| 2000-11-19 | Sp LisbonvBoavistaPrimeira Liga · Portugal | 0–0 | Primeira Liga · Portugal |
| 2000-11-19 | CittadellavTrevisoSerie B · Italy | 2–2 | Serie B · Italy |
| 2000-11-19 | OberhausenvSt Pauli2. Bundesliga · Germany | 2–3 | 2. Bundesliga · Germany |
| 2000-11-19 | FenerbahcevTrabzonsporSüper Lig · Turkey | 5–2 | Süper Lig · Turkey |
| 2000-11-19 | AnconavGenoaSerie B · Italy | 1–0 | Serie B · Italy |
| 2000-11-19 | NapolivAtalantaSerie A · Italy | 0–0 | Serie A · Italy |
| 2000-11-19 | ElchevGetafeLa Liga 2 · Spain | 1–4 | La Liga 2 · Spain |
| 2000-11-19 | OviedovValladolidLa Liga · Spain | 4–1 | La Liga · Spain |
| 2000-11-19 | Gil VicentevLeiriaPrimeira Liga · Portugal | 2–0 | Primeira Liga · Portugal |
| 2000-11-19 | BochumvDortmundBundesliga · Germany | 1–1 | Bundesliga · Germany |
| 2000-11-19 | SociedadvNumanciaLa Liga · Spain | 4–1 | La Liga · Spain |
| 2000-11-19 | NAC BredavAjaxEredivisie · Netherlands | 0–3 | Eredivisie · Netherlands |
| 2000-11-19 | BetisvSevillaLa Liga 2 · Spain | 1–3 | La Liga 2 · Spain |
| 2000-11-19 | SalgueirosvBeira MarPrimeira Liga · Portugal | 0–1 | Primeira Liga · Portugal |
| 2000-11-19 | CordobavExtremaduraLa Liga 2 · Spain | 2–0 | La Liga 2 · Spain |
| 2000-11-19 | BadajozvMurciaLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2000-11-19 | CeltavSantanderLa Liga · Spain | 1–1 | La Liga · Spain |
| 2000-11-19 | OlympiakosvPanahaikiSuper League · Greece | 3–0 | Super League · Greece |
| 2000-11-19 | ArisvAthinaikosSuper League · Greece | 2–0 | Super League · Greece |
| 2000-11-19 | LevantevSp GijonLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2000-11-19 | Greuther FurthvStuttgarter K2. Bundesliga · Germany | 2–0 | 2. Bundesliga · Germany |
| 2000-11-19 | HarelbekevSt TruidenPro League · Belgium | 0–4 | Pro League · Belgium |
| 2000-11-19 | UdinesevRegginaSerie A · Italy | 3–0 | Serie A · Italy |
| 2000-11-19 | FerrolvSalamancaLa Liga 2 · Spain | 0–1 | La Liga 2 · Spain |
| 2000-11-19 | LeccevBariSerie A · Italy | 2–0 | Serie A · Italy |
| 2000-11-19 | TottenhamvLiverpoolPremier League · England | 2–1 | Premier League · England |
| 2000-11-19 | RavennavTernanaSerie B · Italy | 2–2 | Serie B · Italy |
| 2000-11-19 | DenizlisporvGenclerbirligiSüper Lig · Turkey | 0–0 | Süper Lig · Turkey |
| 2000-11-19 | TorinovCrotoneSerie B · Italy | 1–0 | Serie B · Italy |
| 2000-11-19 | ChemnitzvReutlingen2. Bundesliga · Germany | 1–3 | 2. Bundesliga · Germany |
| 2000-11-19 | CampomaiorensevSp BragaPrimeira Liga · Portugal | 1–1 | Primeira Liga · Portugal |
| 2000-11-19 |  Ivory Coastv LibyaAfrican Cup of Nations qualification | 2–1 | African Cup of Nations qualification |
| 2000-11-19 | AntwerpvGerminalPro League · Belgium | 1–2 | Pro League · Belgium |
| 2000-11-19 | SampdoriavChievoSerie B · Italy | 1–1 | Serie B · Italy |
| 2000-11-19 | JaenvLeganesLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2000-11-19 | FiorentinavVicenzaSerie A · Italy | 3–2 | Serie A · Italy |
| 2000-11-19 | AlvercavEst AmadoraPrimeira Liga · Portugal | 3–1 | Primeira Liga · Portugal |
| 2000-11-19 | KalamatavAEKSuper League · Greece | 3–1 | Super League · Greece |
| 2000-11-19 | AuxerrevStrasbourgLigue 1 · France | 1–2 | Ligue 1 · France |
| 2000-11-19 | UnterhachingvCottbusBundesliga · Germany | 2–1 | Bundesliga · Germany |
| 2000-11-19 | BolognavParmaSerie A · Italy | 2–1 | Serie A · Italy |
| 2000-11-19 | CosenzavSalernitanaSerie B · Italy | 1–0 | Serie B · Italy |
| 2000-11-19 | VeneziavCagliariSerie B · Italy | 2–2 | Serie B · Italy |
| 2000-11-19 | XanthivPaniliakosSuper League · Greece | 2–0 | Super League · Greece |
| 2000-11-19 | ZaragozavBarcelonaLa Liga · Spain | 3–1 | La Liga · Spain |
| 2000-11-19 | M'gladbachvDuisburg2. Bundesliga · Germany | 1–1 | 2. Bundesliga · Germany |
| 2000-11-19 | VallecanovMalagaLa Liga · Spain | 4–2 | La Liga · Spain |
| 2000-11-19 | MaritimovPacos FerreiraPrimeira Liga · Portugal | 1–1 | Primeira Liga · Portugal |
| 2000-11-19 | CompostelavLleidaLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2000-11-19 | AvesvPortoPrimeira Liga · Portugal | 0–1 | Primeira Liga · Portugal |