| 2016-02-07 | AcademicavNacionalPrimeira Liga · Portugal | 2–2 | Primeira Liga · Portugal |
| 2016-02-07 | St. GallenvThunSuper League · Switzerland | 1–2 | Super League · Switzerland |
| 2016-02-07 | MonterreyvDorados de SinaloaLiga MX · Mexico | 3–0 | Liga MX · Mexico |
| 2016-02-07 | LokerenvOostendePro League · Belgium | 0–1 | Pro League · Belgium |
| 2016-02-07 | AlcorconvCordobaLa Liga 2 · Spain | 3–3 | La Liga 2 · Spain |
| 2016-02-06 | GalatasarayvKonyasporSüper Lig · Turkey | 0–0 | Süper Lig · Turkey |
| 2016-02-06 | Fortuna DusseldorfvHeidenheim2. Bundesliga · Germany | 0–1 | 2. Bundesliga · Germany |
| 2016-02-06 | VallecanovLas PalmasLa Liga · Spain | 2–0 | La Liga · Spain |
| 2016-02-06 | Queens ParkvElginLeague Two · Scotland | 0–0 | League Two · Scotland |
| 2016-02-06 | QueretarovVeracruzLiga MX · Mexico | 2–1 | Liga MX · Mexico |
| 2016-02-06 | StenhousemuirvDunfermlineLeague One · Scotland | 0–3 | League One · Scotland |
| 2016-02-06 | Young BoysvGrasshoppersSuper League · Switzerland | 1–1 | Super League · Switzerland |
| 2016-02-06 | KortrijkvWesterloPro League · Belgium | 1–1 | Pro League · Belgium |
| 2016-02-06 | ToulousevNantesLigue 1 · France | 0–0 | Ligue 1 · France |
| 2016-02-06 | WycombevLutonLeague Two · England | 0–1 | League Two · England |
| 2016-02-06 | PlataniasvAsteras TripolisSuper League · Greece | 2–0 | Super League · Greece |
| 2016-02-06 | Club AmericavSantos LagunaLiga MX · Mexico | 2–0 | Liga MX · Mexico |
| 2016-02-06 | Sp GijonvLa CorunaLa Liga · Spain | 1–1 | La Liga · Spain |
| 2016-02-06 | AscolivLatinaSerie B · Italy | 0–0 | Serie B · Italy |
| 2016-02-06 | CharltonvBristol CityChampionship · England | 0–1 | Championship · England |
| 2016-02-06 | BurnleyvHullChampionship · England | 1–0 | Championship · England |
| 2016-02-06 | LorientvMontpellierLigue 1 · France | 1–1 | Ligue 1 · France |
| 2016-02-06 | Ath MadridvEibarLa Liga · Spain | 3–1 | La Liga · Spain |
| 2016-02-06 | AyrvPeterheadLeague One · Scotland | 1–2 | League One · Scotland |
| 2016-02-06 | Munich 1860vNurnberg2. Bundesliga · Germany | 0–1 | 2. Bundesliga · Germany |
| 2016-02-06 | Pro VercellivBresciaSerie B · Italy | 2–1 | Serie B · Italy |
| 2016-02-06 | ChesterfieldvPeterboroLeague One · England | 0–1 | League One · England |
| 2016-02-06 | CarlislevAccringtonLeague Two · England | 2–0 | League Two · England |
| 2016-02-06 | SalernitanavPescaraSerie B · Italy | 2–2 | Serie B · Italy |
| 2016-02-06 | CrewevRochdaleLeague One · England | 2–0 | League One · England |
| 2016-02-06 | AldosivivOlimpo Bahia BlancaLiga Profesional · Argentina | 3–0 | Liga Profesional · Argentina |
| 2016-02-06 | BarrowvCheltenhamNational League · England | 1–2 | National League · England |
| 2016-02-06 | WaregemvCharleroiPro League · Belgium | 2–3 | Pro League · Belgium |
| 2016-02-06 | Ein FrankfurtvStuttgartBundesliga · Germany | 2–4 | Bundesliga · Germany |
| 2016-02-06 | Ath BilbaovVillarrealLa Liga · Spain | 0–0 | La Liga · Spain |
| 2016-02-06 | TranmerevSouthportNational League · England | 1–0 | National League · England |
| 2016-02-06 | StevenagevCrawley TownLeague Two · England | 0–1 | League Two · England |
| 2016-02-06 | IngolstadtvAugsburgBundesliga · Germany | 2–1 | Bundesliga · Germany |
| 2016-02-06 | PortsmouthvLeyton OrientLeague Two · England | 0–1 | League Two · England |
| 2016-02-06 | NorthamptonvYorkLeague Two · England | 2–0 | League Two · England |
| 2016-02-06 | NewcastlevWest BromPremier League · England | 1–0 | Premier League · England |
| 2016-02-06 | TenerifevHuescaLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2016-02-06 | BolognavFiorentinaSerie A · Italy | 1–1 | Serie A · Italy |
| 2016-02-06 | Welling UnitedvAltrinchamNational League · England | 1–1 | National League · England |
| 2016-02-06 | Mouscron-PeruwelzvGenkPro League · Belgium | 0–1 | Pro League · Belgium |
| 2016-02-06 | TondelavGuimaraesPrimeira Liga · Portugal | 1–1 | Primeira Liga · Portugal |
| 2016-02-06 | AltachvSturm GrazBundesliga · Austria | 2–2 | Bundesliga · Austria |
| 2016-02-06 |  MonacovNiceLigue 1 · France | 1–0 | Ligue 1 · France |
| 2016-02-06 | Waasland-BeverenvOud-Heverlee LeuvenPro League · Belgium | 2–2 | Pro League · Belgium |
| 2016-02-06 | MontrosevEast FifeLeague Two · Scotland | 2–2 | League Two · Scotland |