| 2010-04-13 | BenficavSp LisbonPrimeira Liga · Portugal | 2–0 | Primeira Liga · Portugal |
| 2010-04-12 | RecreativovSociedadLa Liga 2 · Spain | 2–0 | La Liga 2 · Spain |
| 2010-04-12 | SwindonvExeterLeague One · England | 1–1 | League One · England |
| 2010-04-12 | StirlingvArbroathLeague One · Scotland | 2–2 | League One · Scotland |
| 2010-04-12 | St PaulivAugsburg2. Bundesliga · Germany | 3–0 | 2. Bundesliga · Germany |
| 2010-04-12 | KayserisporvSivassporSüper Lig · Turkey | 2–2 | Süper Lig · Turkey |
| 2010-04-12 | Airdrie UtdvQueen of SthChampionship · Scotland | 0–1 | Championship · Scotland |
| 2010-04-12 | Albion RvsvStranraerLeague Two · Scotland | 3–1 | League Two · Scotland |
| 2010-04-12 | SetubalvAcademicaPrimeira Liga · Portugal | 1–1 | Primeira Liga · Portugal |
| 2010-04-12 | GuingampvNantesLigue 2 · France | 2–0 | Ligue 2 · France |
| 2010-04-11 | NancyvAuxerreLigue 1 · France | 0–1 | Ligue 1 · France |
| 2010-04-11 | LeixoesvPacos FerreiraPrimeira Liga · Portugal | 2–0 | Primeira Liga · Portugal |
| 2010-04-11 | CartagenavMurciaLa Liga 2 · Spain | 3–2 | La Liga 2 · Spain |
| 2010-04-11 | BolognavLazioSerie A · Italy | 2–3 | Serie A · Italy |
| 2010-04-11 | PanathinaikosvIraklisSuper League · Greece | 2–0 | Super League · Greece |
| 2010-04-11 | PanioniosvLarisaSuper League · Greece | 0–3 | Super League · Greece |
| 2010-04-11 | KasimpasavAnkaragucuSüper Lig · Turkey | 2–0 | Süper Lig · Turkey |
| 2010-04-11 | DenizlisporvEskisehirsporSüper Lig · Turkey | 1–0 | Süper Lig · Turkey |
| 2010-04-11 | MilanvCataniaSerie A · Italy | 2–2 | Serie A · Italy |
| 2010-04-11 | CastellonvCeltaLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2010-04-11 | OsasunavZaragozaLa Liga · Spain | 2–0 | La Liga · Spain |
| 2010-04-11 | PanthrakikosvOlympiakosSuper League · Greece | 0–2 | Super League · Greece |
| 2010-04-11 | UtrechtvDen HaagEredivisie · Netherlands | 0–2 | Eredivisie · Netherlands |
| 2010-04-11 | MallorcavValenciaLa Liga · Spain | 3–2 | La Liga · Spain |
| 2010-04-11 | AjaxvVVV VenloEredivisie · Netherlands | 7–0 | Eredivisie · Netherlands |
| 2010-04-11 | LyonvLilleLigue 1 · France | 1–1 | Ligue 1 · France |
| 2010-04-11 | BlackburnvMan UnitedPremier League · England | 0–0 | Premier League · England |
| 2010-04-11 | La CorunavSantanderLa Liga · Spain | 1–1 | La Liga · Spain |
| 2010-04-11 | WolvesvStokePremier League · England | 0–0 | Premier League · England |
| 2010-04-11 | MaritimovBelenensesPrimeira Liga · Portugal | 3–3 | Primeira Liga · Portugal |
| 2010-04-11 | GroningenvWillem IIEredivisie · Netherlands | 4–0 | Eredivisie · Netherlands |
| 2010-04-11 | EspanolvAth MadridLa Liga · Spain | 3–0 | La Liga · Spain |
| 2010-04-11 | DuisburgvGreuther Furth2. Bundesliga · Germany | 1–1 | 2. Bundesliga · Germany |
| 2010-04-11 | Man CityvBirminghamPremier League · England | 5–1 | Premier League · England |
| 2010-04-11 | NurnbergvWolfsburgBundesliga · Germany | 0–2 | Bundesliga · Germany |
| 2010-04-11 | PSV EindhovenvFeyenoordEredivisie · Netherlands | 0–0 | Eredivisie · Netherlands |
| 2010-04-11 | GenclerbirligivBursasporSüper Lig · Turkey | 0–0 | Süper Lig · Turkey |
| 2010-04-11 | SampdoriavGenoaSerie A · Italy | 1–0 | Serie A · Italy |
| 2010-04-11 | MarseillevNiceLigue 1 · France | 4–1 | Ligue 1 · France |
| 2010-04-11 | LevantevSalamancaLa Liga 2 · Spain | 2–0 | La Liga 2 · Spain |
| 2010-04-11 | CordobavNumanciaLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2010-04-11 | Ath BilbaovAlmeriaLa Liga · Spain | 4–1 | La Liga · Spain |
| 2010-04-11 | XanthivAtromitosSuper League · Greece | 2–1 | Super League · Greece |
| 2010-04-11 | SienavBariSerie A · Italy | 3–2 | Serie A · Italy |
| 2010-04-11 | AberdeenvSt JohnstonePremiership · Scotland | 1–3 | Premiership · Scotland |
| 2010-04-11 | PalermovChievoSerie A · Italy | 3–1 | Serie A · Italy |
| 2010-04-11 | Frankfurt FSVvOberhausen2. Bundesliga · Germany | 1–0 | 2. Bundesliga · Germany |
| 2010-04-11 | LevadeiakosvAEKSuper League · Greece | 0–0 | Super League · Greece |
| 2010-04-11 | PAOKvKavalaSuper League · Greece | 1–0 | Super League · Greece |
| 2010-04-11 | BochumvHamburgBundesliga · Germany | 1–2 | Bundesliga · Germany |