| 2000-02-05 | Ross CountyvQueen of SthLeague One · Scotland | 2–0 | League One · Scotland |
| 2000-02-05 | NijmegenvGraafschapEredivisie · Netherlands | 2–3 | Eredivisie · Netherlands |
| 2000-02-05 | GentvMouscronPro League · Belgium | 2–3 | Pro League · Belgium |
| 2000-02-05 | PrestonvReadingLeague One · England | 2–2 | League One · England |
| 2000-02-05 | Sheffield UnitedvTranmereChampionship · England | 3–1 | Championship · England |
| 2000-02-05 | BurnleyvBristol RvsLeague One · England | 1–0 | League One · England |
| 2000-02-05 | LiverpoolvLeedsPremier League · England | 3–1 | Premier League · England |
| 2000-02-05 | BielefeldvSchalke 04Bundesliga · Germany | 1–2 | Bundesliga · Germany |
| 2000-02-05 | TroyesvSedanLigue 1 · France | 0–2 | Ligue 1 · France |
| 2000-02-05 | WolvesvCrystal PalaceChampionship · England | 2–1 | Championship · England |
| 2000-02-05 | CaenvLorientLigue 2 · France | 1–2 | Ligue 2 · France |
| 2000-02-05 | MontpelliervLe HavreLigue 1 · France | 0–0 | Ligue 1 · France |
| 2000-02-05 | ValenciavBetisLa Liga · Spain | 3–1 | La Liga · Spain |
| 2000-02-05 | BastiavSt EtienneLigue 1 · France | 4–0 | Ligue 1 · France |
| 2000-02-05 | ColchestervBuryLeague One · England | 1–3 | League One · England |
| 2000-02-05 | HullvBrightonLeague Two · England | 2–0 | League Two · England |
| 2000-02-05 | St MirrenvLivingstonChampionship · Scotland | 0–2 | Championship · Scotland |
| 2000-02-05 | CambridgevWiganLeague One · England | 1–1 | League One · England |
| 2000-02-05 | ClydebankvDunfermlineChampionship · Scotland | 1–3 | Championship · Scotland |
| 2000-02-05 | SouthamptonvWest HamPremier League · England | 2–1 | Premier League · England |
| 2000-02-05 | LutonvBournemouthLeague One · England | 1–2 | League One · England |
| 2000-02-05 | SunderlandvNewcastlePremier League · England | 2–2 | Premier League · England |
| 2000-02-05 | CreteilvNiceLigue 2 · France | 0–0 | Ligue 2 · France |
| 2000-02-05 | CowdenbeathvAlbion RvsLeague Two · Scotland | 5–0 | League Two · Scotland |
| 2000-02-05 | Munich 1860vWolfsburgBundesliga · Germany | 1–2 | Bundesliga · Germany |
| 2000-02-05 | HeerenveenvAZ AlkmaarEredivisie · Netherlands | 3–0 | Eredivisie · Netherlands |
| 2000-02-05 | OxfordvBlackpoolLeague One · England | 0–1 | League One · England |
| 2000-02-05 | BordeauxvStrasbourgLigue 1 · France | 3–0 | Ligue 1 · France |
| 2000-02-05 | RotherhamvMacclesfieldLeague Two · England | 2–1 | League Two · England |
| 2000-02-05 | UdinesevJuventusSerie A · Italy | 1–1 | Serie A · Italy |
| 2000-02-05 | CrewevBirminghamChampionship · England | 2–3 | Championship · England |
| 2000-02-05 | Port ValevQPRChampionship · England | 1–1 | Championship · England |
| 2000-02-05 | MechelenvLiersePro League · Belgium | 4–3 | Pro League · Belgium |
| 2000-02-05 | PlymouthvCarlisleLeague Two · England | 2–0 | League Two · England |
| 2000-02-05 | Sp LisbonvFarensePrimeira Liga · Portugal | 3–1 | Primeira Liga · Portugal |
| 2000-02-05 | Bristol CityvChesterfieldLeague One · England | 3–0 | League One · England |
| 2000-02-05 | ForfarvDumbartonLeague Two · Scotland | 4–3 | League Two · Scotland |
| 2000-02-05 | Willem IIvTwenteEredivisie · Netherlands | 1–1 | Eredivisie · Netherlands |
| 2000-02-05 | SwindonvGrimsbyChampionship · England | 0–1 | Championship · England |
| 2000-02-05 | HartlepoolvShrewsburyLeague Two · England | 1–0 | League Two · England |
| 2000-02-05 | GenkvCharleroiPro League · Belgium | 1–2 | Pro League · Belgium |
| 2000-02-05 | BrechinvEast FifeLeague Two · Scotland | 3–1 | League Two · Scotland |
| 2000-02-05 | KocaelisporvFenerbahceSüper Lig · Turkey | 1–1 | Süper Lig · Turkey |
| 2000-02-05 | BrentfordvNotts CountyLeague One · England | 0–2 | League One · England |
| 2000-02-05 | FulhamvWest BromChampionship · England | 1–0 | Championship · England |
| 2000-02-05 | MaritimovSetubalPrimeira Liga · Portugal | 1–0 | Primeira Liga · Portugal |
| 2000-02-05 | LeicestervMiddlesbroughPremier League · England | 2–1 | Premier League · England |
| 2000-02-05 | LensvAuxerreLigue 1 · France | 2–1 | Ligue 1 · France |
| 2000-02-05 | TorquayvHalifaxLeague Two · England | 4–0 | League Two · England |
| 2000-02-05 | AyrvMortonChampionship · Scotland | 3–2 | Championship · Scotland |