| 2022-03-13 | FC DallasvNashville SCMLS · United States | 2–0 | MLS · United States |
| 2022-03-13 | FiorentinavBolognaSerie A · Italy | 1–0 | Serie A · Italy |
| 2022-03-13 | BurgosvSociedad BLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2022-03-13 | AZ AlkmaarvTwenteEredivisie · Netherlands | 0–1 | Eredivisie · Netherlands |
| 2022-03-13 | DortmundvBielefeldBundesliga · Germany | 1–0 | Bundesliga · Germany |
| 2022-03-13 | VeronavNapoliSerie A · Italy | 1–2 | Serie A · Italy |
| 2022-03-13 | LyonvRennesLigue 1 · France | 2–4 | Ligue 1 · France |
| 2022-03-13 | Guadalajara ChivasvClub AmericaLiga MX · Mexico | 0–0 | Liga MX · Mexico |
| 2022-03-13 | SalzburgvSturm GrazBundesliga · Austria | 1–0 | Bundesliga · Austria |
| 2022-03-13 | BarcelonavOsasunaLa Liga · Spain | 4–0 | La Liga · Spain |
| 2022-03-13 | LanusvColon Santa FECopa De La Liga Profesional · Argentina | 1–1 | Copa De La Liga Profesional · Argentina |
| 2022-03-13 | ViborgvVejleSuperliga · Denmark | 2–0 | Superliga · Denmark |
| 2022-03-13 | JagielloniavWisla PlockEkstraklasa · Poland | 0–1 | Ekstraklasa · Poland |
| 2022-03-13 | SouthamptonvWatfordPremier League · England | 1–2 | Premier League · England |
| 2022-03-13 | MidtjyllandvFC CopenhagenSuperliga · Denmark | 0–1 | Superliga · Denmark |
| 2022-03-13 | River PlatevGimnasia L.P.Copa De La Liga Profesional · Argentina | 4–0 | Copa De La Liga Profesional · Argentina |
| 2022-03-13 | HeraclesvVitesseEredivisie · Netherlands | 0–0 | Eredivisie · Netherlands |
| 2022-03-13 | Sp GijonvTenerifeLa Liga 2 · Spain | 1–2 | La Liga 2 · Spain |
| 2022-03-13 | Ad. DemirsporvSivassporSüper Lig · Turkey | 2–3 | Süper Lig · Turkey |
| 2022-03-13 | PAOKvGianninaSuper League · Greece | 1–0 | Super League · Greece |
| 2022-03-13 | TorinovInterSerie A · Italy | 1–1 | Serie A · Italy |
| 2022-03-13 | AngersvReimsLigue 1 · France | 0–1 | Ligue 1 · France |
| 2022-03-13 | Spartak MoscowvKrasnodarPremier League · Russia | 1–2 | Premier League · Russia |
| 2022-03-13 | PisavCremoneseSerie B · Italy | 3–0 | Serie B · Italy |
| 2022-03-13 | SociedadvAlavesLa Liga · Spain | 1–0 | La Liga · Spain |
| 2022-03-13 | LeverkusenvFC KolnBundesliga · Germany | 0–1 | Bundesliga · Germany |
| 2022-03-13 | Atlanta UtdvCharlotteMLS · United States | 2–1 | MLS · United States |
| 2022-03-13 | EvertonvWolvesPremier League · England | 0–1 | Premier League · England |
| 2022-03-13 | Randers FCvSilkeborgSuperliga · Denmark | 2–1 | Superliga · Denmark |
| 2022-03-13 | LASKvTirolBundesliga · Austria | 6–0 | Bundesliga · Austria |
| 2022-03-12 | AmiensvNancyLigue 2 · France | 1–0 | Ligue 2 · France |
| 2022-03-12 | StevenagevNewport CountyLeague Two · England | 0–2 | League Two · England |
| 2022-03-12 | WealdstonevWeymouthNational League · England | 3–2 | National League · England |
| 2022-03-12 | FamalicaovSanta ClaraPrimeira Liga · Portugal | 0–0 | Primeira Liga · Portugal |
| 2022-03-12 | BournemouthvDerbyChampionship · England | 2–0 | Championship · England |
| 2022-03-12 | IpswichvPortsmouthLeague One · England | 0–0 | League One · England |
| 2022-03-12 | DresdenvSt Pauli2. Bundesliga · Germany | 1–1 | 2. Bundesliga · Germany |
| 2022-03-12 | CoventryvSheffield UnitedChampionship · England | 4–1 | Championship · England |
| 2022-03-12 | RochdalevBarrowLeague Two · England | 0–0 | League Two · England |
| 2022-03-12 | GroningenvNijmegenEredivisie · Netherlands | 4–3 | Eredivisie · Netherlands |
| 2022-03-12 | East FifevDumbartonLeague One · Scotland | 2–0 | League One · Scotland |
| 2022-03-12 | Forest GreenvBradfordLeague Two · England | 0–2 | League Two · England |
| 2022-03-12 | M'gladbachvHerthaBundesliga · Germany | 2–0 | Bundesliga · Germany |
| 2022-03-12 | PeterheadvMontroseLeague One · Scotland | 0–1 | League One · Scotland |
| 2022-03-12 | HartlepoolvLeyton OrientLeague Two · England | 0–0 | League Two · England |
| 2022-03-12 | ShrewsburyvOxfordLeague One · England | 1–2 | League One · England |
| 2022-03-12 | VillarrealvCeltaLa Liga · Spain | 1–0 | La Liga · Spain |
| 2022-03-12 | CardiffvPrestonChampionship · England | 0–0 | Championship · England |
| 2022-03-12 | ExetervSalfordLeague Two · England | 0–0 | League Two · England |
| 2022-03-12 | SunderlandvCreweLeague One · England | 2–0 | League One · England |