| 2016-04-24 | San Jose EarthquakesvSporting Kansas CityMLS · United States | 1–0 | MLS · United States |
| 2016-04-24 | M'gladbachvHoffenheimBundesliga · Germany | 3–1 | Bundesliga · Germany |
| 2016-04-24 | AtlasvClub LeonLiga MX · Mexico | 1–1 | Liga MX · Mexico |
| 2016-04-24 | Gimnasia L.P.vEstudiantes L.P.Liga Profesional · Argentina | 0–0 | Liga Profesional · Argentina |
| 2016-04-24 | AtalantavChievoSerie A · Italy | 1–0 | Serie A · Italy |
| 2016-04-24 | Changchun YataivShanghai SIPGSuper League · China | 1–3 | Super League · China |
| 2016-04-24 | SJKvIlvesVeikkausliiga · Finland | 0–2 | Veikkausliiga · Finland |
| 2016-04-24 | LugovMallorcaLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2016-04-24 | SevillavBetisLa Liga · Spain | 2–0 | La Liga · Spain |
| 2016-04-24 | RovaniemivPK-35 VantaaVeikkausliiga · Finland | 1–0 | Veikkausliiga · Finland |
| 2016-04-24 | MontpelliervTroyesLigue 1 · France | 4–1 | Ligue 1 · France |
| 2016-04-24 | Ein FrankfurtvMainzBundesliga · Germany | 2–1 | Bundesliga · Germany |
| 2016-04-24 | ShijiazhuangvShandong LunengSuper League · China | 2–1 | Super League · China |
| 2016-04-24 | Yokohama F. MarinosvSanfrecce HiroshimaJ1 League · Japan | 1–2 | J1 League · Japan |
| 2016-04-24 | Sarpsborg 08vMoldeEliteserien · Norway | 4–0 | Eliteserien · Norway |
| 2016-04-24 | JagielloniavGornik Z.Ekstraklasa · Poland | 0–0 | Ekstraklasa · Poland |
| 2016-04-24 | CSKA MoscowvDynamo MoscowPremier League · Russia | 1–0 | Premier League · Russia |
| 2016-04-24 | Newells Old BoysvRosario CentralLiga Profesional · Argentina | 0–0 | Liga Profesional · Argentina |
| 2016-04-24 | OrebrovGoteborgAllsvenskan · Sweden | 3–2 | Allsvenskan · Sweden |
| 2016-04-24 | TrabzonsporvFenerbahceSüper Lig · Turkey | 0–4 | Süper Lig · Turkey |
| 2016-04-24 | Ajaccio GFCOvBastiaLigue 1 · France | 3–2 | Ligue 1 · France |
| 2016-04-24 | CFR ClujvPoli IasiSuperliga · Romania | 0–0 | Superliga · Romania |
| 2016-04-24 | Columbus CrewvHouston DynamoMLS · United States | 1–0 | MLS · United States |
| 2016-04-24 | Los Angeles GalaxyvReal Salt LakeMLS · United States | 5–2 | MLS · United States |
| 2016-04-24 | BielefeldvGreuther Furth2. Bundesliga · Germany | 4–2 | 2. Bundesliga · Germany |
| 2016-04-24 | Nagoya GrampusvAlbirex NiigataJ1 League · Japan | 2–1 | J1 League · Japan |
| 2016-04-24 | TorinovSassuoloSerie A · Italy | 1–3 | Serie A · Italy |
| 2016-04-24 | ZaragozavAlcorconLa Liga 2 · Spain | 3–1 | La Liga 2 · Spain |
| 2016-04-24 | PueblavChiapasLiga MX · Mexico | 2–1 | Liga MX · Mexico |
| 2016-04-23 | MotherwellvHeartsPremiership · Scotland | 1–0 | Premiership · Scotland |
| 2016-04-23 | YanbianvHenan Songshan LongmenSuper League · China | 1–2 | Super League · China |
| 2016-04-23 | Beijing GuoanvLiaoningSuper League · China | 0–0 | Super League · China |
| 2016-04-23 | AldershotvSouthportNational League · England | 1–2 | National League · England |
| 2016-04-23 | BournemouthvChelseaPremier League · England | 1–4 | Premier League · England |
| 2016-04-23 | TrapanivCesenaSerie B · Italy | 2–1 | Serie B · Italy |
| 2016-04-23 | WolvesvRotherhamChampionship · England | 0–0 | Championship · England |
| 2016-04-23 | ToulousevLyonLigue 1 · France | 2–3 | Ligue 1 · France |
| 2016-04-23 | Crawley TownvCarlisleLeague Two · England | 0–1 | League Two · England |
| 2016-04-23 | Bristol RvsvExeterLeague Two · England | 3–1 | League Two · England |
| 2016-04-23 | Boreham WoodvGuiseleyNational League · England | 1–0 | National League · England |
| 2016-04-23 | MorecambevStevenageLeague Two · England | 1–4 | League Two · England |
| 2016-04-23 | RiedvAdmiraBundesliga · Austria | 1–0 | Bundesliga · Austria |
| 2016-04-23 | AuxerrevDijonLigue 2 · France | 2–0 | Ligue 2 · France |
| 2016-04-23 | FulhamvNott'm ForestChampionship · England | 1–3 | Championship · England |
| 2016-04-23 | LlagosteravGimnasticLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2016-04-23 | AFC WimbledonvLeyton OrientLeague Two · England | 1–0 | League Two · England |
| 2016-04-23 | Milton Keynes DonsvBrentfordChampionship · England | 1–4 | Championship · England |
| 2016-04-23 | MiddlesbroughvIpswichChampionship · England | 0–0 | Championship · England |
| 2016-04-23 | TorquayvBarrowNational League · England | 2–2 | National League · England |
| 2016-04-23 | BarivModenaSerie B · Italy | 1–1 | Serie B · Italy |