| 2010-01-24 | CordobavCastellonLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2010-01-24 | WolfsburgvFC KolnBundesliga · Germany | 2–3 | Bundesliga · Germany |
| 2010-01-24 | PanthrakikosvXanthiSuper League · Greece | 1–1 | Super League · Greece |
| 2010-01-24 | GenkvClub BruggePro League · Belgium | 2–0 | Pro League · Belgium |
| 2010-01-24 | OberhausenvAugsburg2. Bundesliga · Germany | 0–3 | 2. Bundesliga · Germany |
| 2010-01-24 | KayserisporvGenclerbirligiSüper Lig · Turkey | 1–1 | Süper Lig · Turkey |
| 2010-01-24 | HuescavCeltaLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2010-01-24 | SociedadvElcheLa Liga 2 · Spain | 0–1 | La Liga 2 · Spain |
| 2010-01-24 | EspanolvMallorcaLa Liga · Spain | 1–1 | La Liga · Spain |
| 2010-01-24 | GroningenvTwenteEredivisie · Netherlands | 0–0 | Eredivisie · Netherlands |
| 2010-01-24 |  Ivory Coastv AlgeriaAfrican Cup of Nations | 2–3 | African Cup of Nations |
| 2010-01-24 | XerezvOsasunaLa Liga · Spain | 1–2 | La Liga · Spain |
| 2010-01-24 | SpartavDen HaagEredivisie · Netherlands | 0–0 | Eredivisie · Netherlands |
| 2010-01-24 | LivornovNapoliSerie A · Italy | 0–2 | Serie A · Italy |
| 2010-01-24 | FalkirkvDundee UnitedPremiership · Scotland | 1–4 | Premiership · Scotland |
| 2010-01-24 | TrabzonsporvSivassporSüper Lig · Turkey | 3–1 | Süper Lig · Turkey |
| 2010-01-24 | LaziovChievoSerie A · Italy | 1–1 | Serie A · Italy |
| 2010-01-24 | KarlsruhevPaderborn2. Bundesliga · Germany | 1–2 | 2. Bundesliga · Germany |
| 2010-01-23 | Milton Keynes DonsvTranmereLeague One · England | 1–0 | League One · England |
| 2010-01-23 | ClydevBrechinLeague One · Scotland | 0–3 | League One · Scotland |
| 2010-01-23 | CesenavGallipoliSerie B · Italy | 0–0 | Serie B · Italy |
| 2010-01-23 | RotherhamvGrimsbyLeague Two · England | 2–1 | League Two · England |
| 2010-01-23 | Roda JCvUtrechtEredivisie · Netherlands | 2–0 | Eredivisie · Netherlands |
| 2010-01-23 | HeraclesvVitesseEredivisie · Netherlands | 1–2 | Eredivisie · Netherlands |
| 2010-01-23 | LokerenvRoeselarePro League · Belgium | 1–4 | Pro League · Belgium |
| 2010-01-23 | AltrinchamvHayes & YeadingNational League · England | 3–2 | National League · England |
| 2010-01-23 | AscolivModenaSerie B · Italy | 2–0 | Serie B · Italy |
| 2010-01-23 | DortmundvHamburgBundesliga · Germany | 1–0 | Bundesliga · Germany |
| 2010-01-23 | ShrewsburyvDag and RedLeague Two · England | 2–1 | League Two · England |
| 2010-01-23 | CambridgevYorkNational League · England | 0–1 | National League · England |
| 2010-01-23 | NurnbergvEin FrankfurtBundesliga · Germany | 1–1 | Bundesliga · Germany |
| 2010-01-23 | KortrijkvGerminalPro League · Belgium | 3–0 | Pro League · Belgium |
| 2010-01-23 | AldershotvBournemouthLeague Two · England | 2–1 | League Two · England |
| 2010-01-23 | St PaulivAachen2. Bundesliga · Germany | 1–0 | 2. Bundesliga · Germany |
| 2010-01-23 | WaregemvSt TruidenPro League · Belgium | 2–0 | Pro League · Belgium |
| 2010-01-23 | LarisavIraklisSuper League · Greece | 2–1 | Super League · Greece |
| 2010-01-23 | SalamancavVillarreal BLa Liga 2 · Spain | 2–4 | La Liga 2 · Spain |
| 2010-01-23 | StenhousemuirvAlloaLeague One · Scotland | 0–2 | League One · Scotland |
| 2010-01-23 | MotherwellvSt MirrenPremiership · Scotland | 2–0 | Premiership · Scotland |
| 2010-01-23 | WrexhamvAFC WimbledonNational League · England | 1–0 | National League · England |
| 2010-01-23 | Airdrie UtdvInverness CChampionship · Scotland | 0–1 | Championship · Scotland |
| 2010-01-23 | SassuolovVicenzaSerie B · Italy | 2–1 | Serie B · Italy |
| 2010-01-23 | GillinghamvColchesterLeague One · England | 0–0 | League One · England |
| 2010-01-23 | Raith RvsvMortonChampionship · Scotland | 1–2 | Championship · Scotland |
| 2010-01-23 | La CorunavAth BilbaoLa Liga · Spain | 3–1 | La Liga · Spain |
| 2010-01-23 | RangersvHeartsPremiership · Scotland | 1–1 | Premiership · Scotland |
| 2010-01-23 | CataniavParmaSerie A · Italy | 3–0 | Serie A · Italy |
| 2010-01-23 | MontrosevEast StirlingLeague Two · Scotland | 0–1 | League Two · Scotland |
| 2010-01-23 | BresciavCrotoneSerie B · Italy | 3–0 | Serie B · Italy |
| 2010-01-23 | Werder BremenvBayern MunichBundesliga · Germany | 2–3 | Bundesliga · Germany |