| 2006-01-02 | Rushden & DvBristol RvsLeague Two · England | 2–3 | League Two · England |
| 2006-01-02 | St JohnstonevDundeeChampionship · Scotland | 0–0 | Championship · Scotland |
| 2006-01-02 | GretnavAyrLeague One · Scotland | 3–0 | League One · Scotland |
| 2006-01-02 | NewcastlevMiddlesbroughPremier League · England | 2–2 | Premier League · England |
| 2006-01-02 | BoltonvLiverpoolPremier League · England | 2–2 | Premier League · England |
| 2006-01-02 | ColchestervNott'm ForestLeague One · England | 3–1 | League One · England |
| 2006-01-02 | FulhamvSunderlandPremier League · England | 2–1 | Premier League · England |
| 2006-01-02 | KilmarnockvHibernianPremiership · Scotland | 2–2 | Premiership · Scotland |
| 2006-01-02 | ScarboroughvYorkNational League · England | 2–2 | National League · England |
| 2006-01-02 | BradfordvBrentfordLeague One · England | 3–3 | League One · England |
| 2006-01-02 | NorwichvPrestonChampionship · England | 0–3 | Championship · England |
| 2006-01-02 | MorecambevSouthportNational League · England | 0–0 | National League · England |
| 2006-01-02 | MontrosevArbroathLeague Two · Scotland | 0–1 | League Two · Scotland |
| 2006-01-02 | MansfieldvLincolnLeague Two · England | 0–0 | League Two · England |
| 2006-01-02 | StranraervQueen of SthChampionship · Scotland | 1–0 | Championship · Scotland |
| 2006-01-02 | BlackburnvPortsmouthPremier League · England | 2–1 | Premier League · England |
| 2006-01-02 | PlymouthvLeedsChampionship · England | 0–3 | Championship · England |
| 2006-01-02 | PeterborovBuryLeague Two · England | 4–1 | League Two · England |
| 2006-01-02 | BirminghamvWiganPremier League · England | 2–0 | Premier League · England |
| 2006-01-02 | HamiltonvAirdrie UtdChampionship · Scotland | 1–0 | Championship · Scotland |
| 2006-01-02 | StenhousemuirvEast StirlingLeague Two · Scotland | 5–0 | League Two · Scotland |
| 2006-01-02 | ForfarvPeterheadLeague One · Scotland | 0–1 | League One · Scotland |
| 2006-01-02 | HerefordvForest GreenNational League · England | 1–1 | National League · England |
| 2006-01-02 | Canvey IslandvGraysNational League · England | 2–1 | National League · England |
| 2006-01-02 | DoncastervYeovilLeague One · England | 0–1 | League One · England |
| 2006-01-02 | CoventryvWolvesChampionship · England | 2–0 | Championship · England |
| 2006-01-02 | SwanseavPort ValeLeague One · England | 0–0 | League One · England |
| 2006-01-02 | West BromvAston VillaPremier League · England | 1–2 | Premier League · England |
| 2006-01-02 | St MirrenvClydeChampionship · Scotland | 2–1 | Championship · Scotland |
| 2006-01-02 | WycombevMacclesfieldLeague Two · England | 4–5 | League Two · England |
| 2006-01-02 | AltrinchamvKidderminsterNational League · England | 3–0 | National League · England |
| 2006-01-02 | Dag and RedvGravesendNational League · England | 1–2 | National League · England |
| 2006-01-02 | AccringtonvHalifaxNational League · England | 1–1 | National League · England |
| 2006-01-02 | Bristol CityvWalsallLeague One · England | 3–0 | League One · England |
| 2006-01-02 | Milton Keynes DonsvOldhamLeague One · England | 0–1 | League One · England |
| 2006-01-02 | StockportvCheltenhamLeague Two · England | 2–2 | League Two · England |
| 2006-01-02 | Sheffield WedsvCreweChampionship · England | 3–0 | Championship · England |
| 2006-01-02 | ChesterfieldvBarnsleyLeague One · England | 0–0 | League One · England |
| 2006-01-02 | StokevIpswichChampionship · England | 2–2 | Championship · England |
| 2006-01-02 | East FifevCowdenbeathLeague Two · Scotland | 2–1 | League Two · Scotland |
| 2006-01-02 | DumbartonvMortonLeague One · Scotland | 0–2 | League One · Scotland |
| 2006-01-02 | GrimsbyvCarlisleLeague Two · England | 1–2 | League Two · England |
| 2006-01-02 | RochdalevNorthamptonLeague Two · England | 1–1 | League Two · England |
| 2006-01-02 | Crawley TownvWokingNational League · England | 2–2 | National League · England |
| 2006-01-02 | Ross CountyvBrechinChampionship · Scotland | 2–0 | Championship · Scotland |
| 2006-01-02 | BlackpoolvSouthendLeague One · England | 1–2 | League One · England |
| 2006-01-02 | BostonvLeyton OrientLeague Two · England | 1–2 | League Two · England |
| 2006-01-02 | ReadingvCardiffChampionship · England | 5–1 | Championship · England |
| 2006-01-02 | HuddersfieldvGillinghamLeague One · England | 0–0 | League One · England |
| 2006-01-02 | StevenagevCambridgeNational League · England | 3–1 | National League · England |