| 2021-03-13 | Yokohama FCvCerezo OsakaJ1 League · Japan | 1–4 | J1 League · Japan |
| 2021-03-13 | LegiavWarta PoznanEkstraklasa · Poland | 3–2 | Ekstraklasa · Poland |
| 2021-03-13 | Sparta RotterdamvWaalwijkEredivisie · Netherlands | 2–0 | Eredivisie · Netherlands |
| 2021-03-13 | SochauxvChateaurouxLigue 2 · France | 0–0 | Ligue 2 · France |
| 2021-03-13 | MorecambevNewport CountyLeague Two · England | 1–3 | League Two · England |
| 2021-03-13 | CrewevBurtonLeague One · England | 0–3 | League One · England |
| 2021-03-13 | QPRvHuddersfieldChampionship · England | 0–1 | Championship · England |
| 2021-03-13 | ExetervCheltenhamLeague Two · England | 0–1 | League Two · England |
| 2021-03-13 | DundeevArbroathChampionship · Scotland | 2–0 | Championship · Scotland |
| 2021-03-13 | TroyesvNancyLigue 2 · France | 1–5 | Ligue 2 · France |
| 2021-03-13 | TondelavSp LisbonPrimeira Liga · Portugal | 0–1 | Primeira Liga · Portugal |
| 2021-03-13 | AngersvSt EtienneLigue 1 · France | 0–1 | Ligue 1 · France |
| 2021-03-13 | Real MadridvElcheLa Liga · Spain | 2–1 | La Liga · Spain |
| 2021-03-13 | Santa ClaravPortimonensePrimeira Liga · Portugal | 2–0 | Primeira Liga · Portugal |
| 2021-03-13 | AZ AlkmaarvTwenteEredivisie · Netherlands | 4–1 | Eredivisie · Netherlands |
| 2021-03-13 | FrosinonevBresciaSerie B · Italy | 0–1 | Serie B · Italy |
| 2021-03-13 | Crawley TownvMansfieldLeague Two · England | 1–0 | League Two · England |
| 2021-03-13 | MainzvFreiburgBundesliga · Germany | 1–0 | Bundesliga · Germany |
| 2021-03-13 | SwindonvGillinghamLeague One · England | 1–3 | League One · England |
| 2021-03-13 | Port ValevBoltonLeague Two · England | 0–1 | League Two · England |
| 2021-03-13 | WycombevPrestonChampionship · England | 1–0 | Championship · England |
| 2021-03-13 | BlackpoolvFleetwood TownLeague One · England | 0–0 | League One · England |
| 2021-03-13 | HullvOxfordLeague One · England | 2–0 | League One · England |
| 2021-03-13 | UralvR. VolgogradPremier League · Russia | 1–0 | Premier League · Russia |
| 2021-03-13 | CastellonvSabadellLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2021-03-13 | SassuolovVeronaSerie A · Italy | 3–2 | Serie A · Italy |
| 2021-03-13 | Argentinos JrsvGodoy CruzCopa De La Liga Profesional · Argentina | 2–0 | Copa De La Liga Profesional · Argentina |
| 2021-03-13 | FC HermannstadtvViitorul ConstantaSuperliga · Romania | 0–0 | Superliga · Romania |
| 2021-03-13 | MarseillevBrestLigue 1 · France | 3–1 | Ligue 1 · France |
| 2021-03-13 | WrexhamvWeymouthNational League · England | 2–0 | National League · England |
| 2021-03-13 | DortmundvHerthaBundesliga · Germany | 2–0 | Bundesliga · Germany |
| 2021-03-13 | GironavLugoLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2021-03-13 | HuracanvLanusCopa De La Liga Profesional · Argentina | 0–0 | Copa De La Liga Profesional · Argentina |
| 2021-03-13 | Vissel KobevNagoya GrampusJ1 League · Japan | 0–1 | J1 League · Japan |
| 2021-03-13 | Academica ClincenivFC VoluntariSuperliga · Romania | 0–1 | Superliga · Romania |
| 2021-03-13 | HalifaxvSolihullNational League · England | 1–0 | National League · England |
| 2021-03-13 | LeedsvChelseaPremier League · England | 0–0 | Premier League · England |
| 2021-03-13 | LivingstonvHamiltonPremiership · Scotland | 2–1 | Premiership · Scotland |
| 2021-03-13 | Forest GreenvHarrogateLeague Two · England | 2–1 | League Two · England |
| 2021-03-13 | DerbyvMillwallChampionship · England | 0–1 | Championship · England |
| 2021-03-13 |  Kenyav South SudanFriendly | 1–0 | Friendly |
| 2021-03-13 | AscolivVeneziaSerie B · Italy | 1–1 | Serie B · Italy |
| 2021-03-13 | VicenzavEmpoliSerie B · Italy | 0–2 | Serie B · Italy |
| 2021-03-13 | SalzburgvAdmiraBundesliga · Austria | 3–1 | Bundesliga · Austria |
| 2021-03-13 | RodezvValenciennesLigue 2 · France | 3–0 | Ligue 2 · France |
| 2021-03-13 | PordenonevPescaraSerie B · Italy | 0–0 | Serie B · Italy |
| 2021-03-13 | Kawasaki FrontalevKashiwa ReysolJ1 League · Japan | 1–0 | J1 League · Japan |
| 2021-03-13 | FulhamvMan CityPremier League · England | 0–3 | Premier League · England |
| 2021-03-13 | BeneventovFiorentinaSerie A · Italy | 1–4 | Serie A · Italy |
| 2021-03-13 | HeartsvAyrChampionship · Scotland | 2–0 | Championship · Scotland |