| 2016-04-19 | Nott'm ForestvBlackburnChampionship · England | 1–1 | Championship · England |
| 2016-04-19 | Dag and RedvAFC WimbledonLeague Two · England | 0–2 | League Two · England |
| 2016-04-19 | ExetervMansfieldLeague Two · England | 2–3 | League Two · England |
| 2016-04-19 | Virtus LancianovNovaraSerie B · Italy | 2–1 | Serie B · Italy |
| 2016-04-19 | CarlislevLutonLeague Two · England | 1–2 | League Two · England |
| 2016-04-19 | SouthendvOldhamLeague One · England | 0–1 | League One · England |
| 2016-04-19 | CambridgevMorecambeLeague Two · England | 7–0 | League Two · England |
| 2016-04-19 | PSV EindhovenvVitesseEredivisie · Netherlands | 2–0 | Eredivisie · Netherlands |
| 2016-04-19 | HalifaxvEastleighNational League · England | 0–0 | National League · England |
| 2016-04-19 | AvellinovTrapaniSerie B · Italy | 1–3 | Serie B · Italy |
| 2016-04-19 | ReadingvHullChampionship · England | 1–2 | Championship · England |
| 2016-04-19 | CrewevColchesterLeague One · England | 1–1 | League One · England |
| 2016-04-19 | TernanavPro VercelliSerie B · Italy | 2–2 | Serie B · Italy |
| 2016-04-19 | AscolivBariSerie B · Italy | 0–1 | Serie B · Italy |
| 2016-04-19 | CracoviavZaglebieEkstraklasa · Poland | 1–0 | Ekstraklasa · Poland |
| 2016-04-19 | YorkvPortsmouthLeague Two · England | 3–1 | League Two · England |
| 2016-04-19 | Newport CountyvOxfordLeague Two · England | 1–1 | League Two · England |
| 2016-04-19 | WycombevYeovilLeague Two · England | 0–0 | League Two · England |
| 2016-04-19 | BrentfordvCardiffChampionship · England | 2–1 | Championship · England |
| 2016-04-19 | NapolivBolognaSerie A · Italy | 6–0 | Serie A · Italy |
| 2016-04-19 | MillwallvFleetwood TownLeague One · England | 1–0 | League One · England |
| 2016-04-19 | BirminghamvPrestonChampionship · England | 2–2 | Championship · England |
| 2016-04-19 | EspanolvCeltaLa Liga · Spain | 1–1 | La Liga · Spain |
| 2016-04-19 | ScunthorpevBuryLeague One · England | 2–1 | League One · England |
| 2016-04-19 | BoltonvCharltonChampionship · England | 0–0 | Championship · England |
| 2016-04-19 | Lech PoznanvPiast GliwiceEkstraklasa · Poland | 2–2 | Ekstraklasa · Poland |
| 2016-04-19 | ModenavPerugiaSerie B · Italy | 3–0 | Serie B · Italy |
| 2016-04-19 | Bristol CityvDerbyChampionship · England | 2–3 | Championship · England |
| 2016-04-19 | IpswichvFulhamChampionship · England | 1–1 | Championship · England |
| 2016-04-19 | BrightonvQPRChampionship · England | 4–0 | Championship · England |
| 2016-04-19 | BarnsleyvPeterboroLeague One · England | 1–0 | League One · England |
| 2016-04-19 | Sheffield WedsvMilton Keynes DonsChampionship · England | 0–0 | Championship · England |
| 2016-04-19 | BetisvLas PalmasLa Liga · Spain | 1–0 | La Liga · Spain |
| 2016-04-19 | RuchvLegiaEkstraklasa · Poland | 0–0 | Ekstraklasa · Poland |
| 2016-04-19 | HartlepoolvAccringtonLeague Two · England | 1–2 | League Two · England |
| 2016-04-19 | LeedsvWolvesChampionship · England | 2–1 | Championship · England |
| 2016-04-19 | GroningenvRodaEredivisie · Netherlands | 1–0 | Eredivisie · Netherlands |
| 2016-04-19 | StevenagevBristol RvsLeague Two · England | 0–0 | League Two · England |
| 2016-04-19 | CoventryvBradfordLeague One · England | 1–0 | League One · England |
| 2016-04-19 | SpeziavPescaraSerie B · Italy | 0–1 | Serie B · Italy |
| 2016-04-19 | BurnleyvMiddlesbroughChampionship · England | 1–1 | Championship · England |
| 2016-04-19 | LivornovLatinaSerie B · Italy | 1–0 | Serie B · Italy |
| 2016-04-19 | ZurichvGrasshoppersSuper League · Switzerland | 1–1 | Super League · Switzerland |
| 2016-04-19 | WokingvGrimsbyNational League · England | 1–3 | National League · England |
| 2016-04-19 | ComovCagliariSerie B · Italy | 1–1 | Serie B · Italy |
| 2016-04-19 | DjurgardenvHammarbyAllsvenskan · Sweden | 1–3 | Allsvenskan · Sweden |
| 2016-04-19 | ChesterfieldvDoncasterLeague One · England | 1–1 | League One · England |
| 2016-04-19 | BresciavVirtus EntellaSerie B · Italy | 2–0 | Serie B · Italy |
| 2016-04-19 | Leyton OrientvPlymouthLeague Two · England | 1–3 | League Two · England |
| 2016-04-19 | Lechia GdanskvPogon SzczecinEkstraklasa · Poland | 2–0 | Ekstraklasa · Poland |