| 2016-05-15 | HuescavAlmeriaLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2016-05-15 | SalzburgvWolfsberger ACBundesliga · Austria | 1–0 | Bundesliga · Austria |
| 2016-05-15 | OdensevHobroSuperliga · Denmark | 0–1 | Superliga · Denmark |
| 2016-05-15 | ComovSpeziaSerie B · Italy | 4–0 | Serie B · Italy |
| 2016-05-15 | Toronto FCvVancouver WhitecapsMLS · United States | 3–4 | MLS · United States |
| 2016-05-15 | Santa CruzvVitoriaSerie A · Brazil | 4–1 | Serie A · Brazil |
| 2016-05-15 | MattersburgvGrodigBundesliga · Austria | 2–3 | Bundesliga · Austria |
| 2016-05-15 | NewcastlevTottenhamPremier League · England | 5–1 | Premier League · England |
| 2016-05-15 | LegiavPogon SzczecinEkstraklasa · Poland | 3–0 | Ekstraklasa · Poland |
| 2016-05-15 | FC DallasvSeattle SoundersMLS · United States | 2–0 | MLS · United States |
| 2016-05-15 | EvertonvNorwichPremier League · England | 3–0 | Premier League · England |
| 2016-05-15 | Club LeonvMonarcasLiga MX · Mexico | 4–1 | Liga MX · Mexico |
| 2016-05-15 | MoreirensevMaritimoPrimeira Liga · Portugal | 2–1 | Primeira Liga · Portugal |
| 2016-05-15 | VallecanovLevanteLa Liga · Spain | 3–1 | La Liga · Spain |
| 2016-05-15 | SouthamptonvCrystal PalacePremier League · England | 4–1 | Premier League · England |
| 2016-05-15 | Hangzhou GreentownvLiaoningSuper League · China | 0–0 | Super League · China |
| 2016-05-15 | BesiktasvOsmanlisporSüper Lig · Turkey | 3–1 | Süper Lig · Turkey |
| 2016-05-15 | HeartsvSt JohnstonePremiership · Scotland | 2–2 | Premiership · Scotland |
| 2016-05-14 | WolfsburgvStuttgartBundesliga · Germany | 3–1 | Bundesliga · Germany |
| 2016-05-14 | JerseyvGuernseyMuratti Vase | 1–0 | Muratti Vase |
| 2016-05-14 | MidtjyllandvSonderjyskeSuperliga · Denmark | 3–2 | Superliga · Denmark |
| 2016-05-14 | Vegalta SendaivOmiya ArdijaJ1 League · Japan | 0–1 | J1 League · Japan |
| 2016-05-14 | Ath MadridvCeltaLa Liga · Spain | 2–0 | La Liga · Spain |
| 2016-05-14 | Slask WroclawvLecznaEkstraklasa · Poland | 3–2 | Ekstraklasa · Poland |
| 2016-05-14 | Termalica B-B.vGornik Z.Ekstraklasa · Poland | 1–1 | Ekstraklasa · Poland |
| 2016-05-14 | St EtiennevLilleLigue 1 · France | 0–1 | Ligue 1 · France |
| 2016-05-14 | Atl. TucumanvSan Martin S.J.Liga Profesional · Argentina | 3–2 | Liga Profesional · Argentina |
| 2016-05-14 | GranadavBarcelonaLa Liga · Spain | 0–3 | La Liga · Spain |
| 2016-05-14 | Atletico-MGvSantosSerie A · Brazil | 1–0 | Serie A · Brazil |
| 2016-05-14 | Guangzhou EvergrandevHebeiSuper League · China | 2–0 | Super League · China |
| 2016-05-14 | KofuvNagoya GrampusJ1 League · Japan | 2–2 | J1 League · Japan |
| 2016-05-14 | KilmarnockvDundee UnitedPremiership · Scotland | 2–4 | Premiership · Scotland |
| 2016-05-14 | Flamengo RJvSport RecifeSerie A · Brazil | 1–0 | Serie A · Brazil |
| 2016-05-14 | BelenensesvEstorilPrimeira Liga · Portugal | 2–1 | Primeira Liga · Portugal |
| 2016-05-14 | CesenavNovaraSerie B · Italy | 1–0 | Serie B · Italy |
| 2016-05-14 | TroyesvMarseilleLigue 1 · France | 1–1 | Ligue 1 · France |
| 2016-05-14 | PartickvHamiltonPremiership · Scotland | 2–2 | Premiership · Scotland |
| 2016-05-14 | LorientvAjaccio GFCOLigue 1 · France | 1–0 | Ligue 1 · France |
| 2016-05-14 | Jiangsu SuningvShijiazhuangSuper League · China | 0–0 | Super League · China |
| 2016-05-14 | AngersvToulouseLigue 1 · France | 2–3 | Ligue 1 · France |
| 2016-05-14 | Godoy CruzvBelgranoLiga Profesional · Argentina | 1–0 | Liga Profesional · Argentina |
| 2016-05-14 | AugsburgvHamburgBundesliga · Germany | 1–3 | Bundesliga · Germany |
| 2016-05-14 | CaenvBordeauxLigue 1 · France | 1–0 | Ligue 1 · France |
| 2016-05-14 | Kashima AntlersvYokohama F. MarinosJ1 League · Japan | 1–0 | J1 League · Japan |
| 2016-05-14 | Uniao MadeiravRio AvePrimeira Liga · Portugal | 1–2 | Primeira Liga · Portugal |
| 2016-05-14 | Henan Songshan LongmenvTianjin Jinmen TigerSuper League · China | 0–0 | Super League · China |
| 2016-05-14 | Kawasaki FrontalevVissel KobeJ1 League · Japan | 3–1 | J1 League · Japan |
| 2016-05-14 | Ath BilbaovSevillaLa Liga · Spain | 3–1 | La Liga · Spain |
| 2016-05-14 | ReimsvLyonLigue 1 · France | 4–1 | Ligue 1 · France |
| 2016-05-14 | NapolivFrosinoneSerie A · Italy | 4–0 | Serie A · Italy |