| 2021-04-07 | Shonan BellmarevNagoya GrampusJ1 League · Japan | 0–0 | J1 League · Japan |
| 2021-04-07 | TokushimavVegalta SendaiJ1 League · Japan | 1–0 | J1 League · Japan |
| 2021-04-07 | BesiktasvAlanyasporSüper Lig · Turkey | 3–0 | Süper Lig · Turkey |
| 2021-04-07 | JuventusvNapoliSerie A · Italy | 2–1 | Serie A · Italy |
| 2021-04-07 | Kashima AntlersvKashiwa ReysolJ1 League · Japan | 2–1 | J1 League · Japan |
| 2021-04-07 | SociedadvAth BilbaoLa Liga · Spain | 1–1 | La Liga · Spain |
| 2021-04-06 | HeidenheimvHolstein Kiel2. Bundesliga · Germany | 1–0 | 2. Bundesliga · Germany |
| 2021-04-06 | MortonvInverness CChampionship · Scotland | 1–4 | Championship · Scotland |
| 2021-04-06 | MorecambevSouthendLeague Two · England | 1–1 | League Two · England |
| 2021-04-06 | Airdrie UtdvFalkirkLeague One · Scotland | 2–1 | League One · Scotland |
| 2021-04-06 | LyngbyvVejleSuperliga · Denmark | 0–0 | Superliga · Denmark |
| 2021-04-06 | BrentfordvBirminghamChampionship · England | 0–0 | Championship · England |
| 2021-04-06 | Queens ParkvCowdenbeathLeague Two · Scotland | 3–0 | League Two · Scotland |
| 2021-04-06 | East FifevPartickLeague One · Scotland | 2–2 | League One · Scotland |
| 2021-04-06 | AyrvDundeeChampionship · Scotland | 0–3 | Championship · Scotland |
| 2021-04-06 | NorwichvHuddersfieldChampionship · England | 7–0 | Championship · England |
| 2021-04-06 | StirlingvAlbion RvsLeague Two · Scotland | 1–1 | League Two · Scotland |
| 2021-04-06 | TrabzonsporvKayserisporSüper Lig · Turkey | 1–1 | Süper Lig · Turkey |
| 2021-04-06 | KaragumrukvHataysporSüper Lig · Turkey | 1–0 | Süper Lig · Turkey |
| 2021-04-06 | Edinburgh CityvAnnan AthleticLeague Two · Scotland | 1–1 | League Two · Scotland |
| 2021-04-06 | Waasland-BeverenvSt TruidenPro League · Belgium | 2–4 | Pro League · Belgium |
| 2021-04-06 | DumbartonvMontroseLeague One · Scotland | 0–0 | League One · Scotland |
| 2021-04-06 | BanfieldvEstudiantes L.P.Copa De La Liga Profesional · Argentina | 2–2 | Copa De La Liga Profesional · Argentina |
| 2021-04-06 | ElginvStranraerLeague Two · Scotland | 2–1 | League Two · Scotland |
| 2021-04-06 | ClydevCove RangersLeague One · Scotland | 1–1 | League One · Scotland |
| 2021-04-06 | GoztepvRizesporSüper Lig · Turkey | 2–0 | Süper Lig · Turkey |
| 2021-04-06 | ForfarvPeterheadLeague One · Scotland | 1–1 | League One · Scotland |
| 2021-04-06 | Yokohama F. MarinosvCerezo OsakaJ1 League · Japan | 1–0 | J1 League · Japan |
| 2021-04-06 | CarlislevScunthorpeLeague Two · England | 2–0 | League Two · England |
| 2021-04-06 | BrechinvStenhousemuirLeague Two · Scotland | 1–1 | League Two · Scotland |
| 2021-04-05 | ReadingvDerbyChampionship · England | 3–1 | Championship · England |
| 2021-04-05 | HalifaxvWeymouthNational League · England | 3–2 | National League · England |
| 2021-04-05 | JagielloniavSlask WroclawEkstraklasa · Poland | 0–1 | Ekstraklasa · Poland |
| 2021-04-05 | ColchestervBarrowLeague Two · England | 1–1 | League Two · England |
| 2021-04-05 | MidtjyllandvBrondbySuperliga · Denmark | 1–0 | Superliga · Denmark |
| 2021-04-05 | EvertonvCrystal PalacePremier League · England | 1–1 | Premier League · England |
| 2021-04-05 | Oud-Heverlee LeuvenvGenkPro League · Belgium | 2–3 | Pro League · Belgium |
| 2021-04-05 | Newport CountyvBoltonLeague Two · England | 1–0 | League Two · England |
| 2021-04-05 | SpalvVeneziaSerie B · Italy | 1–1 | Serie B · Italy |
| 2021-04-05 | StevenagevBradfordLeague Two · England | 1–1 | League Two · England |
| 2021-04-05 | AFC WimbledonvFleetwood TownLeague One · England | 0–1 | League One · England |
| 2021-04-05 | BlackpoolvGillinghamLeague One · England | 4–1 | League One · England |
| 2021-04-05 | Dag and RedvAldershotNational League · England | 0–2 | National League · England |
| 2021-04-05 | CittadellavRegginaSerie B · Italy | 1–1 | Serie B · Italy |
| 2021-04-05 | ExetervMansfieldLeague Two · England | 0–0 | League Two · England |
| 2021-04-05 | Racing ClubvGodoy CruzCopa De La Liga Profesional · Argentina | 2–4 | Copa De La Liga Profesional · Argentina |
| 2021-04-05 | ShrewsburyvPlymouthLeague One · England | 3–0 | League One · England |
| 2021-04-05 | QueretarovTigres UANLLiga MX · Mexico | 0–1 | Liga MX · Mexico |
| 2021-04-05 | PodbeskidzievWislaEkstraklasa · Poland | 2–0 | Ekstraklasa · Poland |
| 2021-04-05 | MoreirensevSp LisbonPrimeira Liga · Portugal | 1–1 | Primeira Liga · Portugal |