| 2022-02-13 | EibarvFuenlabradaLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2022-02-13 | OviedovHuescaLa Liga 2 · Spain | 3–3 | La Liga 2 · Spain |
| 2022-02-12 | IbizavCartagenaLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2022-02-12 | MirandesvSp GijonLa Liga 2 · Spain | 0–3 | La Liga 2 · Spain |
| 2022-02-12 | MalagavAlmeriaLa Liga 2 · Spain | 0–1 | La Liga 2 · Spain |
| 2022-02-12 | ValladolidvGironaLa Liga 2 · Spain | 2–2 | La Liga 2 · Spain |
| 2022-02-11 | LeganesvZaragozaLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2022-02-06 | CartagenavLas PalmasLa Liga 2 · Spain | 0–2 | La Liga 2 · Spain |
| 2022-02-06 | TenerifevLeganesLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2022-02-06 | AmorebietavOviedoLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2022-02-06 | FuenlabradavValladolidLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2022-02-06 | HuescavMirandesLa Liga 2 · Spain | 4–0 | La Liga 2 · Spain |
| 2022-02-05 | Sp GijonvEibarLa Liga 2 · Spain | 0–1 | La Liga 2 · Spain |
| 2022-02-05 | GironavPonferradinaLa Liga 2 · Spain | 3–0 | La Liga 2 · Spain |
| 2022-02-05 | ZaragozavMalagaLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2022-02-05 | Sociedad BvLugoLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2022-02-04 | AlmeriavIbizaLa Liga 2 · Spain | 2–0 | La Liga 2 · Spain |
| 2022-02-04 | BurgosvAlcorconLa Liga 2 · Spain | 3–1 | La Liga 2 · Spain |
| 2022-01-31 | IbizavZaragozaLa Liga 2 · Spain | 2–2 | La Liga 2 · Spain |
| 2022-01-30 | LeganesvAlcorconLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2022-01-30 | PonferradinavTenerifeLa Liga 2 · Spain | 1–2 | La Liga 2 · Spain |
| 2022-01-30 | MirandesvMalagaLa Liga 2 · Spain | 3–0 | La Liga 2 · Spain |
| 2022-01-30 | CartagenavFuenlabradaLa Liga 2 · Spain | 3–0 | La Liga 2 · Spain |
| 2022-01-30 | Las PalmasvSociedad BLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2022-01-29 | LugovBurgosLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2022-01-29 | EibarvHuescaLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2022-01-29 | OviedovAlmeriaLa Liga 2 · Spain | 2–0 | La Liga 2 · Spain |
| 2022-01-29 | AmorebietavGironaLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2022-01-28 | ValladolidvSp GijonLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2022-01-24 | Sociedad BvCartagenaLa Liga 2 · Spain | 1–2 | La Liga 2 · Spain |
| 2022-01-24 | AlmeriavEibarLa Liga 2 · Spain | 0–2 | La Liga 2 · Spain |
| 2022-01-23 | AlcorconvMirandesLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2022-01-23 | HuescavPonferradinaLa Liga 2 · Spain | 1–2 | La Liga 2 · Spain |
| 2022-01-23 | BurgosvLeganesLa Liga 2 · Spain | 4–0 | La Liga 2 · Spain |
| 2022-01-23 | Sp GijonvAmorebietaLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2022-01-23 | GironavLugoLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2022-01-22 | MalagavIbizaLa Liga 2 · Spain | 0–5 | La Liga 2 · Spain |
| 2022-01-22 | FuenlabradavLas PalmasLa Liga 2 · Spain | 3–2 | La Liga 2 · Spain |
| 2022-01-22 | ZaragozavValladolidLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2022-01-21 | TenerifevOviedoLa Liga 2 · Spain | 4–0 | La Liga 2 · Spain |
| 2022-01-19 | LugovAlmeriaLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2022-01-10 | OviedovEibarLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2022-01-09 | LugovMirandesLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2022-01-09 | GironavFuenlabradaLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2022-01-09 | Las PalmasvAlmeriaLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2022-01-09 | PonferradinavZaragozaLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2022-01-09 | MalagavSp GijonLa Liga 2 · Spain | 2–2 | La Liga 2 · Spain |
| 2022-01-08 | CartagenavHuescaLa Liga 2 · Spain | 0–3 | La Liga 2 · Spain |
| 2022-01-08 | IbizavAlcorconLa Liga 2 · Spain | 6–2 | La Liga 2 · Spain |
| 2022-01-08 | ValladolidvBurgosLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |