| 2016-12-10 | HartlepoolvCambridgeLeague Two · England | 0–5 | League Two · England |
| 2016-12-10 | BradfordvCharltonLeague One · England | 0–0 | League One · England |
| 2016-12-10 | RochdalevScunthorpeLeague One · England | 3–2 | League One · England |
| 2016-12-10 | Port ValevNorthamptonLeague One · England | 2–3 | League One · England |
| 2016-12-10 | Inverness CvHamiltonPremiership · Scotland | 1–1 | Premiership · Scotland |
| 2016-12-10 | FrosinonevSalernitanaSerie B · Italy | 1–3 | Serie B · Italy |
| 2016-12-10 | LyngbyvSilkeborgSuperliga · Denmark | 1–1 | Superliga · Denmark |
| 2016-12-10 | AEKvLevadeiakosSuper League · Greece | 4–0 | Super League · Greece |
| 2016-12-10 | CheltenhamvExeterLeague Two · England | 1–3 | League Two · England |
| 2016-12-10 | AberdeenvSt JohnstonePremiership · Scotland | 0–0 | Premiership · Scotland |
| 2016-12-10 | Bayern MunichvWolfsburgBundesliga · Germany | 5–0 | Bundesliga · Germany |
| 2016-12-10 | BochumvMunich 18602. Bundesliga · Germany | 1–0 | 2. Bundesliga · Germany |
| 2016-12-10 | SampdoriavLazioSerie A · Italy | 1–2 | Serie A · Italy |
| 2016-12-10 | TemperleyvGodoy CruzLiga Profesional · Argentina | 1–0 | Liga Profesional · Argentina |
| 2016-12-10 | GimnasticvVallecanoLa Liga 2 · Spain | 0–1 | La Liga 2 · Spain |
| 2016-12-10 | Sheffield UnitedvSwindonLeague One · England | 4–0 | League One · England |
| 2016-12-10 | Velez SarsfieldvAtl. RafaelaLiga Profesional · Argentina | 2–0 | Liga Profesional · Argentina |
| 2016-12-10 | OxfordvOldhamLeague One · England | 1–1 | League One · England |
| 2016-12-10 | PlymouthvDoncasterLeague Two · England | 2–0 | League Two · England |
| 2016-12-10 | Notts CountyvWycombeLeague Two · England | 0–2 | League Two · England |
| 2016-12-10 | VaduzvLausanneSuper League · Switzerland | 1–1 | Super League · Switzerland |
| 2016-12-10 | LeicestervMan CityPremier League · England | 4–2 | Premier League · England |
| 2016-12-10 | OsasunavBarcelonaLa Liga · Spain | 0–3 | La Liga · Spain |
| 2016-12-10 | Las PalmasvLeganesLa Liga · Spain | 1–1 | La Liga · Spain |
| 2016-12-10 | LecznavTermalica B-B.Ekstraklasa · Poland | 3–0 | Ekstraklasa · Poland |
| 2016-12-10 | MattersburgvAdmiraBundesliga · Austria | 2–0 | Bundesliga · Austria |
| 2016-12-10 | HuddersfieldvBristol CityChampionship · England | 2–1 | Championship · England |
| 2016-12-10 | HerthavWerder BremenBundesliga · Germany | 0–1 | Bundesliga · Germany |
| 2016-12-10 | MansfieldvColchesterLeague Two · England | 0–0 | League Two · England |
| 2016-12-10 | HeerenveenvExcelsiorEredivisie · Netherlands | 2–1 | Eredivisie · Netherlands |
| 2016-12-10 | ZwollevWillem IIEredivisie · Netherlands | 0–0 | Eredivisie · Netherlands |
| 2016-12-10 | PeterborovChesterfieldLeague One · England | 5–2 | League One · England |
| 2016-12-10 | NijmegenvDen HaagEredivisie · Netherlands | 3–0 | Eredivisie · Netherlands |
| 2016-12-10 | StrasbourgvLensLigue 2 · France | 3–1 | Ligue 2 · France |
| 2016-12-10 | CrewevCrawley TownLeague Two · England | 0–2 | League Two · England |
| 2016-12-10 | BaselvSt. GallenSuper League · Switzerland | 1–0 | Super League · Switzerland |
| 2016-12-10 | Milton Keynes DonsvAFC WimbledonLeague One · England | 1–0 | League One · England |
| 2016-12-10 | Talleres CordobavNewells Old BoysLiga Profesional · Argentina | 1–1 | Liga Profesional · Argentina |
| 2016-12-10 | AvellinovBeneventoSerie B · Italy | 1–1 | Serie B · Italy |
| 2016-12-10 | DijonvMarseilleLigue 1 · France | 1–2 | Ligue 1 · France |
| 2016-12-10 | WolvesvFulhamChampionship · England | 4–4 | Championship · England |
| 2016-12-10 | PerugiavPro VercelliSerie B · Italy | 1–0 | Serie B · Italy |
| 2016-12-10 | Bristol RvsvBuryLeague One · England | 4–2 | League One · England |
| 2016-12-10 | Asteras TripolisvVeriaSuper League · Greece | 0–0 | Super League · Greece |
| 2016-12-10 | Bordeauxv MonacoLigue 1 · France | 0–4 | Ligue 1 · France |
| 2016-12-10 | IpswichvCardiffChampionship · England | 1–1 | Championship · England |
| 2016-12-10 | StevenagevBlackpoolLeague Two · England | 0–2 | League Two · England |
| 2016-12-10 | LillevMontpellierLigue 1 · France | 2–1 | Ligue 1 · France |
| 2016-12-10 | BarnsleyvNorwichChampionship · England | 2–1 | Championship · England |
| 2016-12-10 | BastiavMetzLigue 1 · France | 2–0 | Ligue 1 · France |