| 2010-12-05 | Rio AvevBeira MarPrimeira Liga · Portugal | 1–1 | Primeira Liga · Portugal |
| 2010-12-05 | AtromitosvAEKSuper League · Greece | 1–1 | Super League · Greece |
| 2010-12-05 | XanthivOlympiakos VolouSuper League · Greece | 1–0 | Super League · Greece |
| 2010-12-05 | Den HaagvAZ AlkmaarEredivisie · Netherlands | 0–2 | Eredivisie · Netherlands |
| 2010-12-05 | LeccevGenoaSerie A · Italy | 1–3 | Serie A · Italy |
| 2010-12-05 | SampdoriavBariSerie A · Italy | 3–0 | Serie A · Italy |
| 2010-12-05 | TorinovSienaSerie B · Italy | 1–1 | Serie B · Italy |
| 2010-12-05 | ParmavUdineseSerie A · Italy | 2–1 | Serie A · Italy |
| 2010-12-05 | UtrechtvHeerenveenEredivisie · Netherlands | 2–1 | Eredivisie · Netherlands |
| 2010-12-05 | CeltavLas PalmasLa Liga 2 · Spain | 2–0 | La Liga 2 · Spain |
| 2010-12-05 | FenerbahcevKarabuksporSüper Lig · Turkey | 2–1 | Süper Lig · Turkey |
| 2010-12-05 | Erzgebirge AuevIngolstadt2. Bundesliga · Germany | 1–1 | 2. Bundesliga · Germany |
| 2010-12-05 | West BromvNewcastlePremier League · England | 3–1 | Premier League · England |
| 2010-12-05 | AlmeriavZaragozaLa Liga · Spain | 1–1 | La Liga · Spain |
| 2010-12-05 | LarisavPAOKSuper League · Greece | 1–2 | Super League · Greece |
| 2010-12-05 | Paris SGvBrestLigue 1 · France | 3–1 | Ligue 1 · France |
| 2010-12-05 | EspanolvSp GijonLa Liga · Spain | 1–0 | La Liga · Spain |
| 2010-12-05 | NurnbergvDortmundBundesliga · Germany | 0–2 | Bundesliga · Germany |
| 2010-12-05 | ArisvAsteras TripolisSuper League · Greece | 1–0 | Super League · Greece |
| 2010-12-05 | WaregemvAnderlechtPro League · Belgium | 1–2 | Pro League · Belgium |
| 2010-12-05 | CataniavJuventusSerie A · Italy | 1–3 | Serie A · Italy |
| 2010-12-05 | PortimonensevSp LisbonPrimeira Liga · Portugal | 1–3 | Primeira Liga · Portugal |
| 2010-12-05 | KavalavOlympiakosSuper League · Greece | 0–1 | Super League · Greece |
| 2010-12-05 | BesiktasvBursasporSüper Lig · Turkey | 1–0 | Süper Lig · Turkey |
| 2010-12-05 | VicenzavFrosinoneSerie B · Italy | 1–0 | Serie B · Italy |
| 2010-12-05 | KonyasporvGenclerbirligiSüper Lig · Turkey | 2–1 | Süper Lig · Turkey |
| 2010-12-05 | Club BruggevWesterloPro League · Belgium | 4–3 | Pro League · Belgium |
| 2010-12-05 |  Grenadav CubaCFU Caribbean Cup | 0–1 | CFU Caribbean Cup |
| 2010-12-05 | St EtiennevBordeauxLigue 1 · France | 2–2 | Ligue 1 · France |
| 2010-12-05 | ElchevSalamancaLa Liga 2 · Spain | 3–1 | La Liga 2 · Spain |
| 2010-12-05 | LeverkusenvFC KolnBundesliga · Germany | 3–2 | Bundesliga · Germany |
| 2010-12-05 | Willem IIvFeyenoordEredivisie · Netherlands | 1–1 | Eredivisie · Netherlands |
| 2010-12-05 |  Kuwaitv Saudi ArabiaGulf Cup | 1–0 | Gulf Cup |
| 2010-12-05 | NicevMarseilleLigue 1 · France | 1–0 | Ligue 1 · France |
| 2010-12-05 | Munich 1860vHertha2. Bundesliga · Germany | 1–0 | 2. Bundesliga · Germany |
| 2010-12-04 | SochauxvValenciennesLigue 1 · France | 2–1 | Ligue 1 · France |
| 2010-12-04 | Barcelona BvValladolidLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2010-12-04 | FreiburgvHamburgBundesliga · Germany | 1–0 | Bundesliga · Germany |
| 2010-12-04 | AlloavPeterheadLeague One · Scotland | 2–2 | League One · Scotland |
| 2010-12-04 | MillwallvScunthorpeChampionship · England | 3–0 | Championship · England |
| 2010-12-04 | DerbyvNorwichChampionship · England | 1–2 | Championship · England |
| 2010-12-04 | VaresevRegginaSerie B · Italy | 1–0 | Serie B · Italy |
| 2010-12-04 | WolfsburgvWerder BremenBundesliga · Germany | 0–0 | Bundesliga · Germany |
| 2010-12-04 | OsasunavBarcelonaLa Liga · Spain | 0–3 | La Liga · Spain |
| 2010-12-04 | PortogruarovAtalantaSerie B · Italy | 1–2 | Serie B · Italy |
| 2010-12-04 | ChievovRomaSerie A · Italy | 2–2 | Serie A · Italy |
| 2010-12-04 | CartagenavAlbaceteLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2010-12-04 | PSV EindhovenvHeraclesEredivisie · Netherlands | 5–2 | Eredivisie · Netherlands |
| 2010-12-04 | ToulousevCaenLigue 1 · France | 1–0 | Ligue 1 · France |
| 2010-12-04 | BirminghamvTottenhamPremier League · England | 1–1 | Premier League · England |