| 2010-03-16 | HerefordvMorecambeLeague Two · England | 0–1 | League Two · England |
| 2010-03-16 | ReadingvQPRChampionship · England | 1–0 | Championship · England |
| 2010-03-16 | GatesheadvForest GreenNational League · England | 3–1 | National League · England |
| 2010-03-16 | AccringtonvRotherhamLeague Two · England | 2–1 | League Two · England |
| 2010-03-16 | St JohnstonevAberdeenPremiership · Scotland | 1–0 | Premiership · Scotland |
| 2010-03-15 | LiverpoolvPortsmouthPremier League · England | 4–1 | Premier League · England |
| 2010-03-15 | GrossetovMantovaSerie B · Italy | 1–1 | Serie B · Italy |
| 2010-03-15 | DenizlisporvBesiktasSüper Lig · Turkey | 0–1 | Süper Lig · Turkey |
| 2010-03-15 | Ath MadridvOsasunaLa Liga · Spain | 1–0 | La Liga · Spain |
| 2010-03-15 | AlbinoleffevTriestinaSerie B · Italy | 0–3 | Serie B · Italy |
| 2010-03-15 | Pacos FerreiravMaritimoPrimeira Liga · Portugal | 1–0 | Primeira Liga · Portugal |
| 2010-03-15 | MetzvNantesLigue 2 · France | 0–0 | Ligue 2 · France |
| 2010-03-15 | DuisburgvMunich 18602. Bundesliga · Germany | 0–1 | 2. Bundesliga · Germany |
| 2010-03-15 | Notts CountyvBournemouthLeague Two · England | 2–2 | League Two · England |
| 2010-03-14 | VitessevHeerenveenEredivisie · Netherlands | 0–1 | Eredivisie · Netherlands |
| 2010-03-14 | SalamancavSociedadLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2010-03-14 | BarcelonavValenciaLa Liga · Spain | 3–0 | La Liga · Spain |
| 2010-03-14 | AnderlechtvGenkPro League · Belgium | 2–0 | Pro League · Belgium |
| 2010-03-14 | LevadeiakosvXanthiSuper League · Greece | 2–1 | Super League · Greece |
| 2010-03-14 | St PaulivOberhausen2. Bundesliga · Germany | 5–3 | 2. Bundesliga · Germany |
| 2010-03-14 | GalatasarayvAnkaragucuSüper Lig · Turkey | 3–0 | Süper Lig · Turkey |
| 2010-03-14 | BuyuksehyrvDiyarbakirsporSüper Lig · Turkey | 1–0 | Süper Lig · Turkey |
| 2010-03-14 | SunderlandvMan CityPremier League · England | 1–1 | Premier League · England |
| 2010-03-14 | ValladolidvReal MadridLa Liga · Spain | 1–4 | La Liga · Spain |
| 2010-03-14 | VillarrealvXerezLa Liga · Spain | 2–0 | La Liga · Spain |
| 2010-03-14 | OlhanensevBelenensesPrimeira Liga · Portugal | 1–3 | Primeira Liga · Portugal |
| 2010-03-14 | Club BruggevRoeselarePro League · Belgium | 1–0 | Pro League · Belgium |
| 2010-03-14 | WaregemvStandardPro League · Belgium | 1–1 | Pro League · Belgium |
| 2010-03-14 | SantandervZaragozaLa Liga · Spain | 0–0 | La Liga · Spain |
| 2010-03-14 | AjaxvPSV EindhovenEredivisie · Netherlands | 4–1 | Eredivisie · Netherlands |
| 2010-03-14 | Asteras TripolisvPanathinaikosSuper League · Greece | 0–1 | Super League · Greece |
| 2010-03-14 | Man UnitedvFulhamPremier League · England | 3–0 | Premier League · England |
| 2010-03-14 | Willem IIvSpartaEredivisie · Netherlands | 3–1 | Eredivisie · Netherlands |
| 2010-03-14 | FeyenoordvHeraclesEredivisie · Netherlands | 1–1 | Eredivisie · Netherlands |
| 2010-03-14 | BolognavSampdoriaSerie A · Italy | 1–1 | Serie A · Italy |
| 2010-03-14 | AlmeriavMalagaLa Liga · Spain | 1–0 | La Liga · Spain |
| 2010-03-14 | ValenciennesvRennesLigue 1 · France | 0–2 | Ligue 1 · France |
| 2010-03-14 | AlbacetevCeltaLa Liga 2 · Spain | 0–2 | La Liga 2 · Spain |
| 2010-03-14 | ParmavAtalantaSerie A · Italy | 1–0 | Serie A · Italy |
| 2010-03-14 | KaiserslauternvCottbus2. Bundesliga · Germany | 4–1 | 2. Bundesliga · Germany |
| 2010-03-14 | TenerifevEspanolLa Liga · Spain | 4–1 | La Liga · Spain |
| 2010-03-14 | MilanvChievoSerie A · Italy | 1–0 | Serie A · Italy |
| 2010-03-14 | KayserisporvEskisehirsporSüper Lig · Turkey | 1–2 | Süper Lig · Turkey |
| 2010-03-14 | UdinesevPalermoSerie A · Italy | 3–2 | Serie A · Italy |
| 2010-03-14 | HerculesvLas PalmasLa Liga 2 · Spain | 0–1 | La Liga 2 · Spain |
| 2010-03-14 | LarisavErgotelisSuper League · Greece | 1–0 | Super League · Greece |
| 2010-03-14 | PaderbornvHansa Rostock2. Bundesliga · Germany | 2–2 | 2. Bundesliga · Germany |
| 2010-03-14 | Sp LisbonvGuimaraesPrimeira Liga · Portugal | 3–1 | Primeira Liga · Portugal |
| 2010-03-14 | LillevGrenobleLigue 1 · France | 1–0 | Ligue 1 · France |
| 2010-03-14 | PanthrakikosvPanioniosSuper League · Greece | 0–1 | Super League · Greece |