| 2000-04-18 | TranmerevPort ValeChampionship · England | 2–1 | Championship · England |
| 2000-04-18 | StenhousemuirvHamiltonLeague One · Scotland | 0–1 | League One · Scotland |
| 2000-04-18 | RochdalevPeterboroLeague Two · England | 1–2 | League Two · England |
| 2000-04-18 | OldhamvChesterfieldLeague One · England | 1–2 | League One · England |
| 2000-04-18 | AberdeenvDundeePremiership · Scotland | 0–1 | Premiership · Scotland |
| 2000-04-18 | LutonvBristol CityLeague One · England | 1–2 | League One · England |
| 2000-04-18 | BurnleyvGillinghamLeague One · England | 0–3 | League One · England |
| 2000-04-17 | BochumvM'gladbach2. Bundesliga · Germany | 2–2 | 2. Bundesliga · Germany |
| 2000-04-17 | PanathinaikosvOFISuper League · Greece | 3–2 | Super League · Greece |
| 2000-04-17 | ChemnitzvNurnberg2. Bundesliga · Germany | 1–1 | 2. Bundesliga · Germany |
| 2000-04-17 | XanthivPAOKSuper League · Greece | 1–2 | Super League · Greece |
| 2000-04-17 | Est AmadoravBoavistaPrimeira Liga · Portugal | 1–2 | Primeira Liga · Portugal |
| 2000-04-16 | Den BoschvNijmegenEredivisie · Netherlands | 1–1 | Eredivisie · Netherlands |
| 2000-04-16 | CeltavNumanciaLa Liga · Spain | 0–0 | La Liga · Spain |
| 2000-04-16 | SetubalvSp BragaPrimeira Liga · Portugal | 0–2 | Primeira Liga · Portugal |
| 2000-04-16 | MotherwellvKilmarnockPremiership · Scotland | 2–0 | Premiership · Scotland |
| 2000-04-16 | SamsunsporvIstanbulsporSüper Lig · Turkey | 1–0 | Süper Lig · Turkey |
| 2000-04-16 | PanahaikivAEKSuper League · Greece | 1–1 | Super League · Greece |
| 2000-04-16 | ProodeytikivTrikalaSuper League · Greece | 1–0 | Super League · Greece |
| 2000-04-16 | GraafschapvFeyenoordEredivisie · Netherlands | 0–1 | Eredivisie · Netherlands |
| 2000-04-16 | ParmavVeneziaSerie A · Italy | 3–1 | Serie A · Italy |
| 2000-04-16 | SantandervValladolidLa Liga · Spain | 1–1 | La Liga · Spain |
| 2000-04-16 | Greuther FurthvOffenbach2. Bundesliga · Germany | 1–1 | 2. Bundesliga · Germany |
| 2000-04-16 | AjaxvAZ AlkmaarEredivisie · Netherlands | 4–1 | Eredivisie · Netherlands |
| 2000-04-16 | SalamancavLas PalmasLa Liga 2 · Spain | 0–2 | La Liga 2 · Spain |
| 2000-04-16 | TenerifevRecreativoLa Liga 2 · Spain | 1–2 | La Liga 2 · Spain |
| 2000-04-16 | FC KolnvMainz2. Bundesliga · Germany | 1–0 | 2. Bundesliga · Germany |
| 2000-04-16 | AlbacetevCordobaLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2000-04-16 |  Dominican Republicv Trinidad and TobagoFIFA World Cup qualification | 0–1 | FIFA World Cup qualification |
| 2000-04-16 | Gil VicentevRio AvePrimeira Liga · Portugal | 4–0 | Primeira Liga · Portugal |
| 2000-04-16 | GetafevOsasunaLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2000-04-16 | KarlsruhevHannover2. Bundesliga · Germany | 1–3 | 2. Bundesliga · Germany |
| 2000-04-16 | PSV EindhovenvCambuurEredivisie · Netherlands | 1–0 | Eredivisie · Netherlands |
| 2000-04-16 | VillarrealvMeridaLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2000-04-16 | PanioniosvKavalaSuper League · Greece | 1–1 | Super League · Greece |
| 2000-04-16 |  Bahamasv HaitiFIFA World Cup qualification | 0–4 | FIFA World Cup qualification |
| 2000-04-16 |  Belizev El SalvadorFIFA World Cup qualification | 1–3 | FIFA World Cup qualification |
| 2000-04-16 | VansporvAnkaragucuSüper Lig · Turkey | 2–3 | Süper Lig · Turkey |
| 2000-04-16 | BenficavBelenensesPrimeira Liga · Portugal | 2–3 | Primeira Liga · Portugal |
| 2000-04-16 | PerugiavPiacenzaSerie A · Italy | 2–0 | Serie A · Italy |
| 2000-04-16 | CagliarivRegginaSerie A · Italy | 0–1 | Serie A · Italy |
| 2000-04-16 | HarelbekevWesterloPro League · Belgium | 3–1 | Pro League · Belgium |
| 2000-04-16 |  Nicaraguav HondurasFIFA World Cup qualification | 0–1 | FIFA World Cup qualification |
| 2000-04-16 | UnterhachingvHansa RostockBundesliga · Germany | 1–1 | Bundesliga · Germany |
| 2000-04-16 | LevantevToledoLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2000-04-16 |  Surinamev CubaFIFA World Cup qualification | 0–0 | FIFA World Cup qualification |
| 2000-04-16 | Ath MadridvMalagaLa Liga · Spain | 2–2 | La Liga · Spain |
| 2000-04-16 |  Barbadosv ArubaFIFA World Cup qualification | 4–0 | FIFA World Cup qualification |
| 2000-04-16 | MaritimovLeiriaPrimeira Liga · Portugal | 0–0 | Primeira Liga · Portugal |
| 2000-04-16 | ExtremaduravSp GijonLa Liga 2 · Spain | 2–2 | La Liga 2 · Spain |