| 2021-05-12 | Ath MadridvSociedadLa Liga · Spain | 2–1 | La Liga · Spain |
| 2021-05-12 | CagliarivFiorentinaSerie A · Italy | 0–0 | Serie A · Italy |
| 2021-05-12 | Ross CountyvHamiltonPremiership · Scotland | 2–1 | Premiership · Scotland |
| 2021-05-12 | LaziovParmaSerie A · Italy | 1–0 | Serie A · Italy |
| 2021-05-12 | CelticvSt JohnstonePremiership · Scotland | 4–0 | Premiership · Scotland |
| 2021-05-11 | Dalian ProvTianjin Jinmen TigerSuper League · China | 1–0 | Super League · China |
| 2021-05-11 | IlvesvHJKVeikkausliiga · Finland | 0–3 | Veikkausliiga · Finland |
| 2021-05-11 | LahtivKuPSVeikkausliiga · Finland | 2–4 | Veikkausliiga · Finland |
| 2021-05-11 | Santa ClaravRio AvePrimeira Liga · Portugal | 1–0 | Primeira Liga · Portugal |
| 2021-05-11 | BaselvLuganoSuper League · Switzerland | 2–0 | Super League · Switzerland |
| 2021-05-11 | GenclerbirligivGoztepSüper Lig · Turkey | 5–3 | Süper Lig · Turkey |
| 2021-05-11 | DenizlisporvGalatasaraySüper Lig · Turkey | 1–4 | Süper Lig · Turkey |
| 2021-05-11 | SouthamptonvCrystal PalacePremier League · England | 3–1 | Premier League · England |
| 2021-05-11 | BuyuksehyrvKayserisporSüper Lig · Turkey | 0–0 | Süper Lig · Turkey |
| 2021-05-11 | KasimpasavAnkaragucuSüper Lig · Turkey | 3–1 | Süper Lig · Turkey |
| 2021-05-11 | SuttonvWokingNational League · England | 3–2 | National League · England |
| 2021-05-11 | NacionalvBenficaPrimeira Liga · Portugal | 1–3 | Primeira Liga · Portugal |
| 2021-05-11 | TondelavBelenensesPrimeira Liga · Portugal | 1–3 | Primeira Liga · Portugal |
| 2021-05-11 | BesiktasvKaragumrukSüper Lig · Turkey | 1–2 | Süper Lig · Turkey |
| 2021-05-11 | FenerbahcevSivassporSüper Lig · Turkey | 1–2 | Süper Lig · Turkey |
| 2021-05-11 | ElchevAlavesLa Liga · Spain | 0–2 | La Liga · Spain |
| 2021-05-11 | Austria ViennavHartbergBundesliga · Austria | 3–1 | Bundesliga · Austria |
| 2021-05-11 | OsasunavCadizLa Liga · Spain | 3–2 | La Liga · Spain |
| 2021-05-11 | StockportvDag and RedNational League · England | 1–1 | National League · England |
| 2021-05-11 | WealdstonevBromleyNational League · England | 0–1 | National League · England |
| 2021-05-11 | AldershotvYeovilNational League · England | 2–0 | National League · England |
| 2021-05-11 | AlanyasporvErzurum BBSüper Lig · Turkey | 2–3 | Süper Lig · Turkey |
| 2021-05-11 | VaduzvYoung BoysSuper League · Switzerland | 0–2 | Super League · Switzerland |
| 2021-05-11 | KonyasporvTrabzonsporSüper Lig · Turkey | 1–1 | Süper Lig · Turkey |
| 2021-05-11 | Shanghai PortvChangchun YataiSuper League · China | 0–0 | Super League · China |
| 2021-05-11 | NapolivUdineseSerie A · Italy | 5–1 | Serie A · Italy |
| 2021-05-11 | Sp LisbonvBoavistaPrimeira Liga · Portugal | 1–0 | Primeira Liga · Portugal |
| 2021-05-11 | ChesterfieldvKings LynnNational League · England | 4–1 | National League · England |
| 2021-05-11 | LevantevBarcelonaLa Liga · Spain | 3–3 | La Liga · Spain |
| 2021-05-11 | Man UnitedvLeicesterPremier League · England | 1–2 | Premier League · England |
| 2021-05-11 | MaidenheadvNotts CountyNational League · England | 0–4 | National League · England |
| 2021-05-11 | Yeni MalatyasporvHataysporSüper Lig · Turkey | 1–1 | Süper Lig · Turkey |
| 2021-05-11 | SolihullvWeymouthNational League · England | 2–1 | National League · England |
| 2021-05-11 | GaziantepvRizesporSüper Lig · Turkey | 4–5 | Süper Lig · Turkey |
| 2021-05-11 | St. PoltenvAltachBundesliga · Austria | 3–3 | Bundesliga · Austria |
| 2021-05-11 | RiedvAdmiraBundesliga · Austria | 0–0 | Bundesliga · Austria |
| 2021-05-10 | NordsjaellandvFC CopenhagenSuperliga · Denmark | 2–2 | Superliga · Denmark |
| 2021-05-10 | Sp GijonvLugoLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2021-05-10 | PortovFarensePrimeira Liga · Portugal | 5–1 | Primeira Liga · Portugal |
| 2021-05-10 | VicenzavReggianaSerie B · Italy | 2–1 | Serie B · Italy |
| 2021-05-10 | EmpolivLecceSerie B · Italy | 2–1 | Serie B · Italy |
| 2021-05-10 | PescaravSalernitanaSerie B · Italy | 0–3 | Serie B · Italy |
| 2021-05-10 | Holstein KielvHannover2. Bundesliga · Germany | 1–0 | 2. Bundesliga · Germany |
| 2021-05-10 | Club LeonvTolucaLiga MX · Mexico | 2–2 | Liga MX · Mexico |
| 2021-05-10 | Wuhan FCvBeijing GuoanSuper League · China | 0–2 | Super League · China |