| 2010-01-30 | NAC BredavVVV VenloEredivisie · Netherlands | 2–0 | Eredivisie · Netherlands |
| 2010-01-30 | NavalvBelenensesPrimeira Liga · Portugal | 1–0 | Primeira Liga · Portugal |
| 2010-01-30 | RangersvFalkirkPremiership · Scotland | 3–0 | Premiership · Scotland |
| 2010-01-30 | Port ValevHerefordLeague Two · England | 2–0 | League Two · England |
| 2010-01-30 | LeedsvColchesterLeague One · England | 2–0 | League One · England |
| 2010-01-30 | LevantevVillarreal BLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2010-01-30 | VannesvGuingampLigue 2 · France | 2–2 | Ligue 2 · France |
| 2010-01-30 | DundeevRoss CountyChampionship · Scotland | 0–1 | Championship · Scotland |
| 2010-01-30 | IraklisvKavalaSuper League · Greece | 1–0 | Super League · Greece |
| 2010-01-30 | CardiffvDoncasterChampionship · England | 2–1 | Championship · England |
| 2010-01-30 | Bristol RvsvWycombeLeague One · England | 2–3 | League One · England |
| 2010-01-30 | NapolivGenoaSerie A · Italy | 0–0 | Serie A · Italy |
| 2010-01-30 | CarlislevLeyton OrientLeague One · England | 2–2 | League One · England |
| 2010-01-30 | DiyarbakirsporvTrabzonsporSüper Lig · Turkey | 1–2 | Süper Lig · Turkey |
| 2010-01-30 | NorthamptonvBurtonLeague Two · England | 1–1 | League Two · England |
| 2010-01-30 | SassuolovSalernitanaSerie B · Italy | 3–2 | Serie B · Italy |
| 2010-01-30 | Le MansvToulouseLigue 1 · France | 1–3 | Ligue 1 · France |
| 2010-01-30 | West HamvBlackburnPremier League · England | 0–0 | Premier League · England |
| 2010-01-30 | HuescavElcheLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2010-01-30 | East StirlingvStranraerLeague Two · Scotland | 2–0 | League Two · Scotland |
| 2010-01-30 | EspanolvAth BilbaoLa Liga · Spain | 1–0 | La Liga · Spain |
| 2010-01-30 | HullvWolvesPremier League · England | 2–2 | Premier League · England |
| 2010-01-30 | SouthendvSwindonLeague One · England | 2–2 | League One · England |
| 2010-01-30 | SociedadvLas PalmasLa Liga 2 · Spain | 2–2 | La Liga 2 · Spain |
| 2010-01-30 | GianninavLarisaSuper League · Greece | 2–0 | Super League · Greece |
| 2010-01-30 | BurnleyvChelseaPremier League · England | 1–2 | Premier League · England |
| 2010-01-30 | Forest GreenvMansfieldNational League · England | 1–4 | National League · England |
| 2010-01-30 | Bayern MunichvMainzBundesliga · Germany | 3–0 | Bundesliga · Germany |
| 2010-01-30 | NacionalvPortoPrimeira Liga · Portugal | 0–4 | Primeira Liga · Portugal |
| 2010-01-30 | BenficavGuimaraesPrimeira Liga · Portugal | 3–1 | Primeira Liga · Portugal |
| 2010-01-30 | AldershotvGrimsbyLeague Two · England | 1–1 | League Two · England |
| 2010-01-30 | FulhamvAston VillaPremier League · England | 0–2 | Premier League · England |
| 2010-01-30 | BrechinvStenhousemuirLeague One · Scotland | 2–2 | League One · Scotland |
| 2010-01-30 |  MonacovNiceLigue 1 · France | 3–2 | Ligue 1 · France |
| 2010-01-30 | Den HaagvHeerenveenEredivisie · Netherlands | 2–1 | Eredivisie · Netherlands |
| 2010-01-30 | MantovavCrotoneSerie B · Italy | 2–1 | Serie B · Italy |
| 2010-01-30 | AlbacetevVallecanoLa Liga 2 · Spain | 2–2 | La Liga 2 · Spain |
| 2010-01-30 | NorwichvHartlepoolLeague One · England | 2–1 | League One · England |
| 2010-01-30 | BerwickvMontroseLeague Two · Scotland | 0–2 | League Two · Scotland |
| 2010-01-30 | M'gladbachvWerder BremenBundesliga · Germany | 4–3 | Bundesliga · Germany |
| 2010-01-30 | AugsburgvBielefeld2. Bundesliga · Germany | 3–1 | 2. Bundesliga · Germany |
| 2010-01-30 | TriestinavPiacenzaSerie B · Italy | 1–3 | Serie B · Italy |
| 2010-01-30 | Crystal PalacevPeterboroChampionship · England | 2–0 | Championship · England |
| 2010-01-30 | HamiltonvCelticPremiership · Scotland | 0–1 | Premiership · Scotland |
| 2010-01-30 | CartagenavGironaLa Liga 2 · Spain | 4–1 | La Liga 2 · Spain |
| 2010-01-30 | CrewevBournemouthLeague Two · England | 1–2 | League Two · England |
| 2010-01-30 | RennesvGrenobleLigue 1 · France | 4–0 | Ligue 1 · France |
| 2010-01-30 | BuyuksehyrvKasimpasaSüper Lig · Turkey | 4–2 | Süper Lig · Turkey |
| 2010-01-29 | GerminalvAnderlechtPro League · Belgium | 0–5 | Pro League · Belgium |
| 2010-01-29 | Willem IIvWaalwijkEredivisie · Netherlands | 2–1 | Eredivisie · Netherlands |