| 2022-03-12 | BeneventovCrotoneSerie B · Italy | 3–1 | Serie B · Italy |
| 2022-03-12 | BoltonvPlymouthLeague One · England | 0–1 | League One · England |
| 2022-03-12 | SampdoriavJuventusSerie A · Italy | 1–3 | Serie A · Italy |
| 2022-03-12 | BrentfordvBurnleyPremier League · England | 2–0 | Premier League · England |
| 2022-03-12 | Bristol RvsvHarrogateLeague Two · England | 3–0 | League Two · England |
| 2022-03-12 | LeccevBresciaSerie B · Italy | 1–1 | Serie B · Italy |
| 2022-03-12 | TernanavCosenzaSerie B · Italy | 2–0 | Serie B · Italy |
| 2022-03-12 | Boreham WoodvChesterfieldNational League · England | 1–1 | National League · England |
| 2022-03-12 | Port ValevCrawley TownLeague Two · England | 4–1 | League Two · England |
| 2022-03-12 | AlmeriavLugoLa Liga 2 · Spain | 3–3 | La Liga 2 · Spain |
| 2022-03-12 | Inverness CvArbroathChampionship · Scotland | 3–0 | Championship · Scotland |
| 2022-03-12 | BelenensesvBoavistaPrimeira Liga · Portugal | 0–0 | Primeira Liga · Portugal |
| 2022-03-12 | HalifaxvDover AthleticNational League · England | 2–1 | National League · England |
| 2022-03-12 | AdmiravRiedBundesliga · Austria | 2–0 | Bundesliga · Austria |
| 2022-03-12 | GrenoblevRodezLigue 2 · France | 0–0 | Ligue 2 · France |
| 2022-03-12 | LevantevEspanolLa Liga · Spain | 1–1 | La Liga · Spain |
| 2022-03-12 | Shimizu S-PulsevCerezo OsakaJ1 League · Japan | 1–3 | J1 League · Japan |
| 2022-03-12 | GuingampvQuevilly RouenLigue 2 · France | 1–1 | Ligue 2 · France |
| 2022-03-12 | PlatensevPatronatoCopa De La Liga Profesional · Argentina | 1–2 | Copa De La Liga Profesional · Argentina |
| 2022-03-12 | ForfarvStirlingLeague Two · Scotland | 0–1 | League Two · Scotland |
| 2022-03-12 | FC TokyovSanfrecce HiroshimaJ1 League · Japan | 2–1 | J1 League · Japan |
| 2022-03-12 | AuxerrevSochauxLigue 2 · France | 3–2 | Ligue 2 · France |
| 2022-03-12 | AccringtonvCharltonLeague One · England | 2–1 | League One · England |
| 2022-03-12 | Sarmiento JuninvNewells Old BoysCopa De La Liga Profesional · Argentina | 2–2 | Copa De La Liga Profesional · Argentina |
| 2022-03-12 | MonterreyvMazatlan FCLiga MX · Mexico | 2–1 | Liga MX · Mexico |
| 2022-03-11 | Vissel KobevKashima AntlersJ1 League · Japan | 0–2 | J1 League · Japan |
| 2022-03-11 | Ath MadridvCadizLa Liga · Spain | 2–1 | La Liga · Spain |
| 2022-03-11 | Hansa RostockvHolstein Kiel2. Bundesliga · Germany | 3–2 | 2. Bundesliga · Germany |
| 2022-03-11 | Oud-Heverlee LeuvenvSt. GilloisePro League · Belgium | 1–4 | Pro League · Belgium |
| 2022-03-11 | UTA AradvAcademica ClinceniSuperliga · Romania | 3–0 | Superliga · Romania |
| 2022-03-11 | DroghedavSligo RoversPremier Division · Ireland | 0–3 | Premier Division · Ireland |
| 2022-03-11 | TranmerevMansfieldLeague Two · England | 3–2 | League Two · England |
| 2022-03-11 | Arsenal SarandivVelez SarsfieldCopa De La Liga Profesional · Argentina | 0–0 | Copa De La Liga Profesional · Argentina |
| 2022-03-11 | ParmavCittadellaSerie B · Italy | 1–1 | Serie B · Italy |
| 2022-03-11 | West BromvHuddersfieldChampionship · England | 2–2 | Championship · England |
| 2022-03-11 | ZaragozavFuenlabradaLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2022-03-11 | LecznavLegiaEkstraklasa · Poland | 0–1 | Ekstraklasa · Poland |
| 2022-03-11 | Univ. CraiovavFC ArgesSuperliga · Romania | 3–0 | Superliga · Romania |
| 2022-03-11 | CambuurvAjaxEredivisie · Netherlands | 2–3 | Eredivisie · Netherlands |
| 2022-03-11 | ShelbournevDundalkPremier Division · Ireland | 1–1 | Premier Division · Ireland |
| 2022-03-11 | DarmstadtvSandhausen2. Bundesliga · Germany | 1–1 | 2. Bundesliga · Germany |
| 2022-03-11 | LillevSt EtienneLigue 1 · France | 0–0 | Ligue 1 · France |
| 2022-03-11 | BenficavVizelaPrimeira Liga · Portugal | 1–1 | Primeira Liga · Portugal |
| 2022-03-11 | Shamrock RoversvBohemiansPremier Division · Ireland | 1–0 | Premier Division · Ireland |
| 2022-03-11 | NordsjaellandvSonderjyskeSuperliga · Denmark | 1–1 | Superliga · Denmark |
| 2022-03-11 | AyrvKilmarnockChampionship · Scotland | 1–3 | Championship · Scotland |
| 2022-03-11 | Termalica B-B.vZaglebieEkstraklasa · Poland | 0–2 | Ekstraklasa · Poland |
| 2022-03-11 | Finn HarpsvSt. PatricksPremier Division · Ireland | 0–2 | Premier Division · Ireland |
| 2022-03-10 | LeedsvAston VillaPremier League · England | 0–3 | Premier League · England |
| 2022-03-10 | SouthamptonvNewcastlePremier League · England | 1–2 | Premier League · England |