| 2022-05-08 | PalmeirasvFluminenseSerie A · Brazil | 1–1 | Serie A · Brazil |
| 2022-05-08 | StromsgodsetvRosenborgEliteserien · Norway | 3–0 | Eliteserien · Norway |
| 2022-05-08 | Univ. CraiovavFCSBSuperliga · Romania | 0–1 | Superliga · Romania |
| 2022-05-08 | JuventudevInternacionalSerie A · Brazil | 1–1 | Serie A · Brazil |
| 2022-05-08 | Sp BragavAroucaPrimeira Liga · Portugal | 1–0 | Primeira Liga · Portugal |
| 2022-05-08 | SpeziavAtalantaSerie A · Italy | 1–3 | Serie A · Italy |
| 2022-05-08 | Santa ClaravPacos FerreiraPrimeira Liga · Portugal | 2–0 | Primeira Liga · Portugal |
| 2022-05-08 | Vancouver WhitecapsvToronto FCMLS · United States | 1–0 | MLS · United States |
| 2022-05-08 | SalernitanavCagliariSerie A · Italy | 1–1 | Serie A · Italy |
| 2022-05-08 | VizelavMaritimoPrimeira Liga · Portugal | 1–1 | Primeira Liga · Portugal |
| 2022-05-08 | A. KlagenfurtvSturm GrazBundesliga · Austria | 1–2 | Bundesliga · Austria |
| 2022-05-08 | Sepsi Sf. GheorghevChindia TargovisteSuperliga · Romania | 2–1 | Superliga · Romania |
| 2022-05-08 | GrasshoppersvSionSuper League · Switzerland | 0–1 | Super League · Switzerland |
| 2022-05-08 | LorientvMarseilleLigue 1 · France | 0–3 | Ligue 1 · France |
| 2022-05-08 | RangersvDundee UnitedPremiership · Scotland | 2–0 | Premiership · Scotland |
| 2022-05-08 | New England RevolutionvColumbus CrewMLS · United States | 2–2 | MLS · United States |
| 2022-05-08 | IbizavLugoLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2022-05-08 | ArisvOlympiakosSuper League · Greece | 0–1 | Super League · Greece |
| 2022-05-08 | New York CityvSporting Kansas CityMLS · United States | 0–0 | MLS · United States |
| 2022-05-08 | Kashiwa ReysolvUrawa RedsJ1 League · Japan | 0–0 | J1 League · Japan |
| 2022-05-08 | Gamba OsakavVissel KobeJ1 League · Japan | 2–0 | J1 League · Japan |
| 2022-05-08 | RakowvCracoviaEkstraklasa · Poland | 1–1 | Ekstraklasa · Poland |
| 2022-05-08 | LausannevBaselSuper League · Switzerland | 0–0 | Super League · Switzerland |
| 2022-05-08 | VillarrealvSevillaLa Liga · Spain | 1–1 | La Liga · Spain |
| 2022-05-08 | WrexhamvStockportNational League · England | 3–0 | National League · England |
| 2022-05-08 | Lechia GdanskvStal MielecEkstraklasa · Poland | 3–2 | Ekstraklasa · Poland |
| 2022-05-08 | Nashville SCvReal Salt LakeMLS · United States | 2–0 | MLS · United States |
| 2022-05-08 | AngersvBordeauxLigue 1 · France | 4–1 | Ligue 1 · France |
| 2022-05-08 | CartagenavLeganesLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2022-05-08 | NorwichvWest HamPremier League · England | 0–4 | Premier League · England |
| 2022-05-08 | Talleres CordobavSarmiento JuninCopa De La Liga Profesional · Argentina | 1–0 | Copa De La Liga Profesional · Argentina |
| 2022-05-08 | MonterreyvAtl. San LuisLiga MX · Mexico | 2–2 | Liga MX · Mexico |
| 2022-05-08 | FC DallasvSeattle SoundersMLS · United States | 2–0 | MLS · United States |
| 2022-05-08 | Paris SGvTroyesLigue 1 · France | 2–2 | Ligue 1 · France |
| 2022-05-08 | SantosvCuiabaSerie A · Brazil | 4–1 | Serie A · Brazil |
| 2022-05-08 | DC UnitedvHouston DynamoMLS · United States | 2–0 | MLS · United States |
| 2022-05-08 | FortalezavSao PauloSerie A · Brazil | 1–1 | Serie A · Brazil |
| 2022-05-08 | KarlsruhevDresden2. Bundesliga · Germany | 2–2 | 2. Bundesliga · Germany |
| 2022-05-08 | BesiktasvFenerbahceSüper Lig · Turkey | 1–1 | Süper Lig · Turkey |
| 2022-05-08 | FC TokyovSagan TosuJ1 League · Japan | 0–1 | J1 League · Japan |
| 2022-05-08 | Bayern MunichvStuttgartBundesliga · Germany | 2–2 | Bundesliga · Germany |
| 2022-05-08 | ArsenalvLeedsPremier League · England | 2–1 | Premier League · England |
| 2022-05-08 | Austria ViennavSK RapidBundesliga · Austria | 1–1 | Bundesliga · Austria |
| 2022-05-07 | SwanseavQPRChampionship · England | 0–1 | Championship · England |
| 2022-05-07 | HartlepoolvColchesterLeague Two · England | 0–2 | League Two · England |
| 2022-05-07 | UralvSpartak MoscowPremier League · Russia | 1–3 | Premier League · Russia |
| 2022-05-07 | SassuolovUdineseSerie A · Italy | 1–1 | Serie A · Italy |
| 2022-05-07 | ChelseavWolvesPremier League · England | 2–2 | Premier League · England |
| 2022-05-07 | Hokkaido Consadole SapporovKyotoJ1 League · Japan | 1–0 | J1 League · Japan |
| 2022-05-07 | Schalke 04vSt Pauli2. Bundesliga · Germany | 3–2 | 2. Bundesliga · Germany |