| 2010-01-30 | MorecambevChesterfieldLeague Two · England | 0–1 | League Two · England |
| 2010-01-30 | Hayes & YeadingvRushden & DNational League · England | 1–6 | National League · England |
| 2010-01-30 | ShrewsburyvAccringtonLeague Two · England | 0–1 | League Two · England |
| 2010-01-30 | Milton Keynes DonsvExeterLeague One · England | 1–1 | League One · England |
| 2010-01-30 | LiverpoolvBoltonPremier League · England | 2–0 | Premier League · England |
| 2010-01-30 | SouthamptonvStockportLeague One · England | 2–0 | League One · England |
| 2010-01-30 | LeicestervNewcastleChampionship · England | 0–0 | Championship · England |
| 2010-01-30 | CoventryvBlackpoolChampionship · England | 1–1 | Championship · England |
| 2010-01-30 | HerthavBochumBundesliga · Germany | 0–0 | Bundesliga · Germany |
| 2010-01-30 | CittadellavAnconaSerie B · Italy | 1–0 | Serie B · Italy |
| 2010-01-30 | AltrinchamvWrexhamNational League · England | 1–3 | National League · England |
| 2010-01-30 | AlloavArbroathLeague One · Scotland | 1–0 | League One · Scotland |
| 2010-01-30 | Sp GijonvBarcelonaLa Liga · Spain | 0–1 | La Liga · Spain |
| 2010-01-30 | NijmegenvSpartaEredivisie · Netherlands | 1–0 | Eredivisie · Netherlands |
| 2010-01-30 | BarivPalermoSerie A · Italy | 4–2 | Serie A · Italy |
| 2010-01-30 | Schalke 04vHoffenheimBundesliga · Germany | 2–0 | Bundesliga · Germany |
| 2010-01-30 | LutonvEbbsfleetNational League · England | 2–3 | National League · England |
| 2010-01-30 | HibernianvSt MirrenPremiership · Scotland | 2–1 | Premiership · Scotland |
| 2010-01-30 | WiganvEvertonPremier League · England | 0–1 | Premier League · England |
| 2010-01-30 | CharltonvTranmereLeague One · England | 1–1 | League One · England |
| 2010-01-30 | Ein FrankfurtvFC KolnBundesliga · Germany | 1–2 | Bundesliga · Germany |
| 2010-01-30 | Sheffield WedsvPlymouthChampionship · England | 2–1 | Championship · England |
| 2010-01-30 | PAOKvAtromitosSuper League · Greece | 1–0 | Super League · Greece |
| 2010-01-30 | West BromvSheffield UnitedChampionship · England | 3–1 | Championship · England |
| 2010-01-30 | Club BruggevWesterloPro League · Belgium | 2–1 | Pro League · Belgium |
| 2010-01-30 |  Nigeriav AlgeriaAfrican Cup of Nations | 1–0 | African Cup of Nations |
| 2010-01-30 | MiddlesbroughvBristol CityChampionship · England | 0–0 | Championship · England |
| 2010-01-30 | TorquayvBradfordLeague Two · England | 1–2 | League Two · England |
| 2010-01-30 | QPRvScunthorpeChampionship · England | 0–1 | Championship · England |
| 2010-01-30 | GillinghamvWalsallLeague One · England | 0–0 | League One · England |
| 2010-01-30 | BirminghamvTottenhamPremier League · England | 1–1 | Premier League · England |
| 2010-01-30 | KilmarnockvDundee UnitedPremiership · Scotland | 4–4 | Premiership · Scotland |
| 2010-01-30 | NancyvLorientLigue 1 · France | 1–0 | Ligue 1 · France |
| 2010-01-30 | MontpelliervMarseilleLigue 1 · France | 2–0 | Ligue 1 · France |
| 2010-01-30 | HerculesvCastellonLa Liga 2 · Spain | 1–2 | La Liga 2 · Spain |
| 2010-01-30 | La CorunavReal MadridLa Liga · Spain | 1–3 | La Liga · Spain |
| 2010-01-30 | MechelenvCercle BruggePro League · Belgium | 1–2 | Pro League · Belgium |
| 2010-01-30 | Notts CountyvBarnetLeague Two · England | 2–0 | League Two · England |
| 2010-01-30 | HannovervNurnbergBundesliga · Germany | 1–3 | Bundesliga · Germany |
| 2010-01-30 | LillevLensLigue 1 · France | 1–0 | Ligue 1 · France |
| 2010-01-30 | BordeauxvBoulogneLigue 1 · France | 0–0 | Ligue 1 · France |
| 2010-01-30 | ReadingvBarnsleyChampionship · England | 1–0 | Championship · England |
| 2010-01-30 | AZ AlkmaarvGroningenEredivisie · Netherlands | 0–1 | Eredivisie · Netherlands |
| 2010-01-30 | PrestonvIpswichChampionship · England | 2–0 | Championship · England |
| 2010-01-30 | AberdeenvMotherwellPremiership · Scotland | 0–3 | Premiership · Scotland |
| 2010-01-30 | LeiriavOlhanensePrimeira Liga · Portugal | 2–0 | Primeira Liga · Portugal |
| 2010-01-30 | Inverness CvPartickChampionship · Scotland | 2–1 | Championship · Scotland |
| 2010-01-30 | YeovilvHuddersfieldLeague One · England | 0–1 | League One · England |
| 2010-01-30 | BrightonvMillwallLeague One · England | 0–1 | League One · England |
| 2010-01-30 | DerbyvNott'm ForestChampionship · England | 1–0 | Championship · England |