| 2022-04-26 | AvaivGoiasSerie A · Brazil | 3–2 | Serie A · Brazil |
| 2022-04-26 | SwanseavBournemouthChampionship · England | 3–3 | Championship · England |
| 2022-04-26 | AldosivivHuracanCopa De La Liga Profesional · Argentina | 0–2 | Copa De La Liga Profesional · Argentina |
| 2022-04-26 | Fleetwood TownvSheffield WedsLeague One · England | 2–3 | League One · England |
| 2022-04-26 | PortsmouthvWiganLeague One · England | 3–2 | League One · England |
| 2022-04-26 | ExetervBarrowLeague Two · England | 2–1 | League Two · England |
| 2022-04-26 | Dover AthleticvNotts CountyNational League · England | 0–3 | National League · England |
| 2022-04-26 | FulhamvNott'm ForestChampionship · England | 0–1 | Championship · England |
| 2022-04-26 | BromleyvAldershotNational League · England | 1–1 | National League · England |
| 2022-04-26 | SwindonvForest GreenLeague Two · England | 2–1 | League Two · England |
| 2022-04-26 | SunderlandvRotherhamLeague One · England | 1–1 | League One · England |
| 2022-04-26 | SouthendvBoreham WoodNational League · England | 1–0 | National League · England |
| 2022-04-25 | WislavWisla PlockEkstraklasa · Poland | 3–4 | Ekstraklasa · Poland |
| 2022-04-25 | LeccevPisaSerie B · Italy | 2–0 | Serie B · Italy |
| 2022-04-25 | FrosinonevMonzaSerie B · Italy | 4–1 | Serie B · Italy |
| 2022-04-25 | ComovVicenzaSerie B · Italy | 0–2 | Serie B · Italy |
| 2022-04-25 | Malmo FFvGoteborgAllsvenskan · Sweden | 1–0 | Allsvenskan · Sweden |
| 2022-04-25 | HonkavSJKVeikkausliiga · Finland | 5–1 | Veikkausliiga · Finland |
| 2022-04-25 | SassuolovJuventusSerie A · Italy | 1–2 | Serie A · Italy |
| 2022-04-25 | BoavistavSp LisbonPrimeira Liga · Portugal | 0–3 | Primeira Liga · Portugal |
| 2022-04-25 | CosenzavPordenoneSerie B · Italy | 3–1 | Serie B · Italy |
| 2022-04-25 | PrestonvBlackburnChampionship · England | 1–4 | Championship · England |
| 2022-04-25 | BeneventovTernanaSerie B · Italy | 1–2 | Serie B · Italy |
| 2022-04-25 | AlmeriavSp GijonLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2022-04-25 | TigrevArsenal SarandiCopa De La Liga Profesional · Argentina | 0–0 | Copa De La Liga Profesional · Argentina |
| 2022-04-25 | Crystal PalacevLeedsPremier League · England | 0–0 | Premier League · England |
| 2022-04-25 | BresciavSpalSerie B · Italy | 1–1 | Serie B · Italy |
| 2022-04-25 | BrondbyvMidtjyllandSuperliga · Denmark | 1–3 | Superliga · Denmark |
| 2022-04-25 | Farul ConstantavFCSBSuperliga · Romania | 0–4 | Superliga · Romania |
| 2022-04-25 | BesiktasvKasimpasaSüper Lig · Turkey | 0–3 | Süper Lig · Turkey |
| 2022-04-25 | Sp BragavPortoPrimeira Liga · Portugal | 1–0 | Primeira Liga · Portugal |
| 2022-04-25 | AlessandriavRegginaSerie B · Italy | 0–0 | Serie B · Italy |
| 2022-04-25 | Santos LagunavClub LeonLiga MX · Mexico | 1–1 | Liga MX · Mexico |
| 2022-04-25 | SivassporvAlanyasporSüper Lig · Turkey | 1–0 | Süper Lig · Turkey |
| 2022-04-25 | Godoy CruzvLanusCopa De La Liga Profesional · Argentina | 1–1 | Copa De La Liga Profesional · Argentina |
| 2022-04-25 | Club TijuanavQueretaroLiga MX · Mexico | 2–2 | Liga MX · Mexico |
| 2022-04-25 | ToulousevNiortLigue 2 · France | 2–0 | Ligue 2 · France |
| 2022-04-25 | FC ArgesvUniv. CraiovaSuperliga · Romania | 0–4 | Superliga · Romania |
| 2022-04-25 | CrotonevCremoneseSerie B · Italy | 3–1 | Serie B · Italy |
| 2022-04-25 | VarnamovDegerforsAllsvenskan · Sweden | 2–0 | Allsvenskan · Sweden |
| 2022-04-25 | FC BotosanivU Craiova 1948Superliga · Romania | 2–1 | Superliga · Romania |
| 2022-04-25 | ElfsborgvSundsvallAllsvenskan · Sweden | 3–1 | Allsvenskan · Sweden |
| 2022-04-25 | Defensa y JusticiavPlatenseCopa De La Liga Profesional · Argentina | 1–1 | Copa De La Liga Profesional · Argentina |
| 2022-04-25 | SiriusvHammarbyAllsvenskan · Sweden | 0–3 | Allsvenskan · Sweden |
| 2022-04-25 | PerugiavParmaSerie B · Italy | 2–1 | Serie B · Italy |
| 2022-04-25 | KrasnodarvZenitPremier League · Russia | 1–3 | Premier League · Russia |
| 2022-04-25 | AscolivCittadellaSerie B · Italy | 0–0 | Serie B · Italy |
| 2022-04-24 | Orlando CityvNew York Red BullsMLS · United States | 0–3 | MLS · United States |
| 2022-04-24 | River PlatevAtl. TucumanCopa De La Liga Profesional · Argentina | 1–1 | Copa De La Liga Profesional · Argentina |
| 2022-04-24 | LugovLeganesLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |