| 2010-04-05 | WrexhamvGatesheadNational League · England | 0–0 | National League · England |
| 2010-04-05 | NorthamptonvTorquayLeague Two · England | 0–0 | League Two · England |
| 2010-04-05 | Sheffield WedsvBristol CityChampionship · England | 0–1 | Championship · England |
| 2010-04-05 | NewcastlevSheffield UnitedChampionship · England | 2–1 | Championship · England |
| 2010-04-04 | GironavSalamancaLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2010-04-04 | AlmeriavMallorcaLa Liga · Spain | 1–1 | La Liga · Spain |
| 2010-04-04 | BirminghamvLiverpoolPremier League · England | 1–1 | Premier League · England |
| 2010-04-04 | FenerbahcevKayserisporSüper Lig · Turkey | 2–0 | Süper Lig · Turkey |
| 2010-04-04 | KoblenzvPaderborn2. Bundesliga · Germany | 2–1 | 2. Bundesliga · Germany |
| 2010-04-04 | FeyenoordvNAC BredaEredivisie · Netherlands | 0–0 | Eredivisie · Netherlands |
| 2010-04-04 | WolfsburgvHoffenheimBundesliga · Germany | 4–0 | Bundesliga · Germany |
| 2010-04-04 | Hansa RostockvAachen2. Bundesliga · Germany | 2–0 | 2. Bundesliga · Germany |
| 2010-04-04 | ValenciavOsasunaLa Liga · Spain | 3–0 | La Liga · Spain |
| 2010-04-04 | OberhausenvKaiserslautern2. Bundesliga · Germany | 2–1 | 2. Bundesliga · Germany |
| 2010-04-04 | AugsburgvGreuther Furth2. Bundesliga · Germany | 1–1 | 2. Bundesliga · Germany |
| 2010-04-04 | HibernianvCelticPremiership · Scotland | 0–1 | Premiership · Scotland |
| 2010-04-04 | Munich 1860vCottbus2. Bundesliga · Germany | 1–2 | 2. Bundesliga · Germany |
| 2010-04-04 | BielefeldvFrankfurt FSV2. Bundesliga · Germany | 2–1 | 2. Bundesliga · Germany |
| 2010-04-04 | SociedadvHerculesLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2010-04-04 | CadizvCastellonLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2010-04-04 | MarseillevLensLigue 1 · France | 1–0 | Ligue 1 · France |
| 2010-04-04 | AuxerrevParis SGLigue 1 · France | 1–1 | Ligue 1 · France |
| 2010-04-04 | SantandervReal MadridLa Liga · Spain | 0–2 | La Liga · Spain |
| 2010-04-04 | HeraclesvNijmegenEredivisie · Netherlands | 2–0 | Eredivisie · Netherlands |
| 2010-04-04 | DiyarbakirsporvGaziantepsporSüper Lig · Turkey | 1–3 | Süper Lig · Turkey |
| 2010-04-04 | Den HaagvAjaxEredivisie · Netherlands | 0–1 | Eredivisie · Netherlands |
| 2010-04-04 | EvertonvWest HamPremier League · England | 2–2 | Premier League · England |
| 2010-04-04 | ValladolidvVillarrealLa Liga · Spain | 0–2 | La Liga · Spain |
| 2010-04-04 | KilmarnockvAberdeenPremiership · Scotland | 2–0 | Premiership · Scotland |
| 2010-04-04 | FulhamvWiganPremier League · England | 2–1 | Premier League · England |
| 2010-04-04 | EskisehirsporvKasimpasaSüper Lig · Turkey | 2–0 | Süper Lig · Turkey |
| 2010-04-04 | BoulognevToulouseLigue 1 · France | 1–1 | Ligue 1 · France |
| 2010-04-04 | Willem IIvPSV EindhovenEredivisie · Netherlands | 0–1 | Eredivisie · Netherlands |
| 2010-04-04 | GetafevEspanolLa Liga · Spain | 1–1 | La Liga · Spain |
| 2010-04-04 | Ath MadridvLa CorunaLa Liga · Spain | 3–0 | La Liga · Spain |
| 2010-04-04 | ManisasporvGenclerbirligiSüper Lig · Turkey | 0–0 | Süper Lig · Turkey |
| 2010-04-04 | HamburgvHannoverBundesliga · Germany | 0–0 | Bundesliga · Germany |
| 2010-04-04 | Sp GijonvXerezLa Liga · Spain | 2–2 | La Liga · Spain |
| 2010-04-03 | BarivRomaSerie A · Italy | 0–1 | Serie A · Italy |
| 2010-04-03 | Las PalmasvCartagenaLa Liga 2 · Spain | 0–1 | La Liga 2 · Spain |
| 2010-04-03 | PrestonvWatfordChampionship · England | 1–1 | Championship · England |
| 2010-04-03 | IntervBolognaSerie A · Italy | 3–0 | Serie A · Italy |
| 2010-04-03 | Queens ParkvMontroseLeague Two · Scotland | 3–0 | League Two · Scotland |
| 2010-04-03 | NicevSochauxLigue 1 · France | 0–0 | Ligue 1 · France |
| 2010-04-03 | DoncastervPlymouthChampionship · England | 1–2 | Championship · England |
| 2010-04-03 | Sheffield UnitedvBarnsleyChampionship · England | 0–0 | Championship · England |
| 2010-04-03 | Leyton OrientvHartlepoolLeague One · England | 1–3 | League One · England |
| 2010-04-03 | MortonvQueen of SthChampionship · Scotland | 3–3 | Championship · Scotland |
| 2010-04-03 | AtalantavSienaSerie A · Italy | 2–0 | Serie A · Italy |
| 2010-04-03 | StevenagevLutonNational League · England | 0–1 | National League · England |