| 2022-07-24 | Sporting Kansas CityvLos Angeles FCMLS · United States | 0–2 | MLS · United States |
| 2022-07-24 | Vancouver WhitecapsvChicago FireMLS · United States | 1–3 | MLS · United States |
| 2022-07-18 | Real Salt LakevSporting Kansas CityMLS · United States | 3–0 | MLS · United States |
| 2022-07-18 | Portland TimbersvVancouver WhitecapsMLS · United States | 1–1 | MLS · United States |
| 2022-07-18 | Columbus CrewvFC CincinnatiMLS · United States | 2–0 | MLS · United States |
| 2022-07-18 | San Jose EarthquakesvHouston DynamoMLS · United States | 1–2 | MLS · United States |
| 2022-07-18 | Nashville SCvLos Angeles FCMLS · United States | 1–2 | MLS · United States |
| 2022-07-17 | Chicago FirevSeattle SoundersMLS · United States | 1–0 | MLS · United States |
| 2022-07-17 | CF MontrealvToronto FCMLS · United States | 1–0 | MLS · United States |
| 2022-07-17 | Philadelphia UnionvNew England RevolutionMLS · United States | 2–1 | MLS · United States |
| 2022-07-17 | Minnesota UnitedvDC UnitedMLS · United States | 2–0 | MLS · United States |
| 2022-07-17 | New York Red BullsvNew York CityMLS · United States | 0–1 | MLS · United States |
| 2022-07-17 | Colorado RapidsvLos Angeles GalaxyMLS · United States | 2–0 | MLS · United States |
| 2022-07-17 | FC DallasvAustin FCMLS · United States | 1–1 | MLS · United States |
| 2022-07-17 | Atlanta UtdvOrlando CityMLS · United States | 1–1 | MLS · United States |
| 2022-07-17 | Inter MiamivCharlotteMLS · United States | 3–2 | MLS · United States |
| 2022-07-14 | FC DallasvNew York CityMLS · United States | 0–1 | MLS · United States |
| 2022-07-14 | Chicago FirevToronto FCMLS · United States | 2–0 | MLS · United States |
| 2022-07-14 | Nashville SCvSeattle SoundersMLS · United States | 1–0 | MLS · United States |
| 2022-07-14 | Minnesota UnitedvSporting Kansas CityMLS · United States | 1–1 | MLS · United States |
| 2022-07-14 | DC UnitedvColumbus CrewMLS · United States | 2–2 | MLS · United States |
| 2022-07-14 | Colorado RapidsvOrlando CityMLS · United States | 1–1 | MLS · United States |
| 2022-07-14 | Atlanta UtdvReal Salt LakeMLS · United States | 2–1 | MLS · United States |
| 2022-07-14 | Los Angeles GalaxyvSan Jose EarthquakesMLS · United States | 2–3 | MLS · United States |
| 2022-07-14 | FC CincinnativVancouver WhitecapsMLS · United States | 2–2 | MLS · United States |
| 2022-07-14 | Inter MiamivPhiladelphia UnionMLS · United States | 1–2 | MLS · United States |
| 2022-07-13 | Austin FCvHouston DynamoMLS · United States | 3–1 | MLS · United States |
| 2022-07-10 | FC CincinnativNew York Red BullsMLS · United States | 1–1 | MLS · United States |
| 2022-07-10 | CF MontrealvSporting Kansas CityMLS · United States | 1–2 | MLS · United States |
| 2022-07-10 | Orlando CityvInter MiamiMLS · United States | 1–0 | MLS · United States |
| 2022-07-10 | CharlottevNashville SCMLS · United States | 4–1 | MLS · United States |
| 2022-07-10 | Chicago FirevColumbus CrewMLS · United States | 2–3 | MLS · United States |
| 2022-07-10 | Toronto FCvSan Jose EarthquakesMLS · United States | 2–2 | MLS · United States |
| 2022-07-10 | Real Salt LakevColorado RapidsMLS · United States | 2–2 | MLS · United States |
| 2022-07-10 | Atlanta UtdvAustin FCMLS · United States | 0–3 | MLS · United States |
| 2022-07-10 | Houston DynamovFC DallasMLS · United States | 2–2 | MLS · United States |
| 2022-07-09 | Vancouver WhitecapsvMinnesota UnitedMLS · United States | 1–3 | MLS · United States |
| 2022-07-09 | New York CityvNew England RevolutionMLS · United States | 4–2 | MLS · United States |
| 2022-07-09 | Philadelphia UnionvDC UnitedMLS · United States | 7–0 | MLS · United States |
| 2022-07-09 | Los Angeles FCvLos Angeles GalaxyMLS · United States | 3–2 | MLS · United States |
| 2022-07-09 | Seattle SoundersvPortland TimbersMLS · United States | 0–3 | MLS · United States |
| 2022-07-05 | FC DallasvInter MiamiMLS · United States | 1–1 | MLS · United States |
| 2022-07-05 | Orlando CityvDC UnitedMLS · United States | 3–5 | MLS · United States |
| 2022-07-05 | Colorado RapidsvAustin FCMLS · United States | 2–3 | MLS · United States |
| 2022-07-05 | Los Angeles GalaxyvCF MontrealMLS · United States | 4–0 | MLS · United States |
| 2022-07-04 | Sporting Kansas CityvNew York Red BullsMLS · United States | 0–1 | MLS · United States |
| 2022-07-04 | San Jose EarthquakesvChicago FireMLS · United States | 2–1 | MLS · United States |
| 2022-07-04 | New England RevolutionvFC CincinnatiMLS · United States | 2–2 | MLS · United States |
| 2022-07-04 | Houston DynamovCharlotteMLS · United States | 1–2 | MLS · United States |
| 2022-07-04 | Nashville SCvPortland TimbersMLS · United States | 2–2 | MLS · United States |