| 2016-04-19 | WalsallvSwindonLeague One · England | 1–1 | League One · England |
| 2016-04-18 | Poli IasivPoli TimisoaraSuperliga · Romania | 0–0 | Superliga · Romania |
| 2016-04-18 | DijonvParis FCLigue 2 · France | 3–0 | Ligue 2 · France |
| 2016-04-18 | StokevTottenhamPremier League · England | 0–4 | Premier League · England |
| 2016-04-18 | BenficavSetubalPrimeira Liga · Portugal | 2–1 | Primeira Liga · Portugal |
| 2016-04-18 | CesenavCrotoneSerie B · Italy | 2–1 | Serie B · Italy |
| 2016-04-18 | Viitorul ConstantavPanduriiSuperliga · Romania | 0–2 | Superliga · Romania |
| 2016-04-18 | HJKvSJKVeikkausliiga · Finland | 2–1 | Veikkausliiga · Finland |
| 2016-04-18 | Inter TurkuvKuPSVeikkausliiga · Finland | 3–1 | Veikkausliiga · Finland |
| 2016-04-18 | UralvRubin KazanPremier League · Russia | 0–1 | Premier League · Russia |
| 2016-04-18 | GenclerbirligivTrabzonsporSüper Lig · Turkey | 3–1 | Süper Lig · Turkey |
| 2016-04-18 | LahtivHIFKVeikkausliiga · Finland | 2–2 | Veikkausliiga · Finland |
| 2016-04-18 | ElfsborgvMalmo FFAllsvenskan · Sweden | 0–1 | Allsvenskan · Sweden |
| 2016-04-18 | FC DallasvSporting Kansas CityMLS · United States | 2–1 | MLS · United States |
| 2016-04-18 | PatronatovBanfieldLiga Profesional · Argentina | 0–2 | Liga Profesional · Argentina |
| 2016-04-18 | Sp BragavTondelaPrimeira Liga · Portugal | 3–0 | Primeira Liga · Portugal |
| 2016-04-18 | SundsvallvOrebroAllsvenskan · Sweden | 3–1 | Allsvenskan · Sweden |
| 2016-04-18 | BraunschweigvFreiburg2. Bundesliga · Germany | 2–2 | 2. Bundesliga · Germany |
| 2016-04-18 | EsbjergvMidtjyllandSuperliga · Denmark | 0–2 | Superliga · Denmark |
| 2016-04-18 | Arsenal SarandivBelgranoLiga Profesional · Argentina | 3–3 | Liga Profesional · Argentina |
| 2016-04-18 | Olimpo Bahia BlancavRiver PlateLiga Profesional · Argentina | 0–1 | Liga Profesional · Argentina |
| 2016-04-17 | Ath MadridvGranadaLa Liga · Spain | 3–0 | La Liga · Spain |
| 2016-04-17 | AalborgvSonderjyskeSuperliga · Denmark | 1–2 | Superliga · Denmark |
| 2016-04-17 | Club LeonvPueblaLiga MX · Mexico | 4–1 | Liga MX · Mexico |
| 2016-04-17 | SevillavLa CorunaLa Liga · Spain | 1–1 | La Liga · Spain |
| 2016-04-17 | AalesundvVikingEliteserien · Norway | 1–2 | Eliteserien · Norway |
| 2016-04-17 | SK RapidvAustria ViennaBundesliga · Austria | 1–0 | Bundesliga · Austria |
| 2016-04-17 | Willem IIvDen HaagEredivisie · Netherlands | 0–2 | Eredivisie · Netherlands |
| 2016-04-17 | PK-35 VantaavVPSVeikkausliiga · Finland | 0–2 | Veikkausliiga · Finland |
| 2016-04-17 | TenerifevAlbaceteLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2016-04-17 | LuganovThunSuper League · Switzerland | 2–1 | Super League · Switzerland |
| 2016-04-17 | BelenensesvAcademicaPrimeira Liga · Portugal | 1–1 | Primeira Liga · Portugal |
| 2016-04-17 | San LorenzovRosario CentralLiga Profesional · Argentina | 2–1 | Liga Profesional · Argentina |
| 2016-04-17 | HuescavCordobaLa Liga 2 · Spain | 0–2 | La Liga 2 · Spain |
| 2016-04-17 | BursasporvAkhisar BelediyesporSüper Lig · Turkey | 0–2 | Süper Lig · Turkey |
| 2016-04-17 | PodbeskidzievTermalica B-B.Ekstraklasa · Poland | 0–1 | Ekstraklasa · Poland |
| 2016-04-17 | UdinesevChievoSerie A · Italy | 0–0 | Serie A · Italy |
| 2016-04-17 | ExcelsiorvHeerenveenEredivisie · Netherlands | 1–1 | Eredivisie · Netherlands |
| 2016-04-17 | BarcelonavValenciaLa Liga · Spain | 1–2 | La Liga · Spain |
| 2016-04-17 | Tigres UANLvDorados de SinaloaLiga MX · Mexico | 5–2 | Liga MX · Mexico |
| 2016-04-17 | NijmegenvCambuurEredivisie · Netherlands | 2–1 | Eredivisie · Netherlands |
| 2016-04-17 | JuventusvPalermoSerie A · Italy | 4–0 | Serie A · Italy |
| 2016-04-17 | HebeivShijiazhuangSuper League · China | 1–1 | Super League · China |
| 2016-04-17 | ChiapasvUNAM PumasLiga MX · Mexico | 1–2 | Liga MX · Mexico |
| 2016-04-17 | DortmundvHamburgBundesliga · Germany | 3–0 | Bundesliga · Germany |
| 2016-04-17 | Velez SarsfieldvIndependienteLiga Profesional · Argentina | 0–2 | Liga Profesional · Argentina |
| 2016-04-17 | UfavFK Anzi MakhackalaPremier League · Russia | 2–0 | Premier League · Russia |
| 2016-04-17 | VallecanovVillarrealLa Liga · Spain | 2–1 | La Liga · Spain |
| 2016-04-17 | RennesvGuingampLigue 1 · France | 0–3 | Ligue 1 · France |
| 2016-04-17 | SampdoriavMilanSerie A · Italy | 0–1 | Serie A · Italy |