| 2001-04-28 | Albion RvsvCowdenbeathLeague Two · Scotland | 0–0 | League Two · Scotland |
| 2001-04-28 | LorientvWasquehalLigue 2 · France | 2–0 | Ligue 2 · France |
| 2001-04-28 | BeverenvAalstPro League · Belgium | 1–0 | Pro League · Belgium |
| 2001-04-28 | SochauxvNiceLigue 2 · France | 5–1 | Ligue 2 · France |
| 2001-04-28 | StranraervPartickLeague One · Scotland | 3–4 | League One · Scotland |
| 2001-04-28 | BochumvSchalke 04Bundesliga · Germany | 1–1 | Bundesliga · Germany |
| 2001-04-28 | ErzurumsporvRizesporSüper Lig · Turkey | 0–0 | Süper Lig · Turkey |
| 2001-04-28 | FC KolnvCottbusBundesliga · Germany | 4–0 | Bundesliga · Germany |
| 2001-04-28 | MartiguesvNiortLigue 2 · France | 1–1 | Ligue 2 · France |
| 2001-04-28 | Man CityvWest HamPremier League · England | 1–0 | Premier League · England |
| 2001-04-28 | BournemouthvNorthamptonLeague One · England | 2–0 | League One · England |
| 2001-04-28 | GentvLokerenPro League · Belgium | 3–2 | Pro League · Belgium |
| 2001-04-28 | CoventryvLiverpoolPremier League · England | 0–2 | Premier League · England |
| 2001-04-28 | WesterlovSt TruidenPro League · Belgium | 4–6 | Pro League · Belgium |
| 2001-04-28 | For SittardvGroningenEredivisie · Netherlands | 1–1 | Eredivisie · Netherlands |
| 2001-04-28 | Real MadridvOsasunaLa Liga · Spain | 1–1 | La Liga · Spain |
| 2001-04-28 | MiddlesbroughvMan UnitedPremier League · England | 0–2 | Premier League · England |
| 2001-04-28 | FulhamvWimbledonChampionship · England | 1–1 | Championship · England |
| 2001-04-28 | EvertonvBradfordPremier League · England | 2–1 | Premier League · England |
| 2001-04-28 | Queens ParkvForfarLeague One · Scotland | 0–2 | League One · Scotland |
| 2001-04-28 | OxfordvSwanseaLeague One · England | 3–1 | League One · England |
| 2001-04-28 | RennesvBordeauxLigue 1 · France | 1–2 | Ligue 1 · France |
| 2001-04-28 | SpartavHeerenveenEredivisie · Netherlands | 1–3 | Eredivisie · Netherlands |
| 2001-04-28 | AnderlechtvGerminalPro League · Belgium | 7–0 | Pro League · Belgium |
| 2001-04-28 | VicenzavParmaSerie A · Italy | 0–1 | Serie A · Italy |
| 2001-04-28 | ChateaurouxvAjaccioLigue 2 · France | 2–2 | Ligue 2 · France |
| 2001-04-28 | Ath MadridvMurciaLa Liga 2 · Spain | 0–3 | La Liga 2 · Spain |
| 2001-04-28 | WrexhamvMillwallLeague One · England | 1–1 | League One · England |
| 2001-04-28 | LeedsvChelseaPremier League · England | 2–0 | Premier League · England |
| 2001-04-28 | West BromvHuddersfieldChampionship · England | 1–1 | Championship · England |
| 2001-04-28 | BetisvLleidaLa Liga 2 · Spain | 4–1 | La Liga 2 · Spain |
| 2001-04-28 | StuttgartvWerder BremenBundesliga · Germany | 2–1 | Bundesliga · Germany |
| 2001-04-28 | East StirlingvMontroseLeague Two · Scotland | 0–1 | League Two · Scotland |
| 2001-04-28 | GuimaraesvBelenensesPrimeira Liga · Portugal | 1–1 | Primeira Liga · Portugal |
| 2001-04-28 | HalifaxvDarlingtonLeague Two · England | 1–0 | League Two · England |
| 2001-04-28 | IstanbulsporvSiirt Jet-PASüper Lig · Turkey | 2–1 | Süper Lig · Turkey |
| 2001-04-28 | Willem IIvPSV EindhovenEredivisie · Netherlands | 1–1 | Eredivisie · Netherlands |
| 2001-04-28 | LincolnvPlymouthLeague Two · England | 2–1 | League Two · England |
| 2001-04-28 | PeterheadvEast FifeLeague Two · Scotland | 2–1 | League Two · Scotland |
| 2001-04-28 | HullvChesterfieldLeague Two · England | 3–1 | League Two · England |
| 2001-04-28 | Paris SGv MonacoLigue 1 · France | 1–1 | Ligue 1 · France |
| 2001-04-28 | DerbyvArsenalPremier League · England | 1–2 | Premier League · England |
| 2001-04-28 | Raith RvsvAirdrieChampionship · Scotland | 5–0 | Championship · Scotland |
| 2001-04-28 | CambridgevWiganLeague One · England | 1–2 | League One · England |
| 2001-04-28 | GueugnonvNancyLigue 2 · France | 1–1 | Ligue 2 · France |
| 2001-04-28 | HamiltonvElginLeague Two · Scotland | 3–0 | League Two · Scotland |
| 2001-04-28 | GalatasarayvAdanasporSüper Lig · Turkey | 4–1 | Süper Lig · Turkey |
| 2001-04-28 | CannesvBeauvaisLigue 2 · France | 0–1 | Ligue 2 · France |
| 2001-04-28 | OldhamvStokeLeague One · England | 1–2 | League One · England |
| 2001-04-28 | WalsallvBristol RvsLeague One · England | 2–1 | League One · England |