| 2016-03-06 | AZ AlkmaarvExcelsiorEredivisie · Netherlands | 2–0 | Eredivisie · Netherlands |
| 2016-03-06 | AlavesvZaragozaLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2016-03-06 | Chicago FirevNew York CityMLS · United States | 3–4 | MLS · United States |
| 2016-03-06 | Urawa RedsvIwataJ1 League · Japan | 1–2 | J1 League · Japan |
| 2016-03-06 | West BromvMan UnitedPremier League · England | 1–0 | Premier League · England |
| 2016-03-06 | AcademicavGuimaraesPrimeira Liga · Portugal | 2–0 | Primeira Liga · Portugal |
| 2016-03-06 | XanthivKallonisSuper League · Greece | 0–0 | Super League · Greece |
| 2016-03-06 | HamburgvHerthaBundesliga · Germany | 2–0 | Bundesliga · Germany |
| 2016-03-06 | Portland TimbersvColumbus CrewMLS · United States | 2–1 | MLS · United States |
| 2016-03-06 | LyonvGuingampLigue 1 · France | 5–1 | Ligue 1 · France |
| 2016-03-06 | U CraiovavFC VoluntariSuperliga · Romania | 3–0 | Superliga · Romania |
| 2016-03-06 | UNAM PumasvCruz AzulLiga MX · Mexico | 2–2 | Liga MX · Mexico |
| 2016-03-06 | QueretarovGuadalajara ChivasLiga MX · Mexico | 0–2 | Liga MX · Mexico |
| 2016-03-06 | KonyasporvTrabzonsporSüper Lig · Turkey | 2–0 | Süper Lig · Turkey |
| 2016-03-06 | KofuvGamba OsakaJ1 League · Japan | 0–1 | J1 League · Japan |
| 2016-03-06 | AldosivivTemperleyLiga Profesional · Argentina | 1–1 | Liga Profesional · Argentina |
| 2016-03-06 | Lechia GdanskvJagielloniaEkstraklasa · Poland | 5–1 | Ekstraklasa · Poland |
| 2016-03-06 | Akhisar BelediyesporvFenerbahceSüper Lig · Turkey | 0–3 | Süper Lig · Turkey |
| 2016-03-06 | Uniao MadeiravBelenensesPrimeira Liga · Portugal | 0–0 | Primeira Liga · Portugal |
| 2016-03-06 | BetisvGranadaLa Liga · Spain | 2–0 | La Liga · Spain |
| 2016-03-06 | BoavistavNacionalPrimeira Liga · Portugal | 0–1 | Primeira Liga · Portugal |
| 2016-03-06 | PanthrakikosvPAOKSuper League · Greece | 2–1 | Super League · Greece |
| 2016-03-06 | FrosinonevUdineseSerie A · Italy | 2–0 | Serie A · Italy |
| 2016-03-06 | PanathinaikosvAtromitosSuper League · Greece | 2–0 | Super League · Greece |
| 2016-03-06 | GenoavEmpoliSerie A · Italy | 1–0 | Serie A · Italy |
| 2016-03-06 | Crystal PalacevLiverpoolPremier League · England | 1–2 | Premier League · England |
| 2016-03-06 | MarseillevToulouseLigue 1 · France | 1–1 | Ligue 1 · France |
| 2016-03-06 | EsbjergvRanders FCSuperliga · Denmark | 1–0 | Superliga · Denmark |
| 2016-03-06 | FeyenoordvCambuurEredivisie · Netherlands | 3–1 | Eredivisie · Netherlands |
| 2016-03-06 | VeriavLevadeiakosSuper League · Greece | 0–0 | Super League · Greece |
| 2016-03-06 | Akhmat GroznyvLokomotiv MoscowPremier League · Russia | 2–1 | Premier League · Russia |
| 2016-03-06 | RennesvNantesLigue 1 · France | 4–1 | Ligue 1 · France |
| 2016-03-06 | KasimpasavAntalyasporSüper Lig · Turkey | 2–1 | Süper Lig · Turkey |
| 2016-03-06 | Nagoya GrampusvSanfrecce HiroshimaJ1 League · Japan | 1–1 | J1 League · Japan |
| 2016-03-06 | GalatasarayvBuyuksehyrSüper Lig · Turkey | 3–3 | Süper Lig · Turkey |
| 2016-03-06 | Willem IIvAjaxEredivisie · Netherlands | 0–4 | Eredivisie · Netherlands |
| 2016-03-06 | PueblavVeracruzLiga MX · Mexico | 1–1 | Liga MX · Mexico |
| 2016-03-06 | AltachvSK RapidBundesliga · Austria | 0–0 | Bundesliga · Austria |
| 2016-03-06 | BraunschweigvDuisburg2. Bundesliga · Germany | 1–1 | 2. Bundesliga · Germany |
| 2016-03-06 | FC DallasvPhiladelphia UnionMLS · United States | 2–0 | MLS · United States |
| 2016-03-06 | Din. BucurestivFCSBSuperliga · Romania | 1–1 | Superliga · Romania |
| 2016-03-06 | AtalantavJuventusSerie A · Italy | 0–2 | Serie A · Italy |
| 2016-03-06 | ValenciavAth MadridLa Liga · Spain | 1–3 | La Liga · Spain |
| 2016-03-06 | Chongqing Liangjiang AthleticvGuangzhou EvergrandeSuper League · China | 2–1 | Super League · China |
| 2016-03-06 | AlbacetevLeganesLa Liga 2 · Spain | 0–3 | La Liga 2 · Spain |
| 2016-03-06 | AarhusvFC CopenhagenSuperliga · Denmark | 0–0 | Superliga · Denmark |
| 2016-03-06 | IndependientevColon Santa FELiga Profesional · Argentina | 4–1 | Liga Profesional · Argentina |
| 2016-03-06 | ModenavLivornoSerie B · Italy | 1–0 | Serie B · Italy |
| 2016-03-06 | SetubalvMoreirensePrimeira Liga · Portugal | 0–1 | Primeira Liga · Portugal |
| 2016-03-06 | NijmegenvHeraclesEredivisie · Netherlands | 1–0 | Eredivisie · Netherlands |