| 2022-02-05 | BlackpoolvBristol CityChampionship · England | 3–1 | Championship · England |
| 2022-02-05 | OxfordvPortsmouthLeague One · England | 3–2 | League One · England |
| 2022-02-05 | NiortvLe HavreLigue 2 · France | 0–0 | Ligue 2 · France |
| 2022-02-05 | HarrogatevBradfordLeague Two · England | 2–0 | League Two · England |
| 2022-02-05 | FenerbahcevBuyuksehyrSüper Lig · Turkey | 0–1 | Süper Lig · Turkey |
| 2022-02-05 | ForfarvAlbion RvsLeague Two · Scotland | 2–0 | League Two · Scotland |
| 2022-02-05 | RomavGenoaSerie A · Italy | 0–0 | Serie A · Italy |
| 2022-02-05 | Kings LynnvWeymouthNational League · England | 3–0 | National League · England |
| 2022-02-05 | TwentevVitesseEredivisie · Netherlands | 3–0 | Eredivisie · Netherlands |
| 2022-02-05 | Lechia GdanskvSlask WroclawEkstraklasa · Poland | 2–0 | Ekstraklasa · Poland |
| 2022-02-05 | FalkirkvQueens ParkLeague One · Scotland | 1–1 | League One · Scotland |
| 2022-02-05 | BeneventovParmaSerie B · Italy | 0–0 | Serie B · Italy |
| 2022-02-05 | UTA AradvSepsi Sf. GheorgheSuperliga · Romania | 1–0 | Superliga · Romania |
| 2022-02-05 | Annan AthleticvStenhousemuirLeague Two · Scotland | 0–2 | League Two · Scotland |
| 2022-02-05 | TernanavRegginaSerie B · Italy | 2–0 | Serie B · Italy |
| 2022-02-05 | StuttgartvEin FrankfurtBundesliga · Germany | 2–3 | Bundesliga · Germany |
| 2022-02-05 | CosenzavBresciaSerie B · Italy | 0–0 | Serie B · Italy |
| 2022-02-05 | St EtiennevMontpellierLigue 1 · France | 3–1 | Ligue 1 · France |
| 2022-02-05 |  Cameroonv Burkina FasoAfrican Cup of Nations | 3–3 p | African Cup of Nations |
| 2022-02-05 | Bayern MunichvRB LeipzigBundesliga · Germany | 3–2 | Bundesliga · Germany |
| 2022-02-05 | Kelty HeartsvElginLeague Two · Scotland | 4–0 | League Two · Scotland |
| 2022-02-05 | DundeevRoss CountyPremiership · Scotland | 1–2 | Premiership · Scotland |
| 2022-02-05 | CharltonvAFC WimbledonLeague One · England | 3–2 | League One · England |
| 2022-02-05 | AscolivPerugiaSerie B · Italy | 0–1 | Serie B · Italy |
| 2022-02-05 | Milton Keynes DonsvLincolnLeague One · England | 2–1 | League One · England |
| 2022-02-05 | MaritimovEstorilPrimeira Liga · Portugal | 0–0 | Primeira Liga · Portugal |
| 2022-02-05 | East FifevClydeLeague One · Scotland | 0–0 | League One · Scotland |
| 2022-02-05 | IpswichvGillinghamLeague One · England | 1–0 | League One · England |
| 2022-02-05 | OsasunavSevillaLa Liga · Spain | 0–0 | La Liga · Spain |
| 2022-02-05 | Stal MielecvGornik Z.Ekstraklasa · Poland | 1–2 | Ekstraklasa · Poland |
| 2022-02-05 | PSV EindhovenvAZ AlkmaarEredivisie · Netherlands | 1–2 | Eredivisie · Netherlands |
| 2022-02-05 | ComovLecceSerie B · Italy | 1–1 | Serie B · Italy |
| 2022-02-05 |  MonacovLyonLigue 1 · France | 2–0 | Ligue 1 · France |
| 2022-02-05 | StandardvCercle BruggePro League · Belgium | 1–1 | Pro League · Belgium |
| 2022-02-04 | HeidenheimvHannover2. Bundesliga · Germany | 3–1 | 2. Bundesliga · Germany |
| 2022-02-04 | KayserisporvHataysporSüper Lig · Turkey | 4–3 | Süper Lig · Turkey |
| 2022-02-04 | ZaglebievLegiaEkstraklasa · Poland | 1–3 | Ekstraklasa · Poland |
| 2022-02-04 | GetafevLevanteLa Liga · Spain | 3–0 | La Liga · Spain |
| 2022-02-04 | AlmeriavIbizaLa Liga 2 · Spain | 2–0 | La Liga 2 · Spain |
| 2022-02-04 | Gaz Metan MediasvFC Rapid BucurestiSuperliga · Romania | 1–1 | Superliga · Romania |
| 2022-02-04 | ArbroathvKilmarnockChampionship · Scotland | 1–0 | Championship · Scotland |
| 2022-02-04 | Termalica B-B.vJagielloniaEkstraklasa · Poland | 2–1 | Ekstraklasa · Poland |
| 2022-02-04 | NurnbergvIngolstadt2. Bundesliga · Germany | 0–5 | 2. Bundesliga · Germany |
| 2022-02-04 | CharleroivSeraingPro League · Belgium | 2–0 | Pro League · Belgium |
| 2022-02-04 | HerthavBochumBundesliga · Germany | 1–1 | Bundesliga · Germany |
| 2022-02-04 | BurgosvAlcorconLa Liga 2 · Spain | 3–1 | La Liga 2 · Spain |
| 2022-02-04 | MarseillevAngersLigue 1 · France | 5–2 | Ligue 1 · France |
| 2022-02-04 | KonyasporvGiresunsporSüper Lig · Turkey | 1–0 | Süper Lig · Turkey |
| 2022-02-04 | BirminghamvSheffield UnitedChampionship · England | 1–2 | Championship · England |
| 2022-02-04 | MiovenivFC VoluntariSuperliga · Romania | 0–0 | Superliga · Romania |