| 2000-01-22 | DumbartonvCowdenbeathLeague Two · Scotland | 2–0 | League Two · Scotland |
| 2000-01-22 | Sheffield UnitedvMan CityChampionship · England | 1–0 | Championship · England |
| 2000-01-22 | Port ValevBirminghamChampionship · England | 3–1 | Championship · England |
| 2000-01-22 | LeganesvAth Madrid BLa Liga 2 · Spain | 0–1 | La Liga 2 · Spain |
| 2000-01-22 | BradfordvWatfordPremier League · England | 3–2 | Premier League · England |
| 2000-01-22 | RomavPiacenzaSerie A · Italy | 2–1 | Serie A · Italy |
| 2000-01-22 | Nott'm ForestvWest BromChampionship · England | 0–0 | Championship · England |
| 2000-01-22 | CampomaiorensevGil VicentePrimeira Liga · Portugal | 0–0 | Primeira Liga · Portugal |
| 2000-01-22 | GuimaraesvSetubalPrimeira Liga · Portugal | 4–0 | Primeira Liga · Portugal |
| 2000-01-22 | TottenhamvSheffield WedsPremier League · England | 0–1 | Premier League · England |
| 2000-01-22 | GillinghamvBlackpoolLeague One · England | 1–3 | League One · England |
| 2000-01-22 | East FifevQueens ParkLeague Two · Scotland | 0–0 | League Two · Scotland |
| 2000-01-22 | ScunthorpevNotts CountyLeague One · England | 1–0 | League One · England |
| 2000-01-22 | HullvCheltenhamLeague Two · England | 1–1 | League Two · England |
| 2000-01-22 | MechelenvMouscronPro League · Belgium | 1–3 | Pro League · Belgium |
| 2000-01-22 | RochdalevYorkLeague Two · England | 2–1 | League Two · England |
| 2000-01-22 | RotherhamvExeterLeague Two · England | 5–0 | League Two · England |
| 2000-01-22 | La CorunavBetisLa Liga · Spain | 2–0 | La Liga · Spain |
| 2000-01-22 | Dundee UnitedvHibernianPremiership · Scotland | 0–0 | Premiership · Scotland |
| 2000-01-22 | FalkirkvSt MirrenChampionship · Scotland | 2–0 | Championship · Scotland |
| 2000-01-22 | ClydevHamiltonLeague One · Scotland | 1–0 | League One · Scotland |
| 2000-01-22 | Albion RvsvEast StirlingLeague Two · Scotland | 0–1 | League Two · Scotland |
| 2000-01-22 | LleidavLevanteLa Liga 2 · Spain | 2–0 | La Liga 2 · Spain |
| 2000-01-22 | CrewevWalsallChampionship · England | 2–3 | Championship · England |
| 2000-01-22 | MortonvAirdrieChampionship · Scotland | 4–0 | Championship · Scotland |
| 2000-01-22 | LokerenvSt TruidenPro League · Belgium | 3–0 | Pro League · Belgium |
| 2000-01-22 | Leyton OrientvPeterboroLeague Two · England | 1–1 | League Two · England |
| 2000-01-22 | FulhamvGrimsbyChampionship · England | 0–1 | Championship · England |
| 2000-01-22 | CambridgevChesterfieldLeague One · England | 2–0 | League One · England |
| 2000-01-22 | SouthamptonvEvertonPremier League · England | 2–0 | Premier League · England |
| 2000-01-22 | NorthamptonvChesterLeague Two · England | 3–1 | League Two · England |
| 2000-01-22 | BoltonvIpswichChampionship · England | 1–1 | Championship · England |
| 2000-01-22 | GenkvGeelPro League · Belgium | 1–0 | Pro League · Belgium |
| 2000-01-22 | OxfordvBristol RvsLeague One · England | 0–5 | League One · England |
| 2000-01-22 | GaziantepsporvAdanasporSüper Lig · Turkey | 1–1 | Süper Lig · Turkey |
| 2000-01-22 | PartickvRoss CountyLeague One · Scotland | 4–2 | League One · Scotland |
| 2000-01-22 | NorwichvCharltonChampionship · England | 0–3 | Championship · England |
| 2000-01-22 | BrentfordvBuryLeague One · England | 2–1 | League One · England |
| 2000-01-22 | WimbledonvNewcastlePremier League · England | 2–0 | Premier League · England |
| 2000-01-22 | TorquayvBrightonLeague Two · England | 0–0 | League Two · England |
| 2000-01-22 | Inverness CvRaith RvsChampionship · Scotland | 1–1 | Championship · Scotland |
| 2000-01-22 | MontrosevForfarLeague Two · Scotland | 1–5 | League Two · Scotland |
| 2000-01-22 | BenficavRio AvePrimeira Liga · Portugal | 1–0 | Primeira Liga · Portugal |
| 2000-01-22 | BurnleyvOldhamLeague One · England | 3–0 | League One · England |
| 2000-01-22 | BarnetvLincolnLeague Two · England | 5–3 | League Two · England |
| 2000-01-22 | LutonvReadingLeague One · England | 3–1 | League One · England |
| 2000-01-22 |  Ghanav CameroonAfrican Cup of Nations | 1–1 | African Cup of Nations |
| 2000-01-22 | LivingstonvClydebankChampionship · Scotland | 3–0 | Championship · Scotland |
| 2000-01-22 | HuddersfieldvTranmereChampionship · England | 1–0 | Championship · England |
| 2000-01-22 | StockportvPortsmouthChampionship · England | 1–1 | Championship · England |