| 2021-07-25 | SantosvAtletico GOSerie A · Brazil | 0–1 | Serie A · Brazil |
| 2021-07-25 | UNAM PumasvAtlasLiga MX · Mexico | 0–0 | Liga MX · Mexico |
| 2021-07-25 | Minnesota UnitedvPortland TimbersMLS · United States | 2–1 | MLS · United States |
| 2021-07-25 | San Jose EarthquakesvHouston DynamoMLS · United States | 1–1 | MLS · United States |
| 2021-07-25 | Real Salt LakevColorado RapidsMLS · United States | 3–0 | MLS · United States |
| 2021-07-25 | HammarbyvNorrkopingAllsvenskan · Sweden | 2–1 | Allsvenskan · Sweden |
| 2021-07-25 | FCSBvUniv. CraiovaSuperliga · Romania | 4–1 | Superliga · Romania |
| 2021-07-25 | LuganovZurichSuper League · Switzerland | 0–2 | Super League · Switzerland |
| 2021-07-25 | Randers FCvOdenseSuperliga · Denmark | 1–1 | Superliga · Denmark |
| 2021-07-25 | CSKA MoscowvUfaPremier League · Russia | 1–0 | Premier League · Russia |
| 2021-07-25 | MariehamnvInter TurkuVeikkausliiga · Finland | 0–2 | Veikkausliiga · Finland |
| 2021-07-24 | LecznavCracoviaEkstraklasa · Poland | 1–1 | Ekstraklasa · Poland |
| 2021-07-24 | PachucavClub LeonLiga MX · Mexico | 4–0 | Liga MX · Mexico |
| 2021-07-24 | SK RapidvHartbergBundesliga · Austria | 0–2 | Bundesliga · Austria |
| 2021-07-24 |  Qatarv El SalvadorGold Cup | 3–2 | Gold Cup |
| 2021-07-24 | HJKvHakaVeikkausliiga · Finland | 2–0 | Veikkausliiga · Finland |
| 2021-07-24 | DresdenvIngolstadt2. Bundesliga · Germany | 3–0 | 2. Bundesliga · Germany |
| 2021-07-24 | PalmeirasvFluminenseSerie A · Brazil | 1–0 | Serie A · Brazil |
| 2021-07-24 | Gamba OsakavKashima AntlersJ1 League · Japan | 0–1 | J1 League · Japan |
| 2021-07-24 | JuarezvTolucaLiga MX · Mexico | 1–3 | Liga MX · Mexico |
| 2021-07-24 | LuzernvYoung BoysSuper League · Switzerland | 3–4 | Super League · Switzerland |
| 2021-07-24 | Pau FCvNancyLigue 2 · France | 2–1 | Ligue 2 · France |
| 2021-07-24 | KortrijkvSeraingPro League · Belgium | 2–0 | Pro League · Belgium |
| 2021-07-24 | AmiensvAuxerreLigue 2 · France | 1–2 | Ligue 2 · France |
| 2021-07-24 | TirolvAdmiraBundesliga · Austria | 1–1 | Bundesliga · Austria |
| 2021-07-24 | GremiovAmerica MGSerie A · Brazil | 1–1 | Serie A · Brazil |
| 2021-07-24 | Lokomotiv MoscowvArsenal TulaPremier League · Russia | 3–1 | Premier League · Russia |
| 2021-07-24 | GrenoblevParis FCLigue 2 · France | 0–4 | Ligue 2 · France |
| 2021-07-24 | OostendevCharleroiPro League · Belgium | 0–3 | Pro League · Belgium |
| 2021-07-24 | DunkerquevQuevilly RouenLigue 2 · France | 1–1 | Ligue 2 · France |
| 2021-07-24 | LausannevSt. GallenSuper League · Switzerland | 1–2 | Super League · Switzerland |
| 2021-07-24 | San LorenzovCentral CordobaLiga Profesional · Argentina | 1–0 | Liga Profesional · Argentina |
| 2021-07-24 | Shandong TaishanvChongqing Liangjiang AthleticSuper League · China | 3–1 | Super League · China |
| 2021-07-24 | Academica ClincenivCFR ClujSuperliga · Romania | 1–2 | Superliga · Romania |
| 2021-07-24 | NecaxavSantos LagunaLiga MX · Mexico | 0–3 | Liga MX · Mexico |
| 2021-07-24 | AalborgvMidtjyllandSuperliga · Denmark | 0–1 | Superliga · Denmark |
| 2021-07-24 | Colon Santa FEvLanusLiga Profesional · Argentina | 1–4 | Liga Profesional · Argentina |
| 2021-07-24 | HeidenheimvPaderborn2. Bundesliga · Germany | 0–0 | 2. Bundesliga · Germany |
| 2021-07-24 | FC VoluntarivFC BotosaniSuperliga · Romania | 0–1 | Superliga · Romania |
| 2021-07-24 | ShenzhenvHenan Songshan LongmenSuper League · China | 0–0 | Super League · China |
| 2021-07-24 | Le HavrevGuingampLigue 2 · France | 0–0 | Ligue 2 · France |
| 2021-07-24 | Rubin KazanvSpartak MoscowPremier League · Russia | 1–0 | Premier League · Russia |
| 2021-07-24 | ToulousevAjaccioLigue 2 · France | 2–2 | Ligue 2 · France |
| 2021-07-24 | AltachvLASKBundesliga · Austria | 0–1 | Bundesliga · Austria |
| 2021-07-24 | LegiavWisla PlockEkstraklasa · Poland | 1–0 | Ekstraklasa · Poland |
| 2021-07-24 | Guangzhou CityvGuangzhou FCSuper League · China | 3–3 | Super League · China |
| 2021-07-24 | KhimkivZenitPremier League · Russia | 1–3 | Premier League · Russia |
| 2021-07-24 | Sagan TosuvCerezo OsakaJ1 League · Japan | 3–3 | J1 League · Japan |
| 2021-07-24 | Atlanta UtdvColumbus CrewMLS · United States | 0–1 | MLS · United States |
| 2021-07-24 | Werder BremenvHannover2. Bundesliga · Germany | 1–1 | 2. Bundesliga · Germany |