| 2022-04-11 | AntalyasporvHataysporSüper Lig · Turkey | 4–1 | Süper Lig · Turkey |
| 2022-04-11 | VejlevViborgSuperliga · Denmark | 2–2 | Superliga · Denmark |
| 2022-04-11 | FCSBvFC VoluntariSuperliga · Romania | 4–0 | Superliga · Romania |
| 2022-04-11 | VallecanovValenciaLa Liga · Spain | 1–1 | La Liga · Spain |
| 2022-04-10 | RosenborgvOddEliteserien · Norway | 1–0 | Eliteserien · Norway |
| 2022-04-10 | Sanfrecce HiroshimavAvispa FukuokaJ1 League · Japan | 1–0 | J1 League · Japan |
| 2022-04-10 | MirandesvBurgosLa Liga 2 · Spain | 3–1 | La Liga 2 · Spain |
| 2022-04-10 | FC BotosanivSepsi Sf. GheorgheSuperliga · Romania | 0–1 | Superliga · Romania |
| 2022-04-10 | Univ. CraiovavCFR ClujSuperliga · Romania | 3–2 | Superliga · Romania |
| 2022-04-10 | Holstein KielvHamburg2. Bundesliga · Germany | 1–0 | 2. Bundesliga · Germany |
| 2022-04-10 | HelsingborgvGoteborgAllsvenskan · Sweden | 0–1 | Allsvenskan · Sweden |
| 2022-04-10 | RakowvSlask WroclawEkstraklasa · Poland | 1–1 | Ekstraklasa · Poland |
| 2022-04-10 | TromsovHam-KamEliteserien · Norway | 2–1 | Eliteserien · Norway |
| 2022-04-10 | A. KlagenfurtvSalzburgBundesliga · Austria | 0–6 | Bundesliga · Austria |
| 2022-04-10 | Ad. DemirsporvAltaySüper Lig · Turkey | 3–1 | Süper Lig · Turkey |
| 2022-04-10 | MjallbyvDjurgardenAllsvenskan · Sweden | 1–0 | Allsvenskan · Sweden |
| 2022-04-10 | PatronatovBanfieldCopa De La Liga Profesional · Argentina | 0–1 | Copa De La Liga Profesional · Argentina |
| 2022-04-10 | Sporting Kansas CityvNashville SCMLS · United States | 1–2 | MLS · United States |
| 2022-04-10 | Shimizu S-PulsevGamba OsakaJ1 League · Japan | 1–1 | J1 League · Japan |
| 2022-04-10 | PlatensevRacing ClubCopa De La Liga Profesional · Argentina | 0–1 | Copa De La Liga Profesional · Argentina |
| 2022-04-10 | AEKvArisSuper League · Greece | 1–2 | Super League · Greece |
| 2022-04-10 | RomavSalernitanaSerie A · Italy | 2–1 | Serie A · Italy |
| 2022-04-10 | NorwichvBurnleyPremier League · England | 2–0 | Premier League · England |
| 2022-04-10 | FC TokyovUrawa RedsJ1 League · Japan | 0–0 | J1 League · Japan |
| 2022-04-10 | Estudiantes L.P.vCentral CordobaCopa De La Liga Profesional · Argentina | 5–0 | Copa De La Liga Profesional · Argentina |
| 2022-04-10 | Shonan BellmarevIwataJ1 League · Japan | 0–0 | J1 League · Japan |
| 2022-04-10 | Santa ClaravEstorilPrimeira Liga · Portugal | 2–0 | Primeira Liga · Portugal |
| 2022-04-10 | SonderjyskevOdenseSuperliga · Denmark | 2–2 | Superliga · Denmark |
| 2022-04-10 | HeerenveenvGroningenEredivisie · Netherlands | 3–1 | Eredivisie · Netherlands |
| 2022-04-10 | KortrijkvAnderlechtPro League · Belgium | 2–3 | Pro League · Belgium |
| 2022-04-10 | BochumvLeverkusenBundesliga · Germany | 0–0 | Bundesliga · Germany |
| 2022-04-10 | Vancouver WhitecapsvPortland TimbersMLS · United States | 2–3 | MLS · United States |
| 2022-04-10 | SivassporvBuyuksehyrSüper Lig · Turkey | 0–2 | Süper Lig · Turkey |
| 2022-04-10 | AngersvLilleLigue 1 · France | 1–1 | Ligue 1 · France |
| 2022-04-10 | NapolivFiorentinaSerie A · Italy | 2–3 | Serie A · Italy |
| 2022-04-10 | ServettevZurichSuper League · Switzerland | 1–0 | Super League · Switzerland |
| 2022-04-10 | GianninavPanathinaikosSuper League · Greece | 0–0 | Super League · Greece |
| 2022-04-10 | Real Salt LakevToronto FCMLS · United States | 2–2 | MLS · United States |
| 2022-04-10 | BeneventovVicenzaSerie B · Italy | 1–0 | Serie B · Italy |
| 2022-04-10 | TolucavGuadalajara ChivasLiga MX · Mexico | 1–1 | Liga MX · Mexico |
| 2022-04-10 | Velez SarsfieldvBoca JuniorsCopa De La Liga Profesional · Argentina | 0–0 | Copa De La Liga Profesional · Argentina |
| 2022-04-10 | River PlatevArgentinos JrsCopa De La Liga Profesional · Argentina | 4–2 | Copa De La Liga Profesional · Argentina |
| 2022-04-10 | BrestvNantesLigue 1 · France | 1–1 | Ligue 1 · France |
| 2022-04-10 | St. GallenvBaselSuper League · Switzerland | 2–2 | Super League · Switzerland |
| 2022-04-10 | AIKvNorrkopingAllsvenskan · Sweden | 1–0 | Allsvenskan · Sweden |
| 2022-04-10 | Vissel KobevCerezo OsakaJ1 League · Japan | 0–1 | J1 League · Japan |
| 2022-04-10 | CharleroivWaregemPro League · Belgium | 3–0 | Pro League · Belgium |
| 2022-04-10 | ValerengavHaugesundEliteserien · Norway | 2–1 | Eliteserien · Norway |
| 2022-04-10 | HeraclesvFeyenoordEredivisie · Netherlands | 1–4 | Eredivisie · Netherlands |
| 2022-04-10 | FuenlabradavHuescaLa Liga 2 · Spain | 2–3 | La Liga 2 · Spain |