| 2021-03-09 | WokingvBoreham WoodNational League · England | 0–0 | National League · England |
| 2021-03-09 | Forest GreenvMorecambeLeague Two · England | 2–2 | League Two · England |
| 2021-03-09 | River PlatevArgentinos JrsCopa De La Liga Profesional · Argentina | 0–1 | Copa De La Liga Profesional · Argentina |
| 2021-03-09 | SuttonvYeovilNational League · England | 2–1 | National League · England |
| 2021-03-09 | Dag and RedvMaidenheadNational League · England | 2–1 | National League · England |
| 2021-03-09 | Crawley TownvSalfordLeague Two · England | 1–0 | League Two · England |
| 2021-03-09 | Bristol RvsvAccringtonLeague One · England | 4–1 | League One · England |
| 2021-03-09 | SwindonvOxfordLeague One · England | 1–2 | League One · England |
| 2021-03-09 | Fleetwood TownvGillinghamLeague One · England | 1–0 | League One · England |
| 2021-03-09 | Sp BragavGuimaraesPrimeira Liga · Portugal | 3–0 | Primeira Liga · Portugal |
| 2021-03-09 | WealdstonevKings LynnNational League · England | 3–1 | National League · England |
| 2021-03-08 | AntalyasporvKasimpasaSüper Lig · Turkey | 1–1 | Süper Lig · Turkey |
| 2021-03-08 | West HamvLeedsPremier League · England | 2–0 | Premier League · England |
| 2021-03-08 | FC ArgesvPoli IasiSuperliga · Romania | 2–1 | Superliga · Romania |
| 2021-03-08 | ChievovVicenzaSerie B · Italy | 1–2 | Serie B · Italy |
| 2021-03-08 | Santos LagunavNecaxaLiga MX · Mexico | 3–1 | Liga MX · Mexico |
| 2021-03-08 | AEKvApollonSuper League · Greece | 2–0 | Super League · Greece |
| 2021-03-08 | Rubin KazanvZenitPremier League · Russia | 2–1 | Premier League · Russia |
| 2021-03-08 | IntervAtalantaSerie A · Italy | 1–0 | Serie A · Italy |
| 2021-03-08 | HamburgvHolstein Kiel2. Bundesliga · Germany | 1–1 | 2. Bundesliga · Germany |
| 2021-03-08 | Warta PoznanvWisla PlockEkstraklasa · Poland | 2–0 | Ekstraklasa · Poland |
| 2021-03-08 | BelenensesvBenficaPrimeira Liga · Portugal | 0–3 | Primeira Liga · Portugal |
| 2021-03-08 | GentvOostendePro League · Belgium | 1–0 | Pro League · Belgium |
| 2021-03-08 | BetisvAlavesLa Liga · Spain | 3–2 | La Liga · Spain |
| 2021-03-08 | TrabzonsporvAlanyasporSüper Lig · Turkey | 1–3 | Süper Lig · Turkey |
| 2021-03-08 | ChelseavEvertonPremier League · England | 2–0 | Premier League · England |
| 2021-03-08 | Racing ClubvRosario CentralCopa De La Liga Profesional · Argentina | 1–0 | Copa De La Liga Profesional · Argentina |
| 2021-03-08 | Arsenal TulavLokomotiv MoscowPremier League · Russia | 0–3 | Premier League · Russia |
| 2021-03-08 | Velez SarsfieldvBoca JuniorsCopa De La Liga Profesional · Argentina | 1–7 | Copa De La Liga Profesional · Argentina |
| 2021-03-08 | AlcorconvMirandesLa Liga 2 · Spain | 4–0 | La Liga 2 · Spain |
| 2021-03-08 | GoztepvErzurum BBSüper Lig · Turkey | 3–1 | Süper Lig · Turkey |
| 2021-03-08 | FC VoluntarivDin. BucurestiSuperliga · Romania | 1–1 | Superliga · Romania |
| 2021-03-08 | UNAM PumasvCruz AzulLiga MX · Mexico | 0–1 | Liga MX · Mexico |
| 2021-03-08 | KonyasporvFenerbahceSüper Lig · Turkey | 0–3 | Süper Lig · Turkey |
| 2021-03-08 | AalborgvSonderjyskeSuperliga · Denmark | 1–0 | Superliga · Denmark |
| 2021-03-08 | LugovFuenlabradaLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2021-03-07 | SalzburgvSt. PoltenBundesliga · Austria | 4–1 | Bundesliga · Austria |
| 2021-03-07 | For SittardvPSV EindhovenEredivisie · Netherlands | 1–3 | Eredivisie · Netherlands |
| 2021-03-07 | VeronavMilanSerie A · Italy | 0–2 | Serie A · Italy |
| 2021-03-07 | PonferradinavSp GijonLa Liga 2 · Spain | 2–2 | La Liga 2 · Spain |
| 2021-03-07 | Rio AvevFarensePrimeira Liga · Portugal | 2–0 | Primeira Liga · Portugal |
| 2021-03-07 | BielefeldvUnion BerlinBundesliga · Germany | 0–0 | Bundesliga · Germany |
| 2021-03-07 | PatronatovUnion de Santa FeCopa De La Liga Profesional · Argentina | 0–1 | Copa De La Liga Profesional · Argentina |
| 2021-03-07 | BraunschweigvSandhausen2. Bundesliga · Germany | 1–0 | 2. Bundesliga · Germany |
| 2021-03-07 | FiorentinavParmaSerie A · Italy | 3–3 | Serie A · Italy |
| 2021-03-07 | NapolivBolognaSerie A · Italy | 3–1 | Serie A · Italy |
| 2021-03-07 | FCSBvGaz Metan MediasSuperliga · Romania | 1–0 | Superliga · Romania |
| 2021-03-07 | EmpolivCittadellaSerie B · Italy | 1–1 | Serie B · Italy |
| 2021-03-07 | OlympiakosvLamiaSuper League · Greece | 3–0 | Super League · Greece |
| 2021-03-07 | Randers FCvLyngbySuperliga · Denmark | 1–2 | Superliga · Denmark |