| 2016-04-23 | Akhisar BelediyesporvBesiktasSüper Lig · Turkey | 3–3 | Süper Lig · Turkey |
| 2016-04-23 | San LorenzovHuracanLiga Profesional · Argentina | 1–0 | Liga Profesional · Argentina |
| 2016-04-23 | DC UnitedvNew England RevolutionMLS · United States | 3–0 | MLS · United States |
| 2016-04-23 | Raith RvsvFalkirkChampionship · Scotland | 2–2 | Championship · Scotland |
| 2016-04-23 | PodbeskidzievSlask WroclawEkstraklasa · Poland | 1–2 | Ekstraklasa · Poland |
| 2016-04-23 | DoncastervCoventryLeague One · England | 2–0 | League One · England |
| 2016-04-23 | Club AmericavTolucaLiga MX · Mexico | 0–1 | Liga MX · Mexico |
| 2016-04-23 | Pogon SzczecinvLech PoznanEkstraklasa · Poland | 1–0 | Ekstraklasa · Poland |
| 2016-04-23 | Albion RvsvForfarLeague One · Scotland | 3–2 | League One · Scotland |
| 2016-04-23 | Union de Santa FevColon Santa FELiga Profesional · Argentina | 1–0 | Liga Profesional · Argentina |
| 2016-04-23 | SionvLuganoSuper League · Switzerland | 3–1 | Super League · Switzerland |
| 2016-04-23 | Arsenal SarandivDefensa y JusticiaLiga Profesional · Argentina | 0–0 | Liga Profesional · Argentina |
| 2016-04-23 | WrexhamvBraintree TownNational League · England | 2–3 | National League · England |
| 2016-04-23 | LeganesvPonferradinaLa Liga 2 · Spain | 3–0 | La Liga 2 · Spain |
| 2016-04-23 | BuyuksehyrvSivassporSüper Lig · Turkey | 2–2 | Süper Lig · Turkey |
| 2016-04-23 | HullvLeedsChampionship · England | 2–2 | Championship · England |
| 2016-04-23 | AlbacetevGironaLa Liga 2 · Spain | 0–3 | La Liga 2 · Spain |
| 2016-04-23 | UNAM PumasvClub TijuanaLiga MX · Mexico | 3–1 | Liga MX · Mexico |
| 2016-04-23 | StirlingvAnnan AthleticLeague Two · Scotland | 2–1 | League Two · Scotland |
| 2016-04-23 | TernanavAscoliSerie B · Italy | 1–3 | Serie B · Italy |
| 2016-04-23 | VicenzavSpeziaSerie B · Italy | 0–3 | Serie B · Italy |
| 2016-04-23 | PortsmouthvWycombeLeague Two · England | 2–1 | League Two · England |
| 2016-04-23 | IngolstadtvHannoverBundesliga · Germany | 2–2 | Bundesliga · Germany |
| 2016-04-23 | Spartak MoscowvM. SaranskPremier League · Russia | 2–2 | Premier League · Russia |
| 2016-04-23 | Godoy CruzvSan Martin S.J.Liga Profesional · Argentina | 1–0 | Liga Profesional · Argentina |
| 2016-04-23 | IntervUdineseSerie A · Italy | 3–1 | Serie A · Italy |
| 2016-04-23 | StromsgodsetvBodo/GlimtEliteserien · Norway | 2–0 | Eliteserien · Norway |
| 2016-04-23 | RangersvAlloaChampionship · Scotland | 1–1 | Championship · Scotland |
| 2016-04-23 | Fleetwood TownvBlackpoolLeague One · England | 0–0 | League One · England |
| 2016-04-23 | BrechinvStranraerLeague One · Scotland | 1–0 | League One · Scotland |
| 2016-04-23 | ArbroathvMontroseLeague Two · Scotland | 0–0 | League Two · Scotland |
| 2016-04-23 | SwindonvChesterfieldLeague One · England | 1–0 | League One · England |
| 2016-04-23 | BerwickvEast FifeLeague Two · Scotland | 2–0 | League Two · Scotland |
| 2016-04-23 | LanusvBanfieldLiga Profesional · Argentina | 2–0 | Liga Profesional · Argentina |
| 2016-04-23 | PlymouthvDag and RedLeague Two · England | 2–3 | League Two · England |
| 2016-04-23 | HeidenheimvPaderborn2. Bundesliga · Germany | 1–1 | 2. Bundesliga · Germany |
| 2016-04-23 | GrodigvWolfsberger ACBundesliga · Austria | 0–1 | Bundesliga · Austria |
| 2016-04-23 | Sligo RoversvLongfordPremier Division · Ireland | 3–0 | Premier Division · Ireland |
| 2016-04-23 | WiganvSouthendLeague One · England | 4–1 | League One · England |
| 2016-04-23 | BlackburnvBristol CityChampionship · England | 2–2 | Championship · England |
| 2016-04-23 | OldhamvCreweLeague One · England | 1–0 | League One · England |
| 2016-04-23 | BrayvSt. PatricksPremier Division · Ireland | 1–0 | Premier Division · Ireland |
| 2016-04-23 | Philadelphia UnionvNew York CityMLS · United States | 2–0 | MLS · United States |
| 2016-04-23 | Queens ParkvClydeLeague Two · Scotland | 2–1 | League Two · Scotland |
| 2016-04-23 | Forest GreenvHalifaxNational League · England | 0–1 | National League · England |
| 2016-04-23 | LiverpoolvNewcastlePremier League · England | 2–2 | Premier League · England |
| 2016-04-23 | BrannvSogndalEliteserien · Norway | 2–0 | Eliteserien · Norway |
| 2016-04-23 | PeterborovScunthorpeLeague One · England | 0–2 | League One · England |
| 2016-04-23 | AlavesvElcheLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2016-04-23 | OviedovHuescaLa Liga 2 · Spain | 0–1 | La Liga 2 · Spain |