| 2018-03-04 | Randers FCvNordsjaellandDanish Superliga · Denmark | 0–3 | Danish Superliga · Denmark |
| 2018-03-04 | Vancouver WhitecapsvCF MontrealMLS · United States | 2–1 | MLS · United States |
| 2018-03-04 | AEKvPanioniosSuper League Greece · Greece | 1–0 | Super League Greece · Greece |
| 2018-03-04 | Guadalajara ChivasvClub AmericaLiga MX · Mexico | 1–1 | Liga MX · Mexico |
| 2018-03-04 | LuganovYoung BoysSwiss Super League · Switzerland | 2–4 | Swiss Super League · Switzerland |
| 2018-03-04 | OlympiakosvPanathinaikosSuper League Greece · Greece | 1–1 | Super League Greece · Greece |
| 2018-03-04 | LevantevEspanolLaLiga · Spain | 1–1 | LaLiga · Spain |
| 2018-03-04 | Sevilla BvSp GijonLaLiga 2 · Spain | 0–1 | LaLiga 2 · Spain |
| 2018-03-04 | TondelavChavesPrimeira Liga · Portugal | 2–0 | Primeira Liga · Portugal |
| 2018-03-04 | HeidenheimvBielefeld2. Bundesliga · Germany | 2–2 | 2. Bundesliga · Germany |
| 2018-03-04 | ValenciavBetisLaLiga · Spain | 2–0 | LaLiga · Spain |
| 2018-03-04 | GimnasticvTenerifeLaLiga 2 · Spain | 1–2 | LaLiga 2 · Spain |
| 2018-03-04 | Shandong LunengvBeijing GuoanChinese Super League · China | 3–0 | Chinese Super League · China |
| 2018-03-04 | NecaxavSantos LagunaLiga MX · Mexico | 1–2 | Liga MX · Mexico |
| 2018-03-04 | GuimaraesvBelenensesPrimeira Liga · Portugal | 0–0 | Primeira Liga · Portugal |
| 2018-03-04 | Asteras TripolisvPAOKSuper League Greece · Greece | 3–2 | Super League Greece · Greece |
| 2018-03-04 | BraunschweigvRegensburg2. Bundesliga · Germany | 2–1 | 2. Bundesliga · Germany |
| 2018-03-04 | AntalyasporvSivassporSüper Lig · Türkiye | 1–4 | Süper Lig · Türkiye |
| 2018-03-04 | UfavDynamo MoscowRussian Premier League · Russia | 1–1 | Russian Premier League · Russia |
| 2018-03-04 | MarseillevNantesLigue 1 · France | 1–1 | Ligue 1 · France |
| 2018-03-04 | CaenvStrasbourgLigue 1 · France | 2–0 | Ligue 1 · France |
| 2018-03-04 | CracoviavArka GdyniaEkstraklasa · Poland | 2–1 | Ekstraklasa · Poland |
| 2018-03-04 | ZwollevVVV VenloEredivisie · Netherlands | 1–1 | Eredivisie · Netherlands |
| 2018-03-04 | Arsenal TulavAkhmat GroznyRussian Premier League · Russia | 1–0 | Russian Premier League · Russia |
| 2018-03-04 | Guizhou ZhichengvJiangsu SuningChinese Super League · China | 1–3 | Chinese Super League · China |
| 2018-03-04 | AarhusvFC CopenhagenDanish Superliga · Denmark | 0–1 | Danish Superliga · Denmark |
| 2018-03-04 | FenerbahcevAkhisar BelediyesporSüper Lig · Türkiye | 2–3 | Süper Lig · Türkiye |
| 2018-03-04 | HuescavAlmeriaLaLiga 2 · Spain | 2–2 | LaLiga 2 · Spain |
| 2018-03-04 | FreiburgvBayern MunichBundesliga · Germany | 0–4 | Bundesliga · Germany |
| 2018-03-04 | BlackburnvWiganLeague One · England | 2–2 | League One · England |
| 2018-03-04 | Lokomotiv MoscowvSpartak MoscowRussian Premier League · Russia | 0–0 | Russian Premier League · Russia |
| 2018-03-04 | Sparta RotterdamvDen HaagEredivisie · Netherlands | 2–1 | Eredivisie · Netherlands |
| 2018-03-04 | AlcorconvCordobaLaLiga 2 · Spain | 1–2 | LaLiga 2 · Spain |
| 2018-03-04 | FC DallasvReal Salt LakeMLS · United States | 1–1 | MLS · United States |
| 2018-03-04 | LegiavLech PoznanEkstraklasa · Poland | 2–1 | Ekstraklasa · Poland |
| 2018-03-04 | BanfieldvNewells Old BoysLiga Profesional · Argentina | 1–0 | Liga Profesional · Argentina |
| 2018-03-04 | Seattle SoundersvLos Angeles FCMLS · United States | 0–1 | MLS · United States |
| 2018-03-04 | MoreirensevPacos FerreiraPrimeira Liga · Portugal | 2–0 | Primeira Liga · Portugal |
| 2018-03-04 | Urawa RedsvSanfrecce HiroshimaJ1 League · Japan | 1–2 | J1 League · Japan |
| 2018-03-04 | ThunvSt. GallenSwiss Super League · Switzerland | 1–2 | Swiss Super League · Switzerland |
| 2018-03-04 | MontpelliervLyonLigue 1 · France | 1–1 | Ligue 1 · France |
| 2018-03-04 | San Jose EarthquakesvMinnesota UnitedMLS · United States | 3–2 | MLS · United States |
| 2018-03-04 | LorcavAlbaceteLaLiga 2 · Spain | 1–2 | LaLiga 2 · Spain |
| 2018-03-04 | FC KolnvStuttgartBundesliga · Germany | 2–3 | Bundesliga · Germany |
| 2018-03-04 | SKA KhabarovskvTosnoRussian Premier League · Russia | 0–1 | Russian Premier League · Russia |
| 2018-03-03 | Houston DynamovAtlanta UtdMLS · United States | 4–0 | MLS · United States |
| 2018-03-03 | PlataniasvLamiaSuper League Greece · Greece | 1–2 | Super League Greece · Greece |
| 2018-03-03 | Cruz AzulvQueretaroLiga MX · Mexico | 0–1 | Liga MX · Mexico |
| 2018-03-03 | NurnbergvGreuther Furth2. Bundesliga · Germany | 0–2 | 2. Bundesliga · Germany |
| 2018-03-03 | CarlislevGrimsbyLeague Two · England | 2–0 | League Two · England |