| 2001-04-21 | MansfieldvLeyton OrientLeague Two · England | 2–0 | League Two · England |
| 2001-04-21 | LeganesvJaenLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2001-04-21 | WiganvRotherhamLeague One · England | 0–2 | League One · England |
| 2001-04-21 | Ein FrankfurtvBayern MunichBundesliga · Germany | 0–2 | Bundesliga · Germany |
| 2001-04-21 | LutonvBuryLeague One · England | 1–2 | League One · England |
| 2001-04-21 | MotherwellvSt JohnstonePremiership · Scotland | 0–1 | Premiership · Scotland |
| 2001-04-21 | PlymouthvTorquayLeague Two · England | 3–1 | League Two · England |
| 2001-04-21 |  Moroccov NamibiaFIFA World Cup qualification | 3–0 | FIFA World Cup qualification |
| 2001-04-21 | FenerbahcevGaziantepsporSüper Lig · Turkey | 4–3 | Süper Lig · Turkey |
| 2001-04-21 | MacclesfieldvSouthendLeague Two · England | 1–0 | League Two · England |
| 2001-04-21 | ExetervHalifaxLeague Two · England | 0–0 | League Two · England |
| 2001-04-21 | CottbusvUnterhachingBundesliga · Germany | 1–0 | Bundesliga · Germany |
| 2001-04-21 | FeyenoordvNijmegenEredivisie · Netherlands | 3–0 | Eredivisie · Netherlands |
| 2001-04-21 | East FifevAlbion RvsLeague Two · Scotland | 2–1 | League Two · Scotland |
| 2001-04-21 | CowdenbeathvEast StirlingLeague Two · Scotland | 1–3 | League Two · Scotland |
| 2001-04-21 | MechelenvBeverenPro League · Belgium | 2–2 | Pro League · Belgium |
| 2001-04-21 | PartickvArbroathLeague One · Scotland | 0–1 | League One · Scotland |
| 2001-04-21 | ArsenalvEvertonPremier League · England | 4–1 | Premier League · England |
| 2001-04-21 | FalkirkvClydeChampionship · Scotland | 1–1 | Championship · Scotland |
| 2001-04-21 | YorkvCardiffLeague Two · England | 3–3 | League Two · England |
| 2001-04-21 | SunderlandvNewcastlePremier League · England | 1–1 | Premier League · England |
| 2001-04-21 | WimbledonvNott'm ForestChampionship · England | 2–1 | Championship · England |
| 2001-04-21 | St TruidenvHarelbekePro League · Belgium | 1–1 | Pro League · Belgium |
| 2001-04-21 | BarnetvRochdaleLeague Two · England | 3–0 | League Two · England |
| 2001-04-21 |  Kazakhstanv NepalFIFA World Cup qualification | 4–0 | FIFA World Cup qualification |
| 2001-04-21 | SwanseavOldhamLeague One · England | 1–2 | League One · England |
| 2001-04-21 |  Burkina Fasov MalawiFIFA World Cup qualification | 4–2 | FIFA World Cup qualification |
| 2001-04-21 | AlloavRaith RvsChampionship · Scotland | 1–2 | Championship · Scotland |
| 2001-04-21 | Notts CountyvBristol CityLeague One · England | 2–1 | League One · England |
| 2001-04-21 |  Senegalv AlgeriaFIFA World Cup qualification | 3–0 | FIFA World Cup qualification |
| 2001-04-21 | Roda JCvSpartaEredivisie · Netherlands | 1–0 | Eredivisie · Netherlands |
| 2001-04-21 | IntervFiorentinaSerie A · Italy | 4–2 | Serie A · Italy |
| 2001-04-21 | Schalke 04vHerthaBundesliga · Germany | 3–1 | Bundesliga · Germany |
| 2001-04-21 | Ross CountyvAyrChampionship · Scotland | 0–1 | Championship · Scotland |
| 2001-04-21 | GroningenvRoosendaalEredivisie · Netherlands | 2–0 | Eredivisie · Netherlands |
| 2001-04-21 | BradfordvDerbyPremier League · England | 2–0 | Premier League · England |
| 2001-04-21 | ElginvBrechinLeague Two · Scotland | 0–3 | League Two · Scotland |
| 2001-04-21 | WolvesvBlackburnChampionship · England | 0–0 | Championship · England |
| 2001-04-21 | IpswichvCoventryPremier League · England | 2–0 | Premier League · England |
| 2001-04-21 | WycombevSwindonLeague One · England | 0–0 | League One · England |
| 2001-04-21 | DundeevRangersPremiership · Scotland | 0–3 | Premiership · Scotland |
| 2001-04-21 | NAC BredavAZ AlkmaarEredivisie · Netherlands | 0–0 | Eredivisie · Netherlands |
| 2001-04-21 | Werder BremenvWolfsburgBundesliga · Germany | 2–3 | Bundesliga · Germany |
| 2001-04-21 | Queen of SthvStenhousemuirLeague One · Scotland | 1–3 | League One · Scotland |
| 2001-04-21 | AirdrievInverness CChampionship · Scotland | 1–1 | Championship · Scotland |
| 2001-04-21 | BerwickvQueens ParkLeague One · Scotland | 1–0 | League One · Scotland |
| 2001-04-21 | GraafschapvTwenteEredivisie · Netherlands | 4–0 | Eredivisie · Netherlands |
| 2001-04-21 | CarlislevBrightonLeague Two · England | 0–0 | League Two · England |
| 2001-04-21 | HartlepoolvScunthorpeLeague Two · England | 1–0 | League Two · England |
| 2001-04-21 | GillinghamvWest BromChampionship · England | 1–2 | Championship · England |