| 2000-12-03 | SociedadvLas PalmasLa Liga · Spain | 1–1 | La Liga · Spain |
| 2000-12-03 | CottbusvHansa RostockBundesliga · Germany | 1–0 | Bundesliga · Germany |
| 2000-12-03 | BolognavVicenzaSerie A · Italy | 1–1 | Serie A · Italy |
| 2000-12-03 | BetisvLeganesLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2000-12-02 | East StirlingvBrechinLeague Two · Scotland | 0–1 | League Two · Scotland |
| 2000-12-02 | AjacciovSochauxLigue 2 · France | 0–0 | Ligue 2 · France |
| 2000-12-02 | CelticvDunfermlinePremiership · Scotland | 3–1 | Premiership · Scotland |
| 2000-12-02 | WolfsburgvSchalke 04Bundesliga · Germany | 2–0 | Bundesliga · Germany |
| 2000-12-02 | WycombevBournemouthLeague One · England | 0–3 | League One · England |
| 2000-12-02 | CarlislevLincolnLeague Two · England | 1–1 | League Two · England |
| 2000-12-02 | StockportvSheffield UnitedChampionship · England | 0–2 | Championship · England |
| 2000-12-02 | U.Las PalmasvEibarLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2000-12-02 | IpswichvDerbyPremier League · England | 0–1 | Premier League · England |
| 2000-12-02 | OsnabruckvReutlingen2. Bundesliga · Germany | 0–2 | 2. Bundesliga · Germany |
| 2000-12-02 | Beira MarvAvesPrimeira Liga · Portugal | 1–0 | Primeira Liga · Portugal |
| 2000-12-02 | RotherhamvMillwallLeague One · England | 3–2 | League One · England |
| 2000-12-02 | StuttgartvDortmundBundesliga · Germany | 0–2 | Bundesliga · Germany |
| 2000-12-02 | Sheffield WedsvQPRChampionship · England | 5–2 | Championship · England |
| 2000-12-02 | MontrosevCowdenbeathLeague Two · Scotland | 1–2 | League Two · Scotland |
| 2000-12-02 | VallecanovSantanderLa Liga · Spain | 4–1 | La Liga · Spain |
| 2000-12-02 | PeterheadvAlbion RvsLeague Two · Scotland | 1–2 | League Two · Scotland |
| 2000-12-02 | ParmavAtalantaSerie A · Italy | 2–0 | Serie A · Italy |
| 2000-12-02 | AlloavRoss CountyChampionship · Scotland | 0–0 | Championship · Scotland |
| 2000-12-02 | YorkvShrewsburyLeague Two · England | 2–1 | League Two · England |
| 2000-12-02 | DumbartonvElginLeague Two · Scotland | 3–0 | League Two · Scotland |
| 2000-12-02 | GillinghamvBirminghamChampionship · England | 1–2 | Championship · England |
| 2000-12-02 | PanioniosvAEKSuper League · Greece | 2–0 | Super League · Greece |
| 2000-12-02 | SpartavGraafschapEredivisie · Netherlands | 2–1 | Eredivisie · Netherlands |
| 2000-12-02 | StokevLutonLeague One · England | 1–3 | League One · England |
| 2000-12-02 | ExetervPlymouthLeague Two · England | 0–2 | League Two · England |
| 2000-12-02 | MouscronvLokerenPro League · Belgium | 2–1 | Pro League · Belgium |
| 2000-12-02 | ValladolidvValenciaLa Liga · Spain | 0–0 | La Liga · Spain |
| 2000-12-02 | Le MansvAngersLigue 2 · France | 2–1 | Ligue 2 · France |
| 2000-12-02 | WolvesvBarnsleyChampionship · England | 2–0 | Championship · England |
| 2000-12-02 | DarlingtonvMansfieldLeague Two · England | 2–1 | League Two · England |
| 2000-12-02 | LiersevGerminalPro League · Belgium | 1–1 | Pro League · Belgium |
| 2000-12-02 | TroyesvBordeauxLigue 1 · France | 1–0 | Ligue 1 · France |
| 2000-12-02 | BradfordvCoventryPremier League · England | 2–1 | Premier League · England |
| 2000-12-02 | CeltavBarcelonaLa Liga · Spain | 3–3 | La Liga · Spain |
| 2000-12-02 | GentvStandardPro League · Belgium | 2–1 | Pro League · Belgium |
| 2000-12-02 | EspanolvLa CorunaLa Liga · Spain | 0–2 | La Liga · Spain |
| 2000-12-02 | CaenvLavalLigue 2 · France | 0–1 | Ligue 2 · France |
| 2000-12-02 | MetzvLyonLigue 1 · France | 0–0 | Ligue 1 · France |
| 2000-12-02 | KidderminstervMacclesfieldLeague Two · England | 2–1 | League Two · England |
| 2000-12-02 | OsasunavReal MadridLa Liga · Spain | 2–3 | La Liga · Spain |
| 2000-12-02 | Raith RvsvClydeChampionship · Scotland | 1–2 | Championship · Scotland |
| 2000-12-02 | Bristol CityvBuryLeague One · England | 4–1 | League One · England |
| 2000-12-02 | AberdeenvKilmarnockPremiership · Scotland | 1–2 | Premiership · Scotland |
| 2000-12-02 | HamiltonvEast FifeLeague Two · Scotland | 1–1 | League Two · Scotland |
| 2000-12-02 | PeterborovWrexhamLeague One · England | 1–0 | League One · England |