| 2021-03-17 | Avispa FukuokavKashima AntlersJ1 League · Japan | 1–0 | J1 League · Japan |
| 2021-03-17 | AccringtonvSunderlandLeague One · England | 0–2 | League One · England |
| 2021-03-17 | Viitorul ConstantavChindia TargovisteSuperliga · Romania | 0–0 | Superliga · Romania |
| 2021-03-17 | R. VolgogradvFK RostovPremier League · Russia | 0–4 | Premier League · Russia |
| 2021-03-17 | GrimsbyvTranmereLeague Two · England | 0–0 | League Two · England |
| 2021-03-17 | RegensburgvGreuther Furth2. Bundesliga · Germany | 1–2 | 2. Bundesliga · Germany |
| 2021-03-17 | TorinovSassuoloSerie A · Italy | 3–2 | Serie A · Italy |
| 2021-03-17 | Akhmat GroznyvArsenal TulaPremier League · Russia | 2–0 | Premier League · Russia |
| 2021-03-17 | FC TokyovShonan BellmareJ1 League · Japan | 3–2 | J1 League · Japan |
| 2021-03-17 | BirminghamvReadingChampionship · England | 2–1 | Championship · England |
| 2021-03-17 | CSKA MoscowvZenitPremier League · Russia | 2–3 | Premier League · Russia |
| 2021-03-17 | Nagoya GrampusvYokohama FCJ1 League · Japan | 3–0 | J1 League · Japan |
| 2021-03-17 | Yokohama F. MarinosvTokushimaJ1 League · Japan | 1–0 | J1 League · Japan |
| 2021-03-17 | Cerezo OsakavOita TrinitaJ1 League · Japan | 1–0 | J1 League · Japan |
| 2021-03-17 | SevillavElcheLa Liga · Spain | 2–0 | La Liga · Spain |
| 2021-03-17 | Vissel KobevKawasaki FrontaleJ1 League · Japan | 1–1 | J1 League · Japan |
| 2021-03-17 | WycombevBarnsleyChampionship · England | 1–3 | Championship · England |
| 2021-03-16 | BlackpoolvBurtonLeague One · England | 1–1 | League One · England |
| 2021-03-16 | DundeevAyrChampionship · Scotland | 1–3 | Championship · Scotland |
| 2021-03-16 | EmpolivPordenoneSerie B · Italy | 1–0 | Serie B · Italy |
| 2021-03-16 | Univ. CraiovavUTA AradSuperliga · Romania | 2–0 | Superliga · Romania |
| 2021-03-16 | Port ValevNewport CountyLeague Two · England | 2–1 | League Two · England |
| 2021-03-16 | Club LeonvNecaxaLiga MX · Mexico | 3–1 | Liga MX · Mexico |
| 2021-03-16 | CardiffvStokeChampionship · England | 0–0 | Championship · England |
| 2021-03-16 | DerbyvBrentfordChampionship · England | 2–2 | Championship · England |
| 2021-03-16 | ChievovFrosinoneSerie B · Italy | 0–0 | Serie B · Italy |
| 2021-03-16 | Kings LynnvHartlepoolNational League · England | 2–2 | National League · England |
| 2021-03-16 | ChesterfieldvSuttonNational League · England | 0–1 | National League · England |
| 2021-03-16 | AFC WimbledonvWiganLeague One · England | 1–1 | League One · England |
| 2021-03-16 | CharltonvBristol RvsLeague One · England | 3–2 | League One · England |
| 2021-03-16 | PescaravAscoliSerie B · Italy | 2–3 | Serie B · Italy |
| 2021-03-16 | ScunthorpevOldhamLeague Two · England | 1–1 | League Two · England |
| 2021-03-16 | CosenzavVicenzaSerie B · Italy | 1–1 | Serie B · Italy |
| 2021-03-16 | MansfieldvCarlisleLeague Two · England | 1–1 | League Two · England |
| 2021-03-16 | RotherhamvWatfordChampionship · England | 1–4 | Championship · England |
| 2021-03-16 | OxfordvDoncasterLeague One · England | 3–0 | League One · England |
| 2021-03-16 | BournemouthvSwanseaChampionship · England | 3–0 | Championship · England |
| 2021-03-16 | LincolnvGillinghamLeague One · England | 0–3 | League One · England |
| 2021-03-16 | LutonvCoventryChampionship · England | 2–0 | Championship · England |
| 2021-03-16 | WrexhamvEastleighNational League · England | 2–2 | National League · England |
| 2021-03-16 | VeneziavLecceSerie B · Italy | 2–3 | Serie B · Italy |
| 2021-03-16 | Crawley TownvWalsallLeague Two · England | 1–1 | League Two · England |
| 2021-03-16 | YeovilvBromleyNational League · England | 1–2 | National League · England |
| 2021-03-16 | Milton Keynes DonsvPlymouthLeague One · England | 2–1 | League One · England |
| 2021-03-16 | IndependientevSarmiento JuninCopa De La Liga Profesional · Argentina | 6–0 | Copa De La Liga Profesional · Argentina |
| 2021-03-16 | Boreham WoodvNotts CountyNational League · England | 2–2 | National League · England |
| 2021-03-16 | Virtus EntellavCremoneseSerie B · Italy | 0–2 | Serie B · Italy |
| 2021-03-16 | SalfordvColchesterLeague Two · England | 0–0 | League Two · England |
| 2021-03-16 | Fleetwood TownvIpswichLeague One · England | 2–0 | League One · England |
| 2021-03-16 | MiddlesbroughvPrestonChampionship · England | 2–0 | Championship · England |