Serie A · Brazil |
| 2021-02-20 | St PaulivDarmstadt2. Bundesliga · Germany | 3–2 | 2. Bundesliga · Germany |
| 2021-02-20 | AlanyasporvGalatasaraySüper Lig · Turkey | 0–1 | Süper Lig · Turkey |
| 2021-02-20 | AccringtonvShrewsburyLeague One · England | 1–1 | League One · England |
| 2021-02-20 | AberdeenvKilmarnockPremiership · Scotland | 1–0 | Premiership · Scotland |
| 2021-02-20 | MouscronvCercle BruggePro League · Belgium | 1–2 | Pro League · Belgium |
| 2021-02-20 | KasimpasavKaragumrukSüper Lig · Turkey | 3–2 | Süper Lig · Turkey |
| 2021-02-20 | HuddersfieldvSwanseaChampionship · England | 4–1 | Championship · England |
| 2021-02-20 | ChievovMonzaSerie B · Italy | 0–1 | Serie B · Italy |
| 2021-02-20 | For SittardvDen HaagEredivisie · Netherlands | 2–0 | Eredivisie · Netherlands |
| 2021-02-19 | BuyuksehyrvTrabzonsporSüper Lig · Turkey | 0–1 | Süper Lig · Turkey |
| 2021-02-19 | CagliarivTorinoSerie A · Italy | 0–1 | Serie A · Italy |
| 2021-02-19 | Willem IIvUtrechtEredivisie · Netherlands | 0–6 | Eredivisie · Netherlands |
| 2021-02-19 | Univ. CraiovavFC HermannstadtSuperliga · Romania | 1–0 | Superliga · Romania |
| 2021-02-19 | MechelenvGentPro League · Belgium | 1–1 | Pro League · Belgium |
| 2021-02-19 | Stal MielecvCracoviaEkstraklasa · Poland | 0–0 | Ekstraklasa · Poland |
| 2021-02-19 | PonferradinavMirandesLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2021-02-19 | WolvesvLeedsPremier League · England | 1–0 | Premier League · England |
| 2021-02-19 | FC VoluntarivFC ArgesSuperliga · Romania | 0–1 | Superliga · Romania |
| 2021-02-19 | BetisvGetafeLa Liga · Spain | 1–0 | La Liga · Spain |
| 2021-02-19 | BoavistavMoreirensePrimeira Liga · Portugal | 1–0 | Primeira Liga · Portugal |
| 2021-02-19 | FiorentinavSpeziaSerie A · Italy | 3–0 | Serie A · Italy |
| 2021-02-19 | BraunschweigvRegensburg2. Bundesliga · Germany | 2–0 | 2. Bundesliga · Germany |
| 2021-02-19 | BrestvLyonLigue 1 · France | 2–3 | Ligue 1 · France |
| 2021-02-19 | FrosinonevPescaraSerie B · Italy | 0–0 | Serie B · Italy |
| 2021-02-19 | BielefeldvWolfsburgBundesliga · Germany | 0–3 | Bundesliga · Germany |
| 2021-02-19 | Erzgebirge AuevBochum2. Bundesliga · Germany | 1–0 | 2. Bundesliga · Germany |
| 2021-02-19 | WatfordvDerbyChampionship · England | 2–1 | Championship · England |
| 2021-02-19 | Gimnasia L.P.vTalleres CordobaCopa De La Liga Profesional · Argentina | 3–0 | Copa De La Liga Profesional · Argentina |
| 2021-02-19 | AalborgvMidtjyllandSuperliga · Denmark | 0–2 | Superliga · Denmark |
| 2021-02-19 | WislavPogon SzczecinEkstraklasa · Poland | 2–1 | Ekstraklasa · Poland |
| 2021-02-19 | Atl. San LuisvSantos LagunaLiga MX · Mexico | 1–0 | Liga MX · Mexico |
| 2021-02-18 | ApollonvLamiaSuper League · Greece | 0–1 | Super League · Greece |
| 2021-02-18 | Tigres UANLvCruz AzulLiga MX · Mexico | 0–2 | Liga MX · Mexico |
| 2021-02-17 | St MirrenvHamiltonPremiership · Scotland | 1–1 | Premiership · Scotland |