| 2022-03-22 | Kings LynnvStockportNational League · England | 0–3 | National League · England |
| 2022-03-22 | Notts CountyvBoreham WoodNational League · England | 1–0 | National League · England |
| 2022-03-22 | OldhamvSuttonLeague Two · England | 1–3 | League Two · England |
| 2022-03-22 | YeovilvBromleyNational League · England | 2–1 | National League · England |
| 2022-03-22 | AltrinchamvChesterfieldNational League · England | 1–0 | National League · England |
| 2022-03-22 | PlymouthvCheltenhamLeague One · England | 2–0 | League One · England |
| 2022-03-22 | WrexhamvHalifaxNational League · England | 3–1 | National League · England |
| 2022-03-22 | Atl. TucumanvCentral CordobaCopa De La Liga Profesional · Argentina | 0–1 | Copa De La Liga Profesional · Argentina |
| 2022-03-22 | DunfermlinevPartickChampionship · Scotland | 4–1 | Championship · Scotland |
| 2022-03-22 | Port ValevExeterLeague Two · England | 0–0 | League Two · England |
| 2022-03-22 | EastleighvDag and RedNational League · England | 0–1 | National League · England |
| 2022-03-22 | MaidenheadvSouthendNational League · England | 2–1 | National League · England |
| 2022-03-22 | GrimsbyvSolihullNational League · England | 1–2 | National League · England |
| 2022-03-22 | TorquayvAldershotNational League · England | 4–0 | National League · England |
| 2022-03-22 | HarrogatevLeyton OrientLeague Two · England | 0–3 | League Two · England |
| 2022-03-21 | Mazatlan FCvClub LeonLiga MX · Mexico | 1–2 | Liga MX · Mexico |
| 2022-03-21 | AtlasvGuadalajara ChivasLiga MX · Mexico | 1–1 | Liga MX · Mexico |
| 2022-03-21 | Club TijuanavJuarezLiga MX · Mexico | 1–0 | Liga MX · Mexico |
| 2022-03-21 | Los Angeles FCvVancouver WhitecapsMLS · United States | 3–1 | MLS · United States |
| 2022-03-21 | ColchestervForest GreenLeague Two · England | 0–1 | League Two · England |
| 2022-03-21 |  New Zealandv FijiFIFA World Cup qualification | 4–0 | FIFA World Cup qualification |
| 2022-03-21 | MiovenivChindia TargovisteSuperliga · Romania | 1–0 | Superliga · Romania |
| 2022-03-21 | TenerifevAlmeriaLa Liga 2 · Spain | 0–1 | La Liga 2 · Spain |
| 2022-03-21 |  Papua New Guineav New CaledoniaFIFA World Cup qualification | 1–0 | FIFA World Cup qualification |
| 2022-03-21 | Defensa y JusticiavArsenal SarandiCopa De La Liga Profesional · Argentina | 1–1 | Copa De La Liga Profesional · Argentina |
| 2022-03-20 | TottenhamvWest HamPremier League · England | 3–1 | Premier League · England |
| 2022-03-20 | SpalvCremoneseSerie B · Italy | 0–2 | Serie B · Italy |
| 2022-03-20 | Minnesota UnitedvSan Jose EarthquakesMLS · United States | 1–0 | MLS · United States |
| 2022-03-20 | Real Salt LakevNashville SCMLS · United States | 2–1 | MLS · United States |
| 2022-03-20 | LeicestervBrentfordPremier League · England | 2–1 | Premier League · England |
| 2022-03-20 | AEKvPAOKSuper League · Greece | 0–1 | Super League · Greece |
| 2022-03-20 | CadizvVillarrealLa Liga · Spain | 1–0 | La Liga · Spain |
| 2022-03-20 | Gil VicentevMaritimoPrimeira Liga · Portugal | 1–1 | Primeira Liga · Portugal |
| 2022-03-20 | NurnbergvDresden2. Bundesliga · Germany | 1–1 | 2. Bundesliga · Germany |
| 2022-03-20 | Houston DynamovColorado RapidsMLS · United States | 1–1 | MLS · United States |
| 2022-03-20 | AjaxvFeyenoordEredivisie · Netherlands | 3–2 | Eredivisie · Netherlands |
| 2022-03-20 | CracoviavPiast GliwiceEkstraklasa · Poland | 0–1 | Ekstraklasa · Poland |
| 2022-03-20 | Austin FCvSeattle SoundersMLS · United States | 1–1 | MLS · United States |
| 2022-03-20 | Sturm GrazvA. KlagenfurtBundesliga · Austria | 3–1 | Bundesliga · Austria |
| 2022-03-20 | SevillavSociedadLa Liga · Spain | 0–0 | La Liga · Spain |
| 2022-03-20 | PachucavCruz AzulLiga MX · Mexico | 1–0 | Liga MX · Mexico |
| 2022-03-20 | ServettevSionSuper League · Switzerland | 2–1 | Super League · Switzerland |
| 2022-03-20 | FC ArgesvFCSBSuperliga · Romania | 2–3 | Superliga · Romania |
| 2022-03-20 | GianninavOlympiakosSuper League · Greece | 1–1 | Super League · Greece |
| 2022-03-20 | LuganovLausanneSuper League · Switzerland | 3–1 | Super League · Switzerland |
| 2022-03-20 | ReimsvLyonLigue 1 · France | 0–0 | Ligue 1 · France |
| 2022-03-20 | QPRvPeterboroChampionship · England | 1–3 | Championship · England |
| 2022-03-20 | EmpolivVeronaSerie A · Italy | 1–1 | Serie A · Italy |
| 2022-03-20 | VicenzavAscoliSerie B · Italy | 2–0 | Serie B · Italy |
| 2022-03-20 | CeltavBetisLa Liga · Spain | 0–0 | La Liga · Spain |