| 2016-04-23 | MacclesfieldvCheltenhamNational League · England | 0–1 | National League · England |
| 2016-04-23 | Airdrie UtdvDunfermlineLeague One · Scotland | 3–0 | League One · Scotland |
| 2016-04-23 | Man CityvStokePremier League · England | 4–0 | Premier League · England |
| 2016-04-23 | Schalke 04vLeverkusenBundesliga · Germany | 2–3 | Bundesliga · Germany |
| 2016-04-23 | CowdenbeathvStenhousemuirLeague One · Scotland | 1–3 | League One · Scotland |
| 2016-04-23 | BuryvMillwallLeague One · England | 1–3 | League One · England |
| 2016-04-23 | Queen of SthvLivingstonChampionship · Scotland | 3–1 | Championship · Scotland |
| 2016-04-23 | QPRvReadingChampionship · England | 1–1 | Championship · England |
| 2016-04-23 | Sp LisbonvUniao MadeiraPrimeira Liga · Portugal | 2–0 | Primeira Liga · Portugal |
| 2016-04-23 | OxfordvHartlepoolLeague Two · England | 2–0 | League Two · England |
| 2016-04-23 | AltrinchamvWelling UnitedNational League · England | 5–0 | National League · England |
| 2016-04-23 | HuddersfieldvBirminghamChampionship · England | 1–1 | Championship · England |
| 2016-04-23 | ColchestervBurtonLeague One · England | 0–3 | League One · England |
| 2016-04-23 | Rubin KazanvAkhmat GroznyPremier League · Russia | 0–1 | Premier League · Russia |
| 2016-04-23 | BarcelonavSp GijonLa Liga · Spain | 6–0 | La Liga · Spain |
| 2016-04-23 | HammarbyvJonkopingsAllsvenskan · Sweden | 1–1 | Allsvenskan · Sweden |
| 2016-04-23 | Guangzhou R&FvJiangsu SuningSuper League · China | 1–1 | Super League · China |
| 2016-04-23 | KidderminstervDover AthleticNational League · England | 1–1 | National League · England |
| 2016-04-22 | Evian Thonon GaillardvLe HavreLigue 2 · France | 1–1 | Ligue 2 · France |
| 2016-04-22 | MidtjyllandvOdenseSuperliga · Denmark | 2–0 | Superliga · Denmark |
| 2016-04-22 | FalkenbergsvNorrkopingAllsvenskan · Sweden | 2–1 | Allsvenskan · Sweden |
| 2016-04-22 | Fortuna DusseldorfvSt Pauli2. Bundesliga · Germany | 1–1 | 2. Bundesliga · Germany |
| 2016-04-22 | Las PalmasvEspanolLa Liga · Spain | 4–0 | La Liga · Spain |
| 2016-04-22 | HamburgvWerder BremenBundesliga · Germany | 2–1 | Bundesliga · Germany |
| 2016-04-22 | Shamrock RoversvDundalkPremier Division · Ireland | 0–2 | Premier Division · Ireland |
| 2016-04-22 | AjacciovValenciennesLigue 2 · France | 1–1 | Ligue 2 · France |
| 2016-04-22 | PrestonvBurnleyChampionship · England | 0–1 | Championship · England |
| 2016-04-22 | Cork CityvFinn HarpsPremier Division · Ireland | 3–1 | Premier Division · Ireland |
| 2016-04-22 | NiortvBourg PeronnasLigue 2 · France | 0–0 | Ligue 2 · France |
| 2016-04-22 | PetrolulvFC BotosaniSuperliga · Romania | 0–4 | Superliga · Romania |
| 2016-04-22 | St JohnstonevAberdeenPremiership · Scotland | 3–0 | Premiership · Scotland |
| 2016-04-22 | BochumvKarlsruhe2. Bundesliga · Germany | 1–1 | 2. Bundesliga · Germany |
| 2016-04-22 | NimesvLensLigue 2 · France | 4–2 | Ligue 2 · France |
| 2016-04-22 | BoavistavBelenensesPrimeira Liga · Portugal | 1–0 | Primeira Liga · Portugal |
| 2016-04-22 | Paris FCvCreteilLigue 2 · France | 2–2 | Ligue 2 · France |
| 2016-04-22 | KayserisporvBursasporSüper Lig · Turkey | 2–1 | Süper Lig · Turkey |
| 2016-04-22 | LegiavCracoviaEkstraklasa · Poland | 4–0 | Ekstraklasa · Poland |
| 2016-04-22 | ClermontvToursLigue 2 · France | 0–1 | Ligue 2 · France |
| 2016-04-22 | Derry CityvBohemiansPremier Division · Ireland | 1–0 | Premier Division · Ireland |
| 2016-04-22 | Hangzhou GreentownvChongqing Liangjiang AthleticSuper League · China | 1–1 | Super League · China |
| 2016-04-22 | MetzvRed StarLigue 2 · France | 2–0 | Ligue 2 · France |
| 2016-04-22 | ZaglebievRuchEkstraklasa · Poland | 4–1 | Ekstraklasa · Poland |
| 2016-04-22 | NicevReimsLigue 1 · France | 2–0 | Ligue 1 · France |
| 2016-04-22 | Atl. RafaelavPatronatoLiga Profesional · Argentina | 3–1 | Liga Profesional · Argentina |
| 2016-04-22 | BrestvLavalLigue 2 · France | 0–0 | Ligue 2 · France |
| 2016-04-22 | FreiburgvDuisburg2. Bundesliga · Germany | 3–0 | 2. Bundesliga · Germany |
| 2016-04-22 | WexfordvGalwayPremier Division · Ireland | 0–2 | Premier Division · Ireland |
| 2016-04-21 | CambuurvWillem IIEredivisie · Netherlands | 1–1 | Eredivisie · Netherlands |
| 2016-04-21 | MoldevValerengaEliteserien · Norway | 4–0 | Eliteserien · Norway |
| 2016-04-21 | StartvSarpsborg 08Eliteserien · Norway | 1–4 | Eliteserien · Norway |