| 2021-03-03 | CagliarivBolognaSerie A · Italy | 1–0 | Serie A · Italy |
| 2021-03-03 | MetzvAngersLigue 1 · France | 0–1 | Ligue 1 · France |
| 2021-03-03 | St EtiennevLensLigue 1 · France | 2–3 | Ligue 1 · France |
| 2021-03-03 | Club LeonvPueblaLiga MX · Mexico | 1–2 | Liga MX · Mexico |
| 2021-03-03 | St. GallenvServetteSuper League · Switzerland | 0–1 | Super League · Switzerland |
| 2021-03-03 | LivingstonvRangersPremiership · Scotland | 0–1 | Premiership · Scotland |
| 2021-03-03 | BrestvDijonLigue 1 · France | 3–1 | Ligue 1 · France |
| 2021-03-02 | WiganvCharltonLeague One · England | 0–1 | League One · England |
| 2021-03-02 | NiortvSochauxLigue 2 · France | 1–3 | Ligue 2 · France |
| 2021-03-02 | ChievovPordenoneSerie B · Italy | 3–0 | Serie B · Italy |
| 2021-03-02 | HuddersfieldvBirminghamChampionship · England | 1–1 | Championship · England |
| 2021-03-02 | AjacciovRodezLigue 2 · France | 1–0 | Ligue 2 · France |
| 2021-03-02 | BlackpoolvCreweLeague One · England | 1–1 | League One · England |
| 2021-03-02 | HalifaxvHartlepoolNational League · England | 1–1 | National League · England |
| 2021-03-02 | BresciavCosenzaSerie B · Italy | 2–0 | Serie B · Italy |
| 2021-03-02 | ChesterfieldvEastleighNational League · England | 1–0 | National League · England |
| 2021-03-02 | GrimsbyvLeyton OrientLeague Two · England | 0–1 | League Two · England |
| 2021-03-02 | CoventryvMiddlesbroughChampionship · England | 1–2 | Championship · England |
| 2021-03-02 | ExetervWalsallLeague Two · England | 0–0 | League Two · England |
| 2021-03-02 | AccringtonvIpswichLeague One · England | 1–2 | League One · England |
| 2021-03-02 | JuventusvSpeziaSerie A · Italy | 3–0 | Serie A · Italy |
| 2021-03-02 | CheltenhamvSouthendLeague Two · England | 1–0 | League Two · England |
| 2021-03-02 | LeccevVirtus EntellaSerie B · Italy | 0–0 | Serie B · Italy |
| 2021-03-02 | ValenciennesvToulouseLigue 2 · France | 1–0 | Ligue 2 · France |
| 2021-03-02 | FrosinonevMonzaSerie B · Italy | 2–2 | Serie B · Italy |
| 2021-03-02 | ChamblyvTroyesLigue 2 · France | 0–3 | Ligue 2 · France |
| 2021-03-02 | DoncastervPortsmouthLeague One · England | 2–1 | League One · England |
| 2021-03-02 | SunderlandvSwindonLeague One · England | 1–0 | League One · England |
| 2021-03-02 | OxfordvPeterboroLeague One · England | 0–0 | League One · England |
| 2021-03-02 | SalernitanavSpalSerie B · Italy | 0–0 | Serie B · Italy |
| 2021-03-02 | WealdstonevBoreham WoodNational League · England | 1–0 | National League · England |
| 2021-03-02 | Yeni MalatyasporvBesiktasSüper Lig · Turkey | 0–1 | Süper Lig · Turkey |
| 2021-03-02 | StevenagevForest GreenLeague Two · England | 3–0 | League Two · England |
| 2021-03-02 | ShrewsburyvAFC WimbledonLeague One · England | 1–1 | League One · England |
| 2021-03-02 | Pau FCvChateaurouxLigue 2 · France | 1–0 | Ligue 2 · France |
| 2021-03-02 | MorecambevCrawley TownLeague Two · England | 3–1 | League Two · England |
| 2021-03-02 | Le HavrevGrenobleLigue 2 · France | 0–2 | Ligue 2 · France |
| 2021-03-02 | CittadellavPescaraSerie B · Italy | 0–1 | Serie B · Italy |
| 2021-03-02 | ColchestervCarlisleLeague Two · England | 2–1 | League Two · England |
| 2021-03-02 | AtlasvAtl. San LuisLiga MX · Mexico | 3–1 | Liga MX · Mexico |
| 2021-03-02 | BarnetvYeovilNational League · England | 1–4 | National League · England |
| 2021-03-02 | HullvRochdaleLeague One · England | 2–0 | League One · England |
| 2021-03-02 | AscolivPisaSerie B · Italy | 0–2 | Serie B · Italy |
| 2021-03-02 | GaziantepvGenclerbirligiSüper Lig · Turkey | 2–1 | Süper Lig · Turkey |
| 2021-03-02 | Paris FCvDunkerqueLigue 2 · France | 1–0 | Ligue 2 · France |
| 2021-03-02 | BradfordvMansfieldLeague Two · England | 1–0 | League Two · England |
| 2021-03-02 | GillinghamvMilton Keynes DonsLeague One · England | 3–2 | League One · England |
| 2021-03-02 | MillwallvPrestonChampionship · England | 2–1 | Championship · England |
| 2021-03-02 | VicenzavCremoneseSerie B · Italy | 3–1 | Serie B · Italy |
| 2021-03-02 | NancyvCaenLigue 2 · France | 1–0 | Ligue 2 · France |