| 2021-08-21 | StokevNott'm ForestChampionship · England | 1–0 | Championship · England |
| 2021-08-21 | QPRvBarnsleyChampionship · England | 2–2 | Championship · England |
| 2021-08-21 | St EtiennevLilleLigue 1 · France | 1–1 | Ligue 1 · France |
| 2021-08-21 | CSKA MoscowvAkhmat GroznyPremier League · Russia | 2–0 | Premier League · Russia |
| 2021-08-21 | DoncastervPortsmouthLeague One · England | 0–0 | League One · England |
| 2021-08-21 | AlavesvMallorcaLa Liga · Spain | 0–1 | La Liga · Spain |
| 2021-08-21 | CracoviavJagielloniaEkstraklasa · Poland | 2–1 | Ekstraklasa · Poland |
| 2021-08-21 | DumbartonvCove RangersLeague One · Scotland | 1–3 | League One · Scotland |
| 2021-08-21 | KasimpasavGiresunsporSüper Lig · Turkey | 2–0 | Süper Lig · Turkey |
| 2021-08-21 | OldhamvColchesterLeague Two · England | 1–2 | League Two · England |
| 2021-08-21 | Vissel KobevKashima AntlersJ1 League · Japan | 1–0 | J1 League · Japan |
| 2021-08-21 | StenhousemuirvCowdenbeathLeague Two · Scotland | 1–1 | League Two · Scotland |
| 2021-08-21 | Minnesota UnitedvSporting Kansas CityMLS · United States | 0–0 | MLS · United States |
| 2021-08-21 | BoltonvOxfordLeague One · England | 2–1 | League One · England |
| 2021-08-21 | FreiburgvDortmundBundesliga · Germany | 2–1 | Bundesliga · Germany |
| 2021-08-21 | GroningenvUtrechtEredivisie · Netherlands | 0–0 | Eredivisie · Netherlands |
| 2021-08-21 | Aston VillavNewcastlePremier League · England | 2–0 | Premier League · England |
| 2021-08-21 | Sligo RoversvDerry CityPremier Division · Ireland | 1–2 | Premier Division · Ireland |
| 2021-08-21 | Sp LisbonvBelenensesPrimeira Liga · Portugal | 2–0 | Primeira Liga · Portugal |
| 2021-08-21 | Sparta RotterdamvHeraclesEredivisie · Netherlands | 1–1 | Eredivisie · Netherlands |
| 2021-08-21 | LeedsvEvertonPremier League · England | 2–2 | Premier League · England |
| 2021-08-21 | CelticvSt MirrenPremiership · Scotland | 6–0 | Premiership · Scotland |
| 2021-08-21 | LutonvBirminghamChampionship · England | 0–5 | Championship · England |
| 2021-08-21 | Sheffield UnitedvHuddersfieldChampionship · England | 1–2 | Championship · England |
| 2021-08-21 | AmiensvSochauxLigue 2 · France | 0–0 | Ligue 2 · France |
| 2021-08-21 | MortonvQueen of SthChampionship · Scotland | 2–3 | Championship · Scotland |
| 2021-08-21 | DerbyvMiddlesbroughChampionship · England | 0–0 | Championship · England |
| 2021-08-21 | DijonvToulouseLigue 2 · France | 2–4 | Ligue 2 · France |
| 2021-08-21 |  El Salvadorv Costa RicaFriendly | 0–0 | Friendly |
| 2021-08-21 | Inter TurkuvIlvesVeikkausliiga · Finland | 2–0 | Veikkausliiga · Finland |
| 2021-08-21 | ValenciennesvRodezLigue 2 · France | 1–4 | Ligue 2 · France |
| 2021-08-21 | IndependientevDefensa y JusticiaLiga Profesional · Argentina | 0–0 | Liga Profesional · Argentina |
| 2021-08-21 | BournemouthvBlackpoolChampionship · England | 2–2 | Championship · England |
| 2021-08-21 | Malmo FFvDegerforsAllsvenskan · Sweden | 3–0 | Allsvenskan · Sweden |
| 2021-08-21 | UralvDynamo MoscowPremier League · Russia | 0–1 | Premier League · Russia |
| 2021-08-21 | CoventryvReadingChampionship · England | 2–1 | Championship · England |
| 2021-08-21 | Man CityvNorwichPremier League · England | 5–0 | Premier League · England |
| 2021-08-21 | TenerifevSp GijonLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2021-08-21 | Krylya SovetovvSochiPremier League · Russia | 1–0 | Premier League · Russia |
| 2021-08-21 | Shonan BellmarevShimizu S-PulseJ1 League · Japan | 1–1 | J1 League · Japan |
| 2021-08-21 | FulhamvHullChampionship · England | 2–0 | Championship · England |
| 2021-08-21 | ZurichvGrasshoppersSuper League · Switzerland | 2–1 | Super League · Switzerland |
| 2021-08-21 | TokushimavUrawa RedsJ1 League · Japan | 0–1 | J1 League · Japan |
| 2021-08-21 | Wolfsberger ACvAdmiraBundesliga · Austria | 3–0 | Bundesliga · Austria |
| 2021-08-21 | StromsgodsetvBrannEliteserien · Norway | 3–1 | Eliteserien · Norway |
| 2021-08-21 | PeterheadvAirdrie UtdLeague One · Scotland | 2–3 | League One · Scotland |
| 2021-08-21 | Kings LynnvSouthendNational League · England | 0–1 | National League · England |
| 2021-08-21 | AtlasvTolucaLiga MX · Mexico | 0–0 | Liga MX · Mexico |
| 2021-08-21 | AlloavQueens ParkLeague One · Scotland | 1–1 | League One · Scotland |
| 2021-08-21 | Pogon SzczecinvStal MielecEkstraklasa · Poland | 4–1 | Ekstraklasa · Poland |