| 2016-02-20 | Airdrie UtdvStranraerLeague One · Scotland | 1–1 | League One · Scotland |
| 2016-02-20 | QueretarovTigres UANLLiga MX · Mexico | 2–2 | Liga MX · Mexico |
| 2016-02-20 | Korona KielcevLechia GdanskEkstraklasa · Poland | 4–2 | Ekstraklasa · Poland |
| 2016-02-20 | LorientvGuingampLigue 1 · France | 4–3 | Ligue 1 · France |
| 2016-02-20 | ClydevBerwickLeague Two · Scotland | 2–1 | League Two · Scotland |
| 2016-02-20 | Sheffield UnitedvPort ValeLeague One · England | 1–0 | League One · England |
| 2016-02-20 | CowdenbeathvPeterheadLeague One · Scotland | 2–3 | League One · Scotland |
| 2016-02-20 | ModenavBresciaSerie B · Italy | 1–0 | Serie B · Italy |
| 2016-02-20 | BuryvColchesterLeague One · England | 5–2 | League One · England |
| 2016-02-20 | CagliarivPescaraSerie B · Italy | 2–1 | Serie B · Italy |
| 2016-02-20 | OxfordvAccringtonLeague Two · England | 1–2 | League Two · England |
| 2016-02-20 | Pacos FerreiravBenficaPrimeira Liga · Portugal | 1–3 | Primeira Liga · Portugal |
| 2016-02-20 | BarnetvAFC WimbledonLeague Two · England | 1–2 | League Two · England |
| 2016-02-20 | AngersvMontpellierLigue 1 · France | 2–3 | Ligue 1 · France |
| 2016-02-20 | AdmiravRiedBundesliga · Austria | 0–0 | Bundesliga · Austria |
| 2016-02-19 | Ein FrankfurtvHamburgBundesliga · Germany | 0–0 | Bundesliga · Germany |
| 2016-02-19 | Piast GliwicevPogon SzczecinEkstraklasa · Poland | 0–0 | Ekstraklasa · Poland |
| 2016-02-19 | River PlatevGodoy CruzLiga Profesional · Argentina | 1–2 | Liga Profesional · Argentina |
| 2016-02-19 | NancyvParis FCLigue 2 · France | 3–2 | Ligue 2 · France |
| 2016-02-19 | AuxerrevAjaccioLigue 2 · France | 0–0 | Ligue 2 · France |
| 2016-02-19 | BordeauxvNiceLigue 1 · France | 0–0 | Ligue 1 · France |
| 2016-02-19 | St PaulivFrankfurt FSV2. Bundesliga · Germany | 1–3 | 2. Bundesliga · Germany |
| 2016-02-19 | BrestvRed StarLigue 2 · France | 0–1 | Ligue 2 · France |
| 2016-02-19 | Den HaagvZwolleEredivisie · Netherlands | 0–2 | Eredivisie · Netherlands |
| 2016-02-19 | Atl. TucumanvUnion de Santa FeLiga Profesional · Argentina | 2–0 | Liga Profesional · Argentina |
| 2016-02-19 | LevantevGetafeLa Liga · Spain | 3–0 | La Liga · Spain |
| 2016-02-19 | LavalvDijonLigue 2 · France | 2–2 | Ligue 2 · France |
| 2016-02-19 | FC BotosanivAstraSuperliga · Romania | 0–1 | Superliga · Romania |
| 2016-02-19 | KonyasporvSivassporSüper Lig · Turkey | 2–1 | Süper Lig · Turkey |
| 2016-02-19 | BarivLatinaSerie B · Italy | 0–0 | Serie B · Italy |
| 2016-02-19 | RB LeipzigvUnion Berlin2. Bundesliga · Germany | 3–0 | 2. Bundesliga · Germany |
| 2016-02-19 | Evian Thonon GaillardvBourg PeronnasLigue 2 · France | 1–1 | Ligue 2 · France |
| 2016-02-19 | SochauxvLensLigue 2 · France | 0–0 | Ligue 2 · France |
| 2016-02-19 | Uniao MadeiravEstorilPrimeira Liga · Portugal | 1–1 | Primeira Liga · Portugal |
| 2016-02-19 | ToursvValenciennesLigue 2 · France | 1–0 | Ligue 2 · France |
| 2016-02-19 | Greuther FurthvDuisburg2. Bundesliga · Germany | 1–1 | 2. Bundesliga · Germany |
| 2016-02-19 | JagielloniavSlask WroclawEkstraklasa · Poland | 2–1 | Ekstraklasa · Poland |
| 2016-02-19 | ClermontvNiortLigue 2 · France | 2–1 | Ligue 2 · France |
| 2016-02-19 | BolognavJuventusSerie A · Italy | 0–0 | Serie A · Italy |
| 2016-02-19 | Club BruggevWesterloPro League · Belgium | 6–0 | Pro League · Belgium |
| 2016-02-18 | Colon Santa FEvBelgranoLiga Profesional · Argentina | 3–0 | Liga Profesional · Argentina |
| 2016-02-18 | San Martin S.J.vBoca JuniorsLiga Profesional · Argentina | 0–1 | Liga Profesional · Argentina |
| 2016-02-18 | Sarmiento JuninvGimnasia L.P.Liga Profesional · Argentina | 1–3 | Liga Profesional · Argentina |
| 2016-02-18 | TemperleyvLanusLiga Profesional · Argentina | 0–1 | Liga Profesional · Argentina |
| 2016-02-18 | Estudiantes L.P.vTigreLiga Profesional · Argentina | 1–1 | Liga Profesional · Argentina |
| 2016-02-17 | BesiktasvMersin Idman YurduSüper Lig · Turkey | 1–0 | Süper Lig · Turkey |
| 2016-02-17 | Argentinos JrsvVelez SarsfieldLiga Profesional · Argentina | 0–3 | Liga Profesional · Argentina |
| 2016-02-17 | Defensa y JusticiavAtl. RafaelaLiga Profesional · Argentina | 4–1 | Liga Profesional · Argentina |
| 2016-02-17 | IndependientevRosario CentralLiga Profesional · Argentina | 0–2 | Liga Profesional · Argentina |
| 2016-02-17 | PatronatovArsenal SarandiLiga Profesional · Argentina | 0–0 | Liga Profesional · Argentina |