| 2016-02-28 | MaritimovAcademicaPrimeira Liga · Portugal | 1–0 | Primeira Liga · Portugal |
| 2016-02-28 | Gamba OsakavKashima AntlersJ1 League · Japan | 0–1 | J1 League · Japan |
| 2016-02-28 | AnderlechtvStandardPro League · Belgium | 3–3 | Pro League · Belgium |
| 2016-02-28 | Tigres UANLvClub AmericaLiga MX · Mexico | 4–1 | Liga MX · Mexico |
| 2016-02-28 | Racing ClubvBoca JuniorsLiga Profesional · Argentina | 1–0 | Liga Profesional · Argentina |
| 2016-02-28 | Dorados de SinaloavAtlasLiga MX · Mexico | 2–1 | Liga MX · Mexico |
| 2016-02-28 | HeidenheimvBielefeld2. Bundesliga · Germany | 3–2 | 2. Bundesliga · Germany |
| 2016-02-28 | AugsburgvM'gladbachBundesliga · Germany | 2–2 | Bundesliga · Germany |
| 2016-02-28 | TottenhamvSwanseaPremier League · England | 2–1 | Premier League · England |
| 2016-02-28 | ChestervTranmereNational League · England | 0–1 | National League · England |
| 2016-02-28 | BelenensesvPortoPrimeira Liga · Portugal | 1–2 | Primeira Liga · Portugal |
| 2016-02-28 | OlympiakosvVeriaSuper League · Greece | 3–0 | Super League · Greece |
| 2016-02-28 | BrondbyvHobroSuperliga · Denmark | 1–0 | Superliga · Denmark |
| 2016-02-28 | MirandesvTenerifeLa Liga 2 · Spain | 1–2 | La Liga 2 · Spain |
| 2016-02-28 | AjaxvAZ AlkmaarEredivisie · Netherlands | 4–1 | Eredivisie · Netherlands |
| 2016-02-28 | ChievovGenoaSerie A · Italy | 1–0 | Serie A · Italy |
| 2016-02-28 | TolucavPachucaLiga MX · Mexico | 0–1 | Liga MX · Mexico |
| 2016-02-28 | UdinesevVeronaSerie A · Italy | 2–0 | Serie A · Italy |
| 2016-02-28 | Nantesv MonacoLigue 1 · France | 0–0 | Ligue 1 · France |
| 2016-02-28 | HeraclesvRodaEredivisie · Netherlands | 0–5 | Eredivisie · Netherlands |
| 2016-02-28 | PalermovBolognaSerie A · Italy | 0–0 | Serie A · Italy |
| 2016-02-28 | GimnasticvValladolidLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2016-02-28 | AlmeriavAlbaceteLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2016-02-28 | Club LeonvChiapasLiga MX · Mexico | 1–3 | Liga MX · Mexico |
| 2016-02-28 | AstravDin. BucurestiSuperliga · Romania | 1–1 | Superliga · Romania |
| 2016-02-28 | VillarrealvLevanteLa Liga · Spain | 3–0 | La Liga · Spain |
| 2016-02-28 | Colon Santa FEvRosario CentralLiga Profesional · Argentina | 0–3 | Liga Profesional · Argentina |
| 2016-02-28 | LeganesvAlavesLa Liga 2 · Spain | 2–0 | La Liga 2 · Spain |
| 2016-02-28 | PatronatovBelgranoLiga Profesional · Argentina | 2–1 | Liga Profesional · Argentina |
| 2016-02-28 | GaziantepsporvGalatasaraySüper Lig · Turkey | 2–0 | Süper Lig · Turkey |
| 2016-02-28 | ConcordiavFC VoluntariSuperliga · Romania | 1–2 | Superliga · Romania |
| 2016-02-28 | La CorunavGranadaLa Liga · Spain | 0–1 | La Liga · Spain |
| 2016-02-28 | SalzburgvAustria ViennaBundesliga · Austria | 4–1 | Bundesliga · Austria |
| 2016-02-28 | St. GallenvLuganoSuper League · Switzerland | 3–3 | Super League · Switzerland |
| 2016-02-28 | FC CopenhagenvEsbjergSuperliga · Denmark | 2–1 | Superliga · Denmark |
| 2016-02-28 | LegiavRuchEkstraklasa · Poland | 2–0 | Ekstraklasa · Poland |
| 2016-02-28 | Lech PoznanvJagielloniaEkstraklasa · Poland | 0–2 | Ekstraklasa · Poland |
| 2016-02-28 | Pogon SzczecinvTermalica B-B.Ekstraklasa · Poland | 1–1 | Ekstraklasa · Poland |
| 2016-02-28 | SampdoriavFrosinoneSerie A · Italy | 2–0 | Serie A · Italy |
| 2016-02-28 | SK RapidvGrodigBundesliga · Austria | 3–2 | Bundesliga · Austria |
| 2016-02-28 | OviedovElcheLa Liga 2 · Spain | 3–0 | La Liga 2 · Spain |
| 2016-02-28 | VaduzvGrasshoppersSuper League · Switzerland | 1–1 | Super League · Switzerland |
| 2016-02-28 | CarpivAtalantaSerie A · Italy | 1–1 | Serie A · Italy |
| 2016-02-28 | BarcelonavSevillaLa Liga · Spain | 2–1 | La Liga · Spain |
| 2016-02-28 | Olimpo Bahia BlancavArsenal SarandiLiga Profesional · Argentina | 2–1 | Liga Profesional · Argentina |
| 2016-02-28 | Guadalajara ChivasvClub TijuanaLiga MX · Mexico | 1–1 | Liga MX · Mexico |
| 2016-02-28 | UtrechtvFeyenoordEredivisie · Netherlands | 1–2 | Eredivisie · Netherlands |
| 2016-02-28 | Ein FrankfurtvSchalke 04Bundesliga · Germany | 0–0 | Bundesliga · Germany |
| 2016-02-28 | MoreirensevTondelaPrimeira Liga · Portugal | 1–2 | Primeira Liga · Portugal |
| 2016-02-28 | ZaragozavLugoLa Liga 2 · Spain | 3–1 | La Liga 2 · Spain |